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Minimal relapse risk and early normalization of survival for patients with Burkitt lymphoma treated with intensive immunochemotherapy : an international study of 264 real-world patients

Non-endemic Burkitt lymphoma (BL) is a rare germinal centre B-cell-derived malignancy with the genetic hallmark of MYC gene translocation and with rapid tumour growth as a distinct clinical feature. To investigate treatment outcomes, loss of lifetime and relapse risk in adult BL patients treated with intensive immunochemotherapy, retrospective clinic-based and population-based lymphoma registries

'Famous from all antiquity' : Etna in Classical Myth and Romantic Poetry

In the early eighteenth century, the Sicilian volcano Etna was still primarily familiar to European culture through its many classical associations. This chapter examines the interaction between classical accounts of Etna and other, developing genres of describing and representing that mountain in the writings of some famous eighteenth-century travelers and ‘natural philosophers’. In paving the wa

NTRK fusions in osteosarcoma are rare and non-functional events

Neurotrophic tyrosine receptor kinase (NTRK) fusions are promising molecular targets that have been described in a broad range of malignant tumours. Fusions commonly lead to the expression of chimeric proteins with constitutive tyrosine kinase activation that drives tumorigenesis. Despite a low prevalence among most solid tumours (

Potential Risk Factors and Prevalence of Voice Symptoms in Students Starting Their Teacher Education

The aim of the present study was to determine prevalence of voice problems and potential risk factors in teacher students at the start of their education. A total of 1494 students from seven teacher education schools participated in the study. The students answered a questionnaire about 11 risk factors, and one with six questions about voice symptoms, Screen6, and 30 statements in the Voice Handic

Measurement of jet-substructure observables in top quark, W boson and light jet production in proton-proton collisions at √s = 13 TeV with the ATLAS detector

A measurement of jet substructure observables is presented using data collected in 2016 by the ATLAS experiment at the LHC with proton-proton collisions at s = 13 TeV. Large-radius jets groomed with the trimming and soft-drop algorithms are studied. Dedicated event selections are used to study jets produced by light quarks or gluons, and hadronically decaying top quarks and W bosons. The observabl

Flux identification methods of sedimentation

Any reasonable model of sedimentation contains the nonlinear hindered-settling flux function. If one assumes ideal conditions and no compression, then there exist several theoretically possible ways of identifying a large part of the flux function from only one experiment by means of formulas derived from the theory of partial differential equations. Such identification methods, including new resu

Waveform Iteration with asynchronous communication

Consider the coupling of two multi-physics systems of time-dependent ODEs. We propose a new Waveform iteration type method for coupling which uses asynchronous communication to be both parallel in time and fast in convergence. Analytical results show convergence in the continuous setting and numerical results for two coupled head equations show good performance of this method, which is both parall

Comparison of Fragmentation Functions for Jets Dominated by Light Quarks and Gluons from pp and Pb+Pb Collisions in ATLAS

Charged-particle fragmentation functions for jets azimuthally balanced by a high-transverse-momentum, prompt, isolated photon are measured in 25 pb-1 of pp and 0.49 nb-1 of Pb+Pb collision data at 5.02 TeV per nucleon pair recorded with the ATLAS detector at the Large Hadron Collider. The measurements are compared to predictions of Monte Carlo generators and to measurements of inclusively selected