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Protracted oxygenation across the Cambrian–Ordovician transition : A key initiator of the Great Ordovician Biodiversification Event?

Fluctuations in marine oxygen concentrations have been invoked as a primary driver for changes in biodiversity throughout Earth history. Expansions in reducing marine conditions are commonly invoked as key causal mechanisms for mass extinctions, while increases in marine oxygenation are becoming an increasingly common causal mechanism invoked for biodiversification events. Here we utilize a multip

The Role of Cow’s Milk Consumption in Breast Cancer Initiation and Progression

Purpose of Review: This review evaluates cow milk’s impact on breast carcinogenesis by linking recent epidemiological evidence and new insights into the molecular signaling of milk and its constituents in breast cancer (BCa) pathogenesis. Recent Findings: Recent prospective cohort studies support the association between cow’s milk consumption and the risk of estrogen receptor-α-positive (ER+) BCa.

Assessing the importance of predictors of adherence to a digital self‑management intervention for osteoarthritis

OBJECTIVE: Treatment adherence is suggested to be associated with greater improvement in patient outcomes. Despite the growing use of digital therapeutics in osteoarthritis management, there is limited evidence of person-level factors influencing adherence to these interventions in real-world settings. We aimed to determine the relative importance of factors influencing adherence to a digital self

Incipient dementia and avoidable hospital admission in persons with osteoarthritis

OBJECTIVE: To investigate the associations between incipient dementia (ID) and hospitalization for ambulatory care sensitive conditions (ACSCs) among people with osteoarthritis (OA) of the peripheral joints.METHODS: Among individuals aged 51-99 years residing in Skåne, Sweden, in 2009, we identified those with a doctor-diagnosed OA and no dementia during 1998-2009 (n ​= ​57,733). Treating ID as a

The data treadmill : water governance and the politics of pollution in rural Ireland

This paper draws on fieldwork in rural Ireland to argue that environmental data can reinforce knowledge systems that shield structural problems and blunt efforts to rethink the role of community engagement in environmental governance. It offers a cautionary reading of how data has been instrumentalised by the EU and Irish State by showing how data diffuses responsibility and depoliticises environm

Covid-19 : crisis, emotional governance and populist fantasy narratives

This short article discusses how different fantasy narratives have come together during the Covid-19 crisis in various far-right movements, parties and audiences across the world and how much of these fantasies rely on racialised and gendered notions of a fantastical world-order in which particular forms of emotional governance provide a relief and sense of security to certain societal groups. Thi

Malmö Breast ImaginG database: objectives and development

PurposeWe describe the design and implementation of the Malmö Breast ImaginG (M-BIG) database, which will support research projects investigating various aspects of current and future breast cancer screening programs. Specifically, M-BIG will provide clinical data to: 1. investigate the effect of breast cancer screening on breast cancer prognosis and mortality; 2. develop and validate the use of a

Lived experiences of physical therapists treating traumatic knee injury using integrated psychological training (MOTIFS): a qualitative interview study

BackgroundThe novel Motor Imagery to Facilitate Sensorimotor Re-Learning (MOTIFS) training model, which began development in 2018, integrates psychological training into physical rehabilitation in knee-injured people.ObjectiveThis qualitative interview study aims to understand, interpret, and describe how physical therapists perceive using the MOTIFS Model.MethodsOne-on-one semi-structured intervi

Tests for the identification of reflex syncope mechanism

INTRODUCTION: Treatment efficacy of reflex syncope is mainly related to the mechanism underlying syncope rather than its etiology or clinical presentation. The predominant mechanism underlying reflex syncope can be assigned to hypotensive or to bradycardic phenotypes.AREAS COVERED: Methodology and diagnostic criteria of the most useful tests for the identification of hypotensive and bradycardic ph

Familial Associations of Complete Atrioventricular Block : A National Family Study in Sweden

BACKGROUND: Complete atrioventricular block (CAVB) is a major reason for implantation of permanent pacemakers, but knowledge of CAVB inheritance is sparse. This nationwide study aimed to determine the occurrence of CAVB in first-, second-, and third-degree relatives (full siblings, half-siblings, and cousins).METHODS: The Swedish multigeneration register was linked to the Swedish nationwide patien

Socioeconomic inequalities in musculoskeletal disorders outcomes and care. Educational inequalities in fracture-related mortality and osteoarthritis.

Musculoskeletal disorders (MSDs) are a major cause of disability worldwide, and two conditions that are major contributors to the overall burden of MSDs are fractures and osteoarthritis (OA). The Swedish Health and Medical Services Act (HSL 2017:30) states that the goal of all health care services is good health and health care on equal terms for the entire population. However, there exists a well