Quantitative reconstructions of past land cover are necessary to determine the processes involved in climate-human-land-cover interactions. We present the first temporally continuous and most spatially extensive pollen-based land-cover reconstruction for Europe over the Holocene (last 11g€¯700g€¯calg€¯yrg€¯BP). We describe how vegetation cover has been quantified from pollen records at a 11 spatia

Why do certain countries display high gender equalities while others display low gender equalities? To what extent does gender equality foster economic growth and development? The past decade has witnessed a boom and increasing literature about the role played by women and gender in long-run economic development. The increasing awareness of economics and economic history have contributed to improv

Timber buildings are intrinsically lightweight and hence can be susceptible to low-frequency vibrations and structure-borne noise. So, within the development of technical solutions for mitigating unwanted vibrations and noise, accurate and computationally efficient numerical models are considered to be of great value. Such models should take into account all physical phenomena that are relevant fo

In this paper we provide quenched central limit theorems, large deviation principles and local central limit theorems for random U(1) extensions of expanding maps on the torus. The results are obtained as special cases of corresponding theorems that we establish for abstract random dynamical systems. We do so by extending a recent spectral approach developed for quenched limit theorems for expandi

Robust autonomy stacks require tight integration of perception, motion planning, and control layers, but these layers often inadequately incorporate inherent perception and prediction uncertainties, either ignoring them altogether or making questionable assumptions of Gaussianity. Robots with nonlinear dynamics and complex sensing modalities operating in an uncertain environment demand more carefu

A triangular system of conservation laws with discontinuous flux that models the one-dimensional flow of two disperse phases through a continuous one is formulated. The triangularity arises from the distinction between a primary and a secondary disperse phase, where the movement of the primary disperse phase does not depend on the local volume fraction of the secondary one. A particular applicatio

Induction of SRY box transcription factor 9 (SOX9) has been shown to occur in response to kidney injury in rodents, where SOX9-positive cells proliferate and regenerate the proximal tubules of injured kidneys. Additionally, SOX9-positive cells demonstrate a capacity to differentiate toward other nephron segments. Here, we characterized the role of SOX9 in normal and injured human kidneys. SOX9 exp

Late Quaternary glaciations, deglaciations, sea-level changes and aeolian activity have resulted in an abundance of clastic sediments that currently cover the three Baltic States, Northern Europe almost entirely. The chronology for these deposits has largely been established from luminescence dating. This review synthesises 201 luminescence ages obtained between 2011 and 2021 on sediments in the B

Cancer prevalence and its rate of incidence are constantly rising since the past few decades. Owing to the toxicity of present-day antineoplastic drugs, it is imperative to explore safer and more effective molecules to combat and/or prevent this dreaded disease. Flavonoids, a class of polyphenols, have exhibited multifaceted implications against several diseases including cancer, without showing s

The specific viscoelastic mechanical properties of Achilles tendons are highly dependent on the structural characteristics of collagen at and between all hierarchical levels. Research has been conducted on the deformation mechanisms of positional tendons and single fibrils, but knowledge about the coupling between the whole tendon and nanoscale deformation mechanisms of more commonly injured energ

Older adults have been markedly impacted by the coronavirus disease 19 (COVID-19) pandemic, and many reports have cited concerns regarding potential psychiatric sequelae of coronavirus disease (COVID-19), but the actual effects of psychotropics on the COVID-19 are unclear. In this study, multivariate logistic regression was used to evaluate associations between the prescription of psychotropics an

Measuring the concentration of alcohol (ethanol) in exhaled breath (BrAC) provides a rapid and non-invasive way to determine the co-existing concentration in arterial blood (A-BAC). The results of breath-alcohol testing are used worldwide as evidence of excessive drinking, such as when traffic offenders are prosecuted. Two types of breath-alcohol analyzer are in common use; hand-held instruments u

Motivation: Most protein-structure superimposition tools consider only Cartesian coordinates. Yet, much of biology happens on the surface of proteins, which is why proteins with shared ancestry and similar function often have comparable surface shapes. Superposition of proteins based on surface shape can enable comparison of highly divergent proteins, identify convergent evolution and enable detai

Bertrand Russell’s speech “Why I Am Not a Christian” (1927) triggered many theologians to defend Christian beliefs. Aside from his rational criticism of the so-called “proofs” of God’s existence, it is his humorous irony as a rhetorical weapon that made many abandon their faith in Christianity and become atheists or at least agnostics. In this article I examine two British theologians’ unsuccessfu

The article offers a historical approach to one of the most understudied areas of international humanitarian law by focusing on the successes and shortfalls of the two international armed conflicts with the highest numbers of civilians interned in global history. Through the study of State practice during Word War I and Word War II, the author addresses the causes and justifications that led to ma

Lymphedema negatively impacts patients’ quality of life, both physiologically and psychologically. Lymph stasis and inflammation result in excess formation of adipose tissue, which makes removal of the deposited subcutaneous fat necessary to eliminate the excess volume. Liposuction, combined with postoperative controlled compression therapy, is the only treatment that gives complete reduction of t

Chronic and acute lung diseases are the third and fourth leading causes of global mortality. Distal lung tissue is severely damaged in many lung diseases, causing respiratory insufficiency from loss of surface area available for gas exchange. Current therapies aim at relieving symptoms and are unable to reverse disease. Lung transplantation remains the only potential curative option at end-stage d