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Searching for Celiac Disease Screening-detected celiac disease in an HLA-genotyped birth cohort
Popular Abstract in Swedish Celiaki, även kallat glutenintolerans, är en tarminflammation orsakad av vissa sädesslag i kosten och förekommer hos både barn och vuxna. Sjukdomen drabbar ca 1% av befolkningen i västvärlden och betraktas som en av de vanligaste kroniska sjukdomarna bland svenska barn. Många individer med sjukdomen är oupptäckta och kan bara hittas via s.k. screening, d.v.s. att man leObjectives: Celiac disease is a common immune mediated enteropathy strongly associated with HLA-DQB1*02 (DQ2), *0302 (DQ8), or both and the presence of tissue transglutaminase autoantibodies (tTGA). Prevalence studies have revealed that most affected individuals go undetected because of subclinical signs or being asymptomatic rendering screening a method for identification. However, less is known
A thermostable phytase from Bacillus sp. MD2: cloning, expression and high-level production in Escherichia coli.
Phytase is used as a feed additive for degradation of antinutritional phytate, and the enzyme is desired to be highly thermostable for it to withstand feed formulation conditions. A Bacillus sp. MD2 showing phytase activity was isolated, and the phytase encoding gene was cloned and expressed in Escherichia coli. The recombinant phytase exhibited high stability at temperatures up to 100 degrees C.
Legal Deposit in Denmark over three hundred Years
Generalization of n-ary Nambu algebras and beyond
The aim of this paper is to introduce n-ary Hom-algebra structures generalizing the n-ary algebras of Lie type including n-ary Nambu algebras, n-ary Nambu-Lie algebras and n-ary Lie algebras, and n-ary algebras of associative type including n-ary totally associative and n-ary partially associative algebras. We provide examples of the new structures and present some properties and construction theo
Klusterhuvudvärk kan vara förknippad med bakomliggande sjukdom.
Interplay between BRCA1 and RHAMM Regulates Epithelial Apicobasal Polarization and May Influence Risk of Breast Cancer
Differentiated mammary epithelium shows apicobasal polarity, and loss of tissue organization is an early hallmark of breast carcinogenesis. In BRCA1 mutation carriers, accumulation of stem and progenitor cells in normal breast tissue and increased risk of developing tumors of basal-like type suggest that BRCA1 regulates stem/progenitor cell proliferation and differentiation. However, the function
Leadership Across Boundaries
Altered Expression of Metallothionein-I and -II and Their Receptor Megalin in Inherited Photoreceptor Degeneration
PURPOSE. To examine in rodent models of retinitis pigmentosa (RP) the expression of the neuroprotectants metallothionein-I and -II and of megalin, an endocytic receptor that mediates their transport into neurons. METHODS. Gene and protein expression were analyzed in retinas of rd1 and rds mice and in those of RCS (Royal College of Surgeons) rats of various ages. Glial cell markers (cellular retina
Minimising activity and dose with enhanced image quality by radiopharmaceutical administrations
Owing to the introduction of new diagnostic procedures, such as computed tomography (CT), positron emission tomography (PET) and single photon emission computed tomography (SPECT), the individual dose caused by medical exposures has grown rapidly in the last years. This is especially a subject to radiation protection for nuclear medical diagnosis, since in this case radiopharmaceuticals are admini
Synthesising intonational varieties of Swedish
Theropod dinosaur teeth from the lowermost Cretaceous Rabekke Formation on Bornholm, Denmark
The dinosaur fauna of the palynologically dated lower Berriasian Skyttegard Member of the Rabekke Formation on the Baltic island of Bornholm, Denmark, is represented by isolated tooth crowns. The assemblage is restricted to small maniraptoran theropods, assigned to the Dromaeosauridae incertae sedis and Maniraptora incertae sedis. The dromaeosaurid teeth are characterized by their labiolingually c
Coulomb Excitation of 68Ni at "safe" energies
The B(E2;0+2+) value in 68Ni has been measured using Coulomb excitation at safe energies. The 68Ni radioactive beam was postaccelerated at the CERN on-line isotope mass separator (ISOLDE) facility to 2.9 MeV/u and directed to a 108Pd target. The emitted rays were detected by the MINIBALL detector array. Not only directly registered but also indirectly deduced information on the nucleus emitting th
How can Open Source Software Development Help Requirements Management Gain the Potential of Open Innovation: An Exploratory Study
A key component in successfully managing software products is to properly, and in a timely manner, identify and secure competitive advantage by innovation via feature differentiation. Although open source software (OSS) is not a new idea, several product development companies that operate in a market-driven context have started to use open source solutions as core software components in their prod
Why Common Sense Will Not Take Us Far When Making a Better World
In this article it is argued that common sense morality in many cases leads to suboptimal consequences and that human beings in general put too much faith in their moral intuitions. In the first section an explanation of common sense moral is offered. In the second section a working definition of “better world” is presented. In section three, contemporary psychological research concerning human mo
Relationship between postprandial changes in cardiac left ventricular function, glucose and insulin concentrations, gastric emptying, and satiety in healthy subjects
Background: The digestion of food is known to alter the hemodynamics of the body significantly. The purpose of this study was to study the postprandial changes in stroke volume (SV), cardiac output (CO) and left ventricular (LV) longitudinal systolic and diastolic functions measured with tissue Doppler imaging, in relation to gastric emptying rate (GER), satiety, and glucose and insulin concentrat
Evaluation of Different Treatments for Appendiceal Abscess in Children
Introduction: Despite the high incidence of appendicitis, the diagnosis is often delayed in children. A delayed diagnosis may lead to perforation and formation of an abscess. The treatment of an appendiceal abscess is still a debatable subject and studies have not agreed on what strategy to use. Some prefer immediate operation, whereas others advocate conservative management with or without interv
Travels to Identity – Viking Rune Carvers of Today
This text deals with the phenomenon of today’s rune carvers in the Nordic area. By using symbols of antiquity in their craftsmanship, the rune carvers revive an act that is historically significant and bears aspects of identity in the past as well as today. Why do people carve and erect runes stones today? When and where is it done? What are the explicit or implicit purposes? The text tries to ans
Substratum-dependent responses of ciliate assemblages to temperature: a natural experiment in Icelandic streams
Ciliate assemblages play a significant role in the microbial food web. The effects of environmental temperature on assemblage composition may be influenced by abiotic factors such as seasonality and disturbance, but the effects of temperature on ciliate assemblages found on different substrata have not been explored. Sandy bottoms and submerged rocks harbour dissimilar ciliate assemblages, and it
Närgånget om svensk underrättelsetjänst
Recension av Sam Nilsson, T-kontoret. Underrättelsetjänst och västsamarbete.