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Frequentist versus Bayesian approaches to multiple testing

Published 19 June 2019 Multiple tests arise frequently in epidemiologic research. However, the issue of multiplicity adjustment is surrounded by confusion and controversy, and there is no uniform agreement on whether or when adjustment is warranted. In this paper we compare frequentist and Bayesian frameworks for multiple testing. New publication in European Journal of Epidemiology.Read more here.

https://www.lupop.lu.se/article/frequentist-versus-bayesian-approaches-multiple-testing - 2025-01-10

United States Pulmonary Hypertension Scientific Registry (USPHSR): rationale, design, and clinical implications

Published 20 June 2019 Diagnostic World Health Organization (WHO) Group 1 pulmonary arterial hypertension (PAH) and Diagnostic Group 1' pulmonary veno-occlusive disease (PVOD) and/or pulmonary capillary hemangiomatosis (PCH) are progressive and fatal disorders. Past registries provided important insights into these disorders, but did not include hormonal exposures or genomic data. New publication

https://www.lupop.lu.se/article/united-states-pulmonary-hypertension-scientific-registry-usphsr-rationale-design-and-clinical - 2025-01-10

Lund Population Day 2019

Published 20 June 2019 Centre for Economic Demography (CED) & Lund University Population Research Platform (LUPOP) is presenting the 2nd Lund Population Day 26 September 2019! Keynote speaker Tomas Sobotka will give an open lecture in the morning, and joining Sobotka are invited researchers of reproduction, both external and from Lund University, who will present shorter lectures in the afternoon.

https://www.lupop.lu.se/article/lund-population-day-2019 - 2025-01-10

How to measure temporal changes in care pathways for chronic diseases using health care registry data

Published 25 June 2019 Disease trajectories for chronic diseases can span over several decades, with several time-dependent factors affecting treatment decisions. Thus, there is a need for long-term predictions of disease trajectories to inform patients and healthcare professionals on the long-term outcomes and provide information on the need of future health care. New publication in BMC Medical I

https://www.lupop.lu.se/article/how-measure-temporal-changes-care-pathways-chronic-diseases-using-health-care-registry-data - 2025-01-10

Smoking-induced risk of future cardiovascular disease is partly mediated by cadmium in tobacco: Malmö Diet and Cancer Cohort Study.

Published 27 June 2019 Smoking is a strong risk factor for cardiovascular disease (CVD) and causes exposure to cadmium, which is a pro-atherosclerotic metal. Cadmium exposure has also been shown to increase the risk of CVD, even after adjustment for smoking. Our hypothesis was that part of the risk of CVD in smokers may be mediated by cadmium exposure from tobacco smoke. We examined this hypothesi

https://www.lupop.lu.se/article/smoking-induced-risk-future-cardiovascular-disease-partly-mediated-cadmium-tobacco-malmo-diet-and - 2025-01-10

Causal Mediation Analysis for Standardized Mortality Ratios

Published 1 July 2019 Indirectly standardized mortality ratios (SMR) are often used to compare patient outcomes between health care providers as indicators of quality of care. Observed differences in the outcomes raise the question of whether these could be causally attributable to earlier processes or outcomes in the pathway of care that the patients received. Such pathways can be naturally addre

https://www.lupop.lu.se/article/causal-mediation-analysis-standardized-mortality-ratios - 2025-01-10

LUPOP

Published 18 August 2017 Cohort- and register-based research LUPOP – Lund University Population Research Platform – was initiated in 2017 in order to promote and strengthen research using individual-level data linked with registers. LUPOP is an open source available for all researchers at Lund University, irrespective of faculty. A main purpose of LUPOP is to collect, maintain and disseminate info

https://www.lupop.lu.se/article/lupop - 2025-01-10

The development of spasticity with age in 4,162 children with cerebral palsy: a register-based prospective cohort study

Published 8 July 2019 Spasticity is often regarded as a major cause of functional limitation in children with cerebral palsy (CP). We analyzed the spasticity development with age in the gastrosoleus muscle in children with CP. New publication in Acta Prthopaedica.Read more here.

https://www.lupop.lu.se/article/development-spasticity-age-4162-children-cerebral-palsy-register-based-prospective-cohort-study - 2025-01-10

[26 Years of the Erlangen Glaucoma Registry: Demographic and Perimetric Characteristics of Patients Through the Ages].

Published 10 July 2019 The history of the Erlangen Glaucoma Registry goes back 26 years. In this study, we present retrospective demographic and perimetric data on the initial visit of patients with ocular hypertension (OHT), pre-perimetric (prePOAG) and perimetric primary open-angle glaucoma (POAG), normal tension glaucoma (NTG) and secondary open-angle glaucoma (SOAG) and correlate these results

https://www.lupop.lu.se/article/26-years-erlangen-glaucoma-registry-demographic-and-perimetric-characteristics-patients-through-ages - 2025-01-10