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The Italian Sarcoma Group and the Scandinavian Sarcoma Group designed a joint study to improve the prognosis for patients with Ewing's family tumors and synchronous metastatic disease limited to the lungs, or the pleura, or a single bone. The study was opened in 1999 and closed to the enrollment in 2008. The program consisted of intensive five-drug combination chemotherapy, surgery and/or radiothe

To determine the reliability and validity of a previously identified "suicide cluster" in the Percept-genetic Object-Relation Test (PORT), which test documents subliminal perception of object-relation pictures, 20 suicide attempters and 70 controls were investigated. The correspondence between scores assigned by two judges was 95%-100%. The suicide-cluster signs in PORT, notably "lack of attachmen

Boronate-containing thin polyacrylamide gels (B-Gel), polymer brushes (B-Brush) and chemisorbed organosilane layers (B-COSL) were prepared on the surface of glass slides and studied as substrates for carbohydrate-mediated cell adhesion. B-COSL- and B-Brush-modified glass samples exhibited multiple submicron structures densely and irregularly distributed on the glass surface, as found by scanning e

Different strategies for obtaining nanowires (NWs) with ferromagnetic properties using the molecular beam epitaxy (MBE) grown nanostructures combining GaAs and Mn were investigated. Four types of structures have been studied: (i) self-catalyzed GaAs: Mn NWs grown at low temperatures on GaAs(100) substrates; (ii) GaAs: Mn NWs grown at high temperatures on Si(100) substrates; (iii) GaAs-GaMnAs core-

One of the central tasks of EUFORIA is to port, parallelise, and optimise fusion simulation codes, developed at individual research institutes in Europe. There are three supercomputer centres involved in the project located at Barcelona, Edinburgh, and Helsinki. For some of the fusion codes simply porting them to one of the supercomputers represents a major advancement in the use of the codes, as

We report the first experiments carried out on a new imaging setup, which combines the high spatial resolution of a photoemission electron microscope (PEEM) with the temporal resolution of extreme ultraviolet (XUV) attosecond pulse trains. The very short pulses were provided by high-harmonic generation and used to illuminate lithographic structures and Au nanoparticles, which, in turn, were imaged

Alkaline hydrolysis of polymers produces heat that can be measured with isothermal calorimetry to monitor the hydrolysis. We here report on two studies to measure the enthalpy of alkaline hydrolysis of polymers containing esters of carboxylic acids. The heat from the hydrolysis of films of poly(vinyl acetate), PVAc, was followed for up to 42 days and correlated with the amounts of acetic acid prod

Alignment between business strategy and information strategy has been focused on for several years with research suggesting different explanations to how this alignment influences a firm's performance. This article presents results from an investigation of firms in Slovenia about how business people perceived their business strategy and information strategy to be aligned. Respondents? statements f

Prepulse is a major issue for laser generation of protons, often limiting the performances of laser sources. Here, we show the use of prepulse (1013W/cm2, ns duration) to actively manipulate the proton beam direction. Under oblique high-intensity irradiation (approximate to 1019W/cm2, ps duration) of the thin foil target, and for low prepulse intensities, the proton beam is directed away from the

Recension av Bengt Liljegren, Winston Churchill, del 2: 1939–1965.

Recension av Anna Bikont, Vi från Jedwabne.

Popular Abstract in English According to the International Diabetes Federation (IDF), 415 million people suffer from diabetes worldwide. Diabetes occurs when the pancreatic beta cells are no longer able to produce or properly use insulin. Insulin regulates blood glucose levels by enabling glucose uptake into cells, providing the body with energy. Elevated glucose levels cause damages to highly vasDiabetes mellitus is metabolic disorder caused by a defect or lack of beta cell-produced insulin that controls blood glucose homeostasis. In addition to glucose, insulin secretion is regulated by the autonomic nervous system (ANS); the neurotransmitter acetylcholine as well as monoamines, such as dopamine, serotonin, melatonin and norepinephrine. Using a MafA mutant mouse model, we show that MafA

Experiments performed with the high-contrast 0.7-J 35-fs Ti:sapphire laser at the Lund Laser Centre focused into a helium gas jet have produced quasi-monoenergetic electron beams with energies up to 150 MeV. The beam is produced as a result of controlled wavebreaking of a wakefield generated by the relativistically channeled laser beam. Under the best conditions of laser energy and plasma density,

Human monocytes are a heterogeneous cell population classified into three different subsets: Classical CD14++CD16-, intermediate CD14++CD16+, and non-classical CD14+CD16++ monocytes. These subsets are distinguished by their differential expression of CD14 and CD16, and unique gene expression profile. So far, the variation in inter-cellular gene expression within the monocyte subsets is largely unk

In this study we investigated the potential neuroprotective effect of 2-oxoglutarate (2-OG) on the hippocampus in the transient vessel occlusion ischemia model in the Mongolian gerbil. The morphological and biochemical studies were performed at 7 days after occlusion of carotid arteries. The acute reduction of NeuN-positive neurons in the CA1 pyramidal layer of the hippocampus was accompanied by i

Since their discovery more than 70 years ago antibiotic drugs have been efficient tools for treating bacterial infections, and their use has reduced the number of fatalities and the suffering from bacterial diseases. However, the use of antibiotics may lead to resistance to the same or other antibiotics. The risk of resistance appears to be larger in veterinary medicine, since antibiotics have bee

The article discusses the identity, roles, and duties of the professional historian in an era in which the historical dimension is no longer a historian's monopoly. It is argued that the standard modern framework of understanding a historian as someone highly specialized in the production of 'new' history has to give way to a new understanding that situates the historian in historical culture, whi