Published 8 October 2019 Clinical research is the study of aspects of patient health or illness that are closely related to clinical practice. In the late 20th and early 21th century, outcomes for patients with rheumatoid arthritis (RA) improved dramatically due to breakthroughs in new drugs. Patient-reported outcome measures now play a significant role in the drug development process as study end

https://www.lupop.lu.se/article/paradigm-shift-studies-based-rheumatoid-arthritis-clinical-registries - 2025-02-10

Published 9 October 2019 The least biased censoring strategy for time-to-event analyses in the presence of LTFU depends on the event and estimand of interest. New publication in Epidemiology.Read more here.

https://www.lupop.lu.se/article/censoring-loss-follow-time-event-analyses-composite-outcomes-or-presence-competing-risks - 2025-02-10

Published 10 October 2019 Pitfalls were identified in 2 major areas—design and data analysis. Design pitfalls included unbalanced cohorts, uncontrolled covariates, and flawed oncologic variables. Analytical pitfalls included incorrect application of univariate analyses, inclusion of inaccurate data, and inclusion of stage IVc disease in curative survival analysis. Additional limitations of databas

https://www.lupop.lu.se/article/common-pitfalls-head-and-neck-research-using-cancer-registries - 2025-02-10

Published 11 October 2019 Carriers of haemophilia suffer a significant risk for joint comorbidities. This risk seems to correlate to the factor activity. Our findings underline the impor‐tance of regular clinical follow‐up of carriers at HTCs. New publication in Wiley.Read more here.

https://www.lupop.lu.se/article/joint-comorbidities-among-swedish-carriers-haemophilia-register-based-cohort-study-over-22-years - 2025-02-10

Published 21 October 2019 Enzalutamide can be used to effectively treat mCRPC patients in daily clinical settings, despite the patients being older and less healthy than those enrolled in the previous randomised, clinical registration studies. Read the full paper here.

https://www.lupop.lu.se/article/registry-based-study-evaluating-overall-survival-and-treatment-duration-swedish-patients-metastatic - 2025-02-10

Published 22 October 2019 Incidence, patient characteristics and risk of revision Read the full paper here.

https://www.lupop.lu.se/article/manipulation-under-anesthesia-after-primary-knee-arthroplasty-sweden - 2025-02-10

Published 23 October 2019 Results from a Swedish community-based cohort study Read the full paper here.

https://www.lupop.lu.se/article/use-anthropometric-measures-prediction-incident-gout - 2025-02-10

Published 24 October 2019 A cohort study from Ronneby, Sweden Read the full paper here.

https://www.lupop.lu.se/article/high-exposure-perfluorinated-compounds-drinking-water-and-thyroid-disease - 2025-02-10

Published 25 October 2019 The current study supports the usage of gene expression signatures in specific clinical treatment groups within population-based breast cancer. It also stresses the need of further development to reach higher consensus in individual patient classifications, especially for intermediate-risk patients, and the targeting of patients where current gene signatures and prognosti

https://www.lupop.lu.se/article/cross-comparison-and-prognostic-assessment-breast-cancer-multigene-signatures-large-population-based - 2025-02-10

Published 26 October 2019 This article describes how central cancer registries can provide a population-based sample frame that will lead to studies with strong external validity, how central cancer registries can link with public and private health insurance claims to obtain complete treatment information, how central cancer registries can use informatics techniques to provide population-based ra

https://www.lupop.lu.se/article/unlocking-potential-population-based-cancer-registries - 2025-02-10

Published 27 October 2019 Report on a nationwide, population‐based register with transparent reporting of data on the performance of radical prostatectomy. These data are needed as a basis for quality assurance with comparisons of results from individual surgeons and hospitals. Read the full paper here.

https://www.lupop.lu.se/article/population-based-nationwide-registration-ofprostatectomies-sweden - 2025-02-10

Published 28 October 2019 This study showed a high adherence with treatment with statins among colorectal cancer patients. Read the full paper here.

https://www.lupop.lu.se/article/validating-registry-data-statins-prescriptions-bloodmeasurements - 2025-02-10

Published 29 October 2019 The Pregnancy Register offers huge research potential because of its large size, high completeness, and availability. Further validation work is underway to enhance this data resource and identify optimal approaches for its use. Read the full paper here.

https://www.lupop.lu.se/article/methods-generate-and-validate-pregnancy-register-theuk-clinical-practice-research-datalink-primary - 2025-02-10

Published 30 October 2019 Noninterventionist prospective multicentre international Registry pro‐moted by the European Helicobacter and Microbiota Study Group. National Coordinators will select recruiting gastroenterologists in their country that will register the H pylori‐related routine clinical practice consultations they receive in an electronic case report form (e‐CRF) provided by AEG‐REDCa Re

https://www.lupop.lu.se/article/protocol-european-registry-management-helicobacter-pylori-infection-hp-eureg - 2025-02-10

Published 31 October 2019 The World Health Organization(WHO) and many other public health agencies recommend that pregnant women be vaccinated annually against influenza. Read the full text here.

https://www.lupop.lu.se/article/power-registry-studies-inform-maternal-influenzavaccine-policy-and-practice - 2025-02-10

Published 9 October 2019 Artificiell intelligens (AI) och maskinlärning är heta områden inom hälso- och sjukvården. Genom att bearbeta stora datamängder kan självlärande datorprogram upptäcka komplexa samband hos patienter, hitta tidiga markörer för sjukdom och ställa mer korrekta diagnoser. Men med den nya tekniken kommer även risker. Ett tvärvetenskapligt forskningsprojekt vid bland annat Lunds

https://www.lupop.lu.se/article/forskare-ska-undersoka-hur-sjalvlarande-datorprogram-kan-ge-battre-vard - 2025-02-10

Published 12 October 2019 The PhD position is tied to a research project on ”Developmenal origins of women’s health”. The research project aims to investigate early life determinants of major health, reproductive and social outcomes in adulthood and their interactions over the life course, with a particular focus on gender differences and women’s health. This includes e.g. in depth investigations

https://www.lupop.lu.se/article/phd-student-public-health-sciences-focus-social-epidemiology - 2025-02-10

Published 13 October 2019 The MISS study comprises register data, questionnaire data, and biological samples from 29,600 women aged 25-65 years in 1990. Read more here.

https://www.lupop.lu.se/article/miss-study - 2025-02-10

Published 14 October 2019 The healthcare value of Australian clinical quality registries (CQRs) has recently been highlighted by the Australian Commission of Safety and Quality in Health Care (ACSQHC) as being similar to the benefits of CQRs reported internationally. New publication in Australian Health Review.Read more here

https://www.lupop.lu.se/article/towards-strategy-clinical-quality-registries-australia - 2025-02-10

Published 15 October 2019 Future research on health inequality relies on data that cover life-course exposure, different birth cohorts and variation in policy contexts. Nordic register data have long been celebrated as a ‘gold mine’ for research, and fulfil many of these criteria. However, access to and use of such data are hampered by a number of hurdles and bottlenecks. New publication in Scandi

https://www.lupop.lu.se/article/gold-mine-still-no-klondike-nordic-register-data-health-inequalities-research - 2025-02-10