Popular Abstract in Swedish Wilms tumör gen 1 (WT1) i normal blodbildning och vid akut leukemi Blodet innehåller en mängd olika celltyper som var och en har sin specifika funktion. De röda blodkropparna transporterar syre till kroppens alla vävnader, de vita blodkropparna skyddar mot olika typer av infektioner och blodplättarna är viktiga för blodkoagulering och sårläkning. Eftersom de mogna blodWilms’ tumor gene 1 (WT1) is a zinc-finger transcription factor that is involved in the development of urogenital organs and mesothelial tissues. It was initially identified as a tumor suppressor gene, based on the observation that somatic inactivation of the gene predispose for development of the pediatric kidney cancer Wilms’ tumor. A role for WT1 in hematopoiesis was suggested based on the fact

The enzymatic degradation of wood polysaccharides such as cellulose and hemicellulose is an important process in nature. In addition, cellulases and hemicellulases can be used in industrial applications. Fuel ethanol can potentially be produced from wood by enzymatic hydrolysis of cellulose followed by yeast fermentation of the formed sugars. In this thesis, fungal glycoside hydrolases, cellulase

This thesis investigates ruin probabilities and first passage times for self-similar processes. We propose self-similar processes as a risk model with claims appearing in good and bad periods. Then, in particular, we get the fractional Brownian motion with drift as a limit risk process. Some bounds and asymptotics for ruin probability on a finite interval for fractional Brownian motion are derive

The article investigates new archive material shedding light on the intricate development of European freemasonry in East Asia during the Eighteenth century.

Code inspections and white-box testing have both been used for unit testing. One is a static analysis technique, the other, a dynamic one, since it is based on executing test cases. Naturally, the question arises whether one is superior to the other, or, whether either technique is better suited to detect or isolate certain types of defects. We investigated this question with an experiment with a

The main ambition of companies is to deliver products (or services) to customers successfully in order to remain competitive. This requires an efficient and effective product development process, as well as cost reductions and higher service levels through improved logistics performance in the supply chain. Traditionally, these two areas, i.e. product development and logistics, have been treated s

Abstract PTSD or Post Traumatic Stress Disorder (or, earlier, Syndrome) covers a great variety of symptoms which develop in a variety of contexts – accidents, natural disasters, terrorist attacks, wars and other events where people come face to face with violence and death. PTSD was included in the third edition of the Diagnostic and Statistical Manual of Mental Disorders, DSM-III, during the earl

Popular Abstract in Swedish Insekter kommunicerar med dofter. De artspecifika kemiska substanser som används mellan individer kallas feromoner. Hos sädesbroddflyet, Agrotis segetum, producerar honan en "parfym", ett sexualferomon som består av flera komponenter, för att locka till sig en hane. På hanens antenner finns lukthår med särskilda motagare, receptorer, som används för att detektera honansA number of analogues of (Z)-5-decenyl acetate (1), a pheromone component of the turnip moth, Agrotis segetum, have been synthesised and tested by using single-cell electrophysiology, in order to investigate the relationships between structure and activity, and to elucidate the interactions between 1 and its receptor. Molecular mechanics and ab initio quantum mechanical calculations have been used

Resistivity imaging in combination with drill hole information is a powerful tool in geotechnical site investigations. Traditionally the resistivity data is inverted with a 2D smooth inversion algorithm, resulting in a minimum structure model. In the geological interpretation it can be difficult to determine sharp layer boundaries in these models. An additional parameterized inversion of resistivi

This thesis describes the affinity and enantiomeric selectivity of the cellobiohydrolase Cel7A (isolated from Hypocrea jercorina). The chiral recognition of the enzyme has been studied with respect to amino alcohols and new ligands have been designed, based on the structure of the common ?-blocker propranolol. Capillary electrophoresis have been used to determine the dissociation constants of the

The consolidation of paper during drying is of interest to increase the understanding of the development of the paper quality. The mercury displacement technique proved suitable to measure the apparent solid density and the volume fractions of solid, liquid and gas in wet paper sheets. Measurements were performed on handsheets of chemi-thermomechanical pulp (CTMP), bleached and unbleached softwood

Popular Abstract in Swedish Stokastika effekter är av stor betydelse i många biofysiska system. Evolution, djurs sökande efter föda, spridning av virusinfektioner och stamcellsdifferentiering, är alla exempel på processer som på ett eller annat sätt är stokastiska till sin natur. Syftet med denna avhandling är att undersöka de verktyg som ofta används för att kvantifiera slumpmässighet i naturen oThe role of stochasticity throughout many biophysical systems is of great importance. From evolution to foraging, from the spreading of viruses to cell fate, all hinge in one way or another on inherent stochasticity. The aim of this thesis is to explore the tools often used to quantify randomness in nature, and employ these tools on a selected range of biophysical systems (Papers I-IV). In these p

Since May 1998 Scandinavian group researchers and social psychologists have met bi-annually for what has to be called the GRASP conference. GRASP originally stood for ”Group as Paradox”. The first five conferences were held in Linköping, Lund, Stockholm and Skövde and, again, Linköping. The sixth conference was organized at Lund University May 15-16, 2008 under the auspices of the network Organi

Popular Abstract in Swedish Växters fenologi påverkar ekosystemens funktion och tjänster, och återkopplar till klimatet genom att påverka utbytet av kol, vatten och energi mellan atmosfär och ekosystem. Under de senaste decennierna har växternas fenologi studerats i allt större omfattning, men fortfarande är osäkerheten stor och enighet saknas om klimatets inverkan på fenologi och förändringar övePlant phenology exerts major influences on carbon, water, and energy exchanges between atmosphere and ecosystems, provides feedbacks to climate, and affects ecosystem functioning and services. Great efforts have been spent in studying plant phenology over the past decades, but there are still large uncertainties and disputations in phenology estimation, trends, and its climate sensitivities. This

Revisiting Parsons' 1996 article about disability insurance with imperfect tagging in a two type-economy -- individuals are either able or disabled. Here Parsons' analysis is extended in several directions. The model is generalized to allow for different utility functions over work status. The analysis extends to three different cases of a two-type economy. Finally Parsons' model is extended to th