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Effects of simvastatin on circulating autoantibodies to oxidized LDL antigens: relation with immune stimulation markers.

Statins exert a number of anti-inflammatory and immunomodulatory effects in vitro. However, the immunomodulatory effects in vivo are less clarified. In the present study, we investigated whether simvastatin treatment changed the levels of autoantibodies against specific oxidized LDL (oxLDL) antigens as well as their association with leukocyte activation markers. Eighty volunteers with mild-to-mode

Sources and Diagnostics for Attosecond Science

Popular Abstract in English What is a photographic camera flash good for? The easy answer is “to illuminate”. There is more to it though: the duration of a camera flash is usually much shorter than the shutter speed of the camera. This allows us to take sharp pictures of fast objects with an inexpensive camera. Ultrafast science is based on a similar principle: no shutter is capable of opening andUltrafast science refers to physical events that happen on the femtosecond (1 fs=10^-15 s) and attosecond (1 as=10^-18 s) timescales. Generation of attosecond pulses is usually achieved by interacting high-intensity femtosecond pulses with matter (typically gases), in a process called high-order harmonic generation (HHG). Under the correct conditions, this process leads to the creation of sub-fs p

Changes in GAD65Ab-Specific Antiidiotypic Antibody Levels Correlate with Changes in C-Peptide Levels and Progression to Islet Cell Autoimmunity.

Context: The previously reported absence of 65-kDa glutamate decarboxylase antibody (GAD65Ab)-specific antiidiotypic antibodies (anti-Id) in type 1 diabetes (T1D) patients at clinical onset could be due to an inability to mount an antibody response to GAD65Ab or a longitudinal decline in anti-Id levels. Objective and Design: We investigated anti-Id levels in longitudinal samples obtained from T1D

Costs and quality of life for psoriatic patients at different degrees of severity in southern Sweden - a cross-sectional study.

Objectives: Knowledge of the societal costs of psoriasis is limited. This study estimated the cost of care, psoriasis area and severity index (PASI), and quality of life in a defined patient population in Sweden. Methods: A prevalence-based prospective recruitment of patients visiting two Swedish dermatology clinics between September and December 2009 was performed, collecting resource utilization

Anime

Kulturartikel om japansk animerad film, anime.

En styrkefilosof fylld av oro

Erlander var enligt Ruin en politisk bedömare som mer influerades av den egna oron än av det faktiska läget. Oron präglade också hans beslutssituationer. Erlanders politiska doktrin har kallats "det starka samhället" och innebär att staten skulle skapa och garantera människors trygghet. Denna doktrin krävde starka regeringar med brett underlag i riksdagen. Ruin kallar doktrinen för en styrkefiloso

Dentin formation after corticosteroid treatment. A clinical study and an experimental study on rats

The overall aim of this series of studies was to determine whether the extensive narrowing of the dental pulp chamber seen in dental radiographs of patients with end stage renal disease was related to the method of treatment of the renal disease. The treatments studied were immunosuppression, renal transplantation and hemodialysis. A strong correlation was found between narrowing of the dental pul