Milk protein intake has recently been suggested to improve metabolic health. This Perspective provides evidence that metabolic effects of milk protein intake have to be regarded in the context of the individual's pre-existing metabolic and exercise status. Milk proteins provide abundant branched-chain amino acids (BCAAs) and glutamine. Plasma BCAAs and glutamine are increased in obesity and insuli

Rational drug design is predicated on knowledge of the three-dimensional structure of the protein-ligand complex and the thermodynamics of ligand binding. Despite the fundamental importance of both enthalpy and entropy in driving ligand binding, the role of conformational entropy is rarely addressed in drug design. In this work, we have probed the conformational entropy and its relative contributi

Abstract in UndeterminedInside a tunnel, electromagnetic wave propagation differs strongly from the well understood "open-air" situation. The characterization of the tunnel environment is crucial for deploying vehicular communication systems. In this paper we evaluate vehicle-to-vehicle (V2V) radio channel measurements inside a tunnel. We estimate the time-varying root mean square (rms) delay and

Background: Since barrier protection measures to avoid contact with allergens are being increasingly developed, we assessed the clinical efficacy and tolerability of a topical nasal microemulsion made of glycerol esters in patients with allergic rhinitis. Methods: Randomized, controlled, double-blind, parallel group, multicentre, multinational clinical trial in which adult patients with allergic r

Flow-pattern based heat transfer correlations for elongated bubbly flow and annular flow in stable flow boiling micro/minichannels were developed separately based on a collected micro/minichannel heat-transfer database by using an improved conventional-to-micro/minichannel threshold Bo = 4 and BoRel0.5 = 200, where Bo is the Bond number and Rel is the liquid Reynolds number. As significant disagre

This study traces the history of publishers’ cloth-bindings in Sweden, and places them in relation to the emergence of modernity. The interaction between techno-logy, economics and aesthetics is central to the analysis, in which a sociological approach is combined with per-spectives of book history and material culture studies. • The study consists of two parts: Book culture in transit-ion, mainly

Due to increased awareness of climate change and higher energy costs, well‐insulated buildings have become more common. Furthermore, the interests of using wood in building to produce more carbon dioxide‐efficient houses have increased. However, thicker thermal insulation in walls increases the risk of high relative humidity levels and the risk of mould‐related damage in Wood frame houses. In orde

Physical activity and healthcare utilization has negative association. However, there appears to be limited knowledge of how this association is affected by self-rated health (SRH) and socio-economic status (SES). Therefore, the aim of this study was to examine the association between leisure-time physical activity (LTPA) and healthcare utilization, and investigate how SRH, gender, age and SES aff

One of the more fascinating phenomena in nature is animal mass migrations and in oceans and freshwaters, diel variations in depth distribution of zooplankton are a phenomenon that has intrigued scientists for more than a century. In our study, we show that zooplankton are able to assess the threat level of ultraviolet radiation and adjust their depth distribution to this level at a very fine tuned

Popular Abstract in Swedish Bakgrund Den kroniska ögonsjukdomen grön starr (glaukom) skadar ögats synnerv och påverkar den perifera synen (synfältet) hos de som drabbas. I västvärlden är grön starr den näst vanligaste orsaken till blindhet enligt Världshälsoorganisationen WHO. I Sverige räknar man med att cirka 70 000 personer över 70 år har grön starr, men att endast hälften av dessa är kända förThis thesis addresses several aspects of glaucoma diagnostics from both a clinical and a screening perspective. New instruments for diagnosing glaucoma have been developed over the past years, but little information is available regarding their performance as screening methods and their usefulness in ordinary clinical practice. Purpose of the research underlying this thesis The objectives of the

In this paper we present a systematic study of the morphology and composition of supported lipid bilayers (SLBs) formed by vesicle fusion using a wide variety of surface sensitive techniques that give information about the lateral as well as vertical structure and bilayer fluidity. SLBs of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) and 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC

The energy extraction efficiency is a figure of merit for a free-electron laser (FEL). It can be enhanced by the technique of undulator tapering, which enables the sustained growth of radiation power beyond the initial saturation point. In the development of a single-pass x-ray FEL, it is important to exploit the full potential of this technique and optimize the taper profile aw(z). Our approach t

Traces of Danish-Norwegian Church life in South and Western Sweden did not disappear after 1658. Rather the nineteenth and twentieth century changes of Church structure and services weakened or dispersed of the Danish traces. But then they were not any more interpreted as Danish. The ongoing, frequent amalgamation of parishes means a final break with the original, Danish Church structure in the co

The ALICE TPC provides excellent charged particle tracking to study pp and Pb-Pb collisions at LHC. The TPC allows also particle identification (PID) via the measurement of the specific ionisation dE/dx. At high p(T) (p(T) > 3 GeV/c) this is accomplished in the region of the relativistic rise of the energy loss, and provides a measurement of the yields of charged pions, kaons; and protons. Here, w

Calcitonin gene-related peptide (CGRP) has a key role in the pathophysiology of migraine and is associated with activation of the trigeminovascular system. Recently, CGRP receptor antagonists have been developed with clinical efficacy. The present thesis aimed therefore to investigate the distribution of CGRP and the CGRP receptor in the trigeminovascular system and in parts of the CNS. In the tri

One of multiple functions of metalloproteins is to provide detoxification to excess metal levels in organisms. Here we address the induction and persistence of a range of low to high molecular weight copper- and zinc binding proteins in the collembolan species Tetrodontophora bielanensis exposed to copper- and zinc-enriched food, followed by a period of recovery from metal exposure, in absence and