Sökresultat

Several definitions of treatment-resistant depression (TRD) are used for clinical research, but no verified model for use in register data exists. We aimed to compare a novel model created for use in register data—the Karolinska Institutet Model (KIM)–to the clinical definitions regarding the proportion of patients identified with TRD, their characteristics and clinical outcomes. Read more athttps

https://www.lupop.lu.se/article/register-based-approach-identifying-treatment-resistant-depression-comparison-clinical-definitions - 2025-10-25

The Japan Renal Biopsy Registry (J-RBR), the first nation-wide registry of renal biopsies in Japan, was established in 2007, and expanded to include non-biopsy cases as the Japan Kidney Disease Registry (J-KDR) in 2009. The J-RBR/J-KDR is one of the biggest registries for kidney diseases. It has revealed the prevalence and distribution of kidney diseases in Japan. This registry system was meant to

https://www.lupop.lu.se/article/revised-version-2018-nationwide-web-based-registry-system-kidney-diseases-japan-japan-renal-biopsy - 2025-10-25

Completeness was determined as the number of surgeries registered in DHAR in comparison with the number of surgeries registered in the Danish National Patient Registry database (DNPR). The number of patients self-reporting pre-surgical PROMs was compared to the total number of surgeries registered in DHAR. Read more athttps://www.dovepress.com/the-danish-hip-arthroscopy-registry-registration-compl

https://www.lupop.lu.se/article/danish-hip-arthroscopy-registry-registration-completeness-and-patient-characteristics-between - 2025-10-25

Data availability statements can provide useful information about how researchers actually share research data. We used unsupervised machine learning to analyze 124,000 data availability statements submitted by research authors to 176 Wiley journals between 2013 and 2019. We categorized the data availability statements, and looked at trends over time. We found expected increases in the number of d

https://www.lupop.lu.se/article/open-data-challenge-analysis-124000-data-availability-statements-and-ironic-lesson-about-data - 2025-10-25

Long-chain polyunsaturated fatty acids (LCPUFA) can be synthesised endogenously from linoleic acid (LA) and α-linolenic acid (ALA) in a pathway involving the fatty acid desaturase (FADS) genes. Endogenous synthesis is inefficient; therefore, dietary intake of preformed LCPUFA from their richest source of fish is preferred. This study investigated the effect of fish consumption on PUFA concentratio

https://www.lupop.lu.se/article/influence-fish-consumption-serum-n-3-polyunsaturated-fatty-acid-pufa-concentrations-women - 2025-10-25

Knowledge of predictive factors can foster the development of preventive approaches. This study examined how prevalence and severity of fall-related activity avoidance evolve over a 3-year period in people with Parkinson disease (PD). A specific aim was to identify predictive factors of fall-related activity avoidance (ie, modified Survey of Activities and Fear of Falling in the Elderly [mSAFFE] s

https://www.lupop.lu.se/article/predictive-factors-fall-related-activity-avoidance-people-parkinson-disease-longitudinal-study-3 - 2025-10-25

Patients with SLE diagnosed from 1981 to 2006 were followed through to 2016. IRRs of AMI and CVE were calculated. The AMI and CVE incidence patterns for patients with SLE were studied in relation to hypertension, smoking, renal dysfunction, anticardiolipin (aCL) antibodies at diagnosis, disease duration and organ damage before an event. Read more athttps://lupus.bmj.com/content/7/1/e000398

https://www.lupop.lu.se/article/disease-duration-age-diagnosis-and-organ-damage-are-important-factors-cardiovascular-disease-sle - 2025-10-25

Iodine has been suggested to protect against breast cancer, but there are no epidemiologic studies on individual risk. An interesting finding is that in areas where the exposure to both selenium and iodine are high (e.g., Japan), the risk of breast cancer is lower than in areas where selenium is high and iodine low (e.g., United States), or in areas where both are low (e.g., Northern Europe). The

https://www.lupop.lu.se/article/serum-iodine-and-breast-cancer-risk-prospective-nested-case-control-study-stratified-selenium-levels - 2025-10-25

In emergency department (ED) chest pain patients, it is believed that the diagnostic accuracy of the electrocardiogram (ECG) for acute coronary syndrome (ACS) is higher during ongoing than abated chest pain. Read more athttps://www.sciencedirect.com/science/article/pii/S0736467920301463?via…

https://www.lupop.lu.se/article/emergency-department-chest-pain-patients-or-without-ongoing-pain-characteristics-outcome-and - 2025-10-25

Over a 5-year period all pelvic radiographs from the Swedish surveillance programme for CP and the recorded data for scoliosis and hip abduction in children from southern Sweden at Gross Motor Function Classification System (GMFCS) levels II–V were analysed. PO and hip displacement calculated as migration percentage (MP) were measured on supine pelvic radiographs and compared with presence of scol

https://www.lupop.lu.se/article/association-between-pelvic-obliquity-and-scoliosis-hip-displacement-and-asymmetric-hip-abduction - 2025-10-25

The associations between sociodemographic factors and HbA1c variability in type 2 diabetes are not yet established. Examining group differences in HbA1c variability may help identify patient characteristics related to diabetes management. The present study examined differences in baseline HbA1c and HbA1c variability between groups with regard to sex, level of education, civil status, age, and BMI,

https://www.lupop.lu.se/article/sociodemographic-factors-associated-hba1c-variability-type-2-diabetes-prospective-exploratory-cohort - 2025-10-25

Much progress has been made in twin research since our last special issue on twin registries (Hur, Y.-M., & Craig, J. M. (2013). Twin Research and Human Genetics, 16, 1–12.). This special issue provides an update on the state of twin family registries around the world. This issue includes 61 papers on twin family registries from 25 countries, of which 3 describe consortia based on collaborations o

https://www.lupop.lu.se/article/twin-family-registries-worldwide-important-resource-scientific-research-0 - 2025-10-25

With the increasing move to publish manuscripts online, the science community needs to consider what effect this will have on their ability to communicate findings effectively to not only the science community but to the public as well. Online manuscripts are not a new concept. The increasing trend towards online use will be seamless for many. Yet, with information readily available at our fingert

https://www.lupop.lu.se/article/communicating-science-age-screen-reading-taking-page-journalism - 2025-10-25

The concurrent sampling design was developed for case–control studies of recurrent events. It involves matching for time. Standard conditional logistic-regression (CLR) analysis ignores the dependence among recurrent events. Existing methods for clustered observations for CLR do not fit the complex data structure arising from the concurrent sampling design. Read more at https://academic.oup.com/ij

https://www.lupop.lu.se/article/statistical-inference-matched-case-control-studies-recurrent-events - 2025-10-25

The Valencia Health System Integrated Database (VID) is a set of multiple, public, population-wide electronic databases for the Valencia Region, the fourth most populated Spanish region, with ∼5 million inhabitants and an annual birth cohort of 48 000 newborns, representing 10.7% of the Spanish population and around 1% of the European population. Read more at https://academic.oup.com/ije/article/4

https://www.lupop.lu.se/article/data-resource-profile-valencia-health-system-integrated-database-vid - 2025-10-25

The Philippine National Nutrition Survey (NNS) is the official nationwide survey on nutritional status, diet and other lifestyle-related risk factors for noncommunicable diseases. The NNS is designated to generate critical data for decision making by the government and the private sector in the Philippines. Data from the NNS have been used as a reference for formulating the Philippine Plan of Acti

https://www.lupop.lu.se/article/data-resource-profile-philippine-national-nutrition-survey-nns - 2025-10-25

The Maule Cohort (MAUCO) is the first prospective population-based cohort of cardiovascular disease (CVD) and cancer in central Chile. The rationale for this cohort is based on the social, environmental and health characteristics of an under-studied rural population at high risk for chronic diseases. Read more at https://academic.oup.com/ije/article/49/3/760/5807634

https://www.lupop.lu.se/article/cohort-profile-maule-cohort-mauco - 2025-10-25

Rapport om resultat från registerbaserad forskning på LU på forskning.se Ny forskning ledd från Karolinska Institutet ger ytterligare stöd för ett misstänkt samband mellan antibiotika av typen kinoloner och ökad risk för akut aortasjukdom. Med i studien är även Malin Inghammar från Lunds Universitet.

https://www.lupop.lu.se/article/antibiotika-kopplas-till-risk-akut-aortasjukdom - 2025-10-25

In many resource-constrained settings, availability of reliable vital statistics and health information is limited by lack of proper system for civil registration and health information. This is further limited by the fact that the majority of population health events, such as births, morbidity and mortality, occur outside the reach of these systems. In particular, obtaining credible data from rur

https://www.lupop.lu.se/article/cohort-profile-kalolenirabai-community-health-and-demographic-surveillance-system - 2025-10-25

The Finnish Gestational Diabetes (FinnGeDi) study is a multicentre study that considered Finnish women who gave birth in 2009–12, as well as their children and the children’s fathers. The study period was after the introduction of new Finnish national comprehensive screening guidelines for gestational diabetes mellitus (GDM). The study consisted of two arms: a prospective clinical, genetic case-co

https://www.lupop.lu.se/article/cohort-profile-finnish-gestational-diabetes-finngedi-study - 2025-10-25