Published 8 November 2021 In an extension of Mendelian randomization, we leveraged variation in genetic risk for late-onset AD risk to estimate the causal effect of AD on BMI and the earliest ages at which AD-related weight loss (or lower BMI as a proxy) occurs. Read the paper at https://academic.oup.com/aje/article/190/10/2163/6222073

https://www.lupop.lu.se/article/extension-mendelian-randomization-identify-earliest-manifestations-alzheimer-disease - 2025-01-25

Published 9 November 2021 Adjusting for epidemic curves based on surveillance data is necessary if estimates of missed cases and the effective reproduction number play a role in management of the COVID-19 pandemic. Read the paper at https://journals.lww.com/epidem/Fulltext/2021/11000/Effect_of_Adjustmen…

https://www.lupop.lu.se/article/effect-adjustment-case-misclassification-and-infection-date-uncertainty-estimates-covid-19-effective - 2025-01-25

Published 10 November 2021 We developed and validated a synthetic cohort approach to examine numbers of cardiovascular risk factors (CRFs) and adverse clinical events, including incident cardiovascular disease and all-cause mortality, across the life span from ages 20 years to 90 years. Read the paper at https://academic.oup.com/aje/article/190/10/2208/6274861

https://www.lupop.lu.se/article/development-and-validation-large-synthetic-cohort-study-cardiovascular-health-across-life-span - 2025-01-25

Published 11 November 2021 Smart card data (SCD) allow analyzing mobility at a fine level of detail, despite the remaining challenges such as identifying trip purpose. The use of the SCD may improve the understanding of transit users' travel patterns from precarious settlements areas, where the residents have historically limited access to opportunities and are usually underrepresented in surveys.

https://www.lupop.lu.se/article/big-data-big-issues-revealing-travel-patterns-low-income-population-based-smart-card-data-mining - 2025-01-25

Published 12 November 2021 Nationwide healthcare registries are potential important real-world data (RWD) sources for assessing drug effectiveness in oncology. However, it is unclear whether registry-derived RWD are suitable for clinical development. Read the paper at https://ascpt.onlinelibrary.wiley.com/doi/10.1002/cpt.2424

https://www.lupop.lu.se/article/replication-oncology-randomized-trial-results-using-swedish-registry-real-world-data-feasibility - 2025-01-25

Published 13 November 2021 Despite progress toward curtailing opioid prescribing, physicians are often slow to adopt new prescribing practices. Using the Abdominal Core Health Quality Collaborative (ACHQC), we aimed to demonstrate the ability of a national, disease-specific, personalized registry to impact opioid prescribing. Read the paper at https://link.springer.com/content/pdf/10.1007/s10029-0

https://www.lupop.lu.se/article/utilization-national-registry-influence-opioid-prescribing-behavior-after-hernia-repair - 2025-01-25

Published 14 November 2021 The overall accuracy of data held in the New Zealand Trauma Registry (NZTR) is suitable for quality improvement and benchmarking purposes, but more work is needed to improve the accuracy of individual cases, particularly those with head/neck and chest injury. Read the paper at https://journals.sagepub.com/doi/full/10.1177/14604086211041877

https://www.lupop.lu.se/article/accuracy-injury-coding-trauma-registry - 2025-01-25

Published 15 November 2021 A well-managed institutional arthroplasty registry, including structured clinical and radiological follow-up assessments, offers the opportunity for high-quality long-term patient and arthroplasty outcome analysis. Such data are not only helpful for analyzing patient outcome and implant survival, but will be increasingly important to justify our daily clinical practice a

https://www.lupop.lu.se/article/establishing-institutional-reverse-total-shoulder-arthroplasty-registry - 2025-01-25

Published 16 November 2021 We developed standardized QA processes for training, certification and supervision of the MNHR, a multisite research registry. It is expected that these activities, together with ongoing QA processes, will help to further optimize data quality for this protocol. Read the paper at https://reproductive-health-journal.biomedcentral.com/articles/10.1186/…

https://www.lupop.lu.se/article/looking-beyond-numbers-quality-assurance-procedures-global-network-womens-and-childrens-health - 2025-01-25

Published 17 November 2021 This registry will assess outcomes in patients with genetically confirmed SMA and provide information on the effectiveness and long-term safety of approved and emerging treatments. Read the paper at https://content.iospress.com/articles/journal-of-neuromuscular-diseases…

https://www.lupop.lu.se/article/restore-prospective-multinational-registry-patients-genetically-confirmed-spinal-muscular-atrophy - 2025-01-25

Published 18 November 2021 Our findings suggest that in studies of air pollution and cardiometabolic disease, which use an adjustment strategy with a broad range of register-based socioeconomic variables, there is no effect on risk estimates from subsequent lifestyle adjustment. Read the paper at https://www.sciencedirect.com/science/article/pii/S0013935121011816

https://www.lupop.lu.se/article/effect-adjustment-register-based-and-questionnaire-based-covariates-association-between-air - 2025-01-25

Published 19 November 2021 The registration committee for esophageal cancer in the Japan Esophageal Society (JES) has collected the patients' characteristics, treatment, and outcomes annually. Read the paper at https://link.springer.com/article/10.1007%2Fs10388-021-00879-1

https://www.lupop.lu.se/article/comprehensive-registry-esophageal-cancer-japan-2014 - 2025-01-25

Published 20 November 2021 Stroke is the second most common cause of adult death in Africa. This study reports the demographics, stroke types, stroke care and hospital outcomes for stroke in Freetown, Sierra Leone. Read the paper at https://www.frontiersin.org/articles/10.3389/fneur.2021.712060/full

https://www.lupop.lu.se/article/prospective-stroke-register-sierra-leone-demographics-stroke-type-stroke-care-and-hospital-outcomes - 2025-01-25

Published 21 November 2021 Among THR patients value sets based on the same method and perspective, a direct transfer of results across countries could be meaningful. In cases of differences in methods and perspectives among value sets, transfer of value sets across settings would have to consider conversion through crosswalk. Read the paper at https://www.mdpi.com/2077-0383/10/18/4205

https://www.lupop.lu.se/article/concordance-among-swedish-german-danish-and-uk-eq-5d-3l-value-sets-analyses-patient-reported - 2025-01-25

Published 22 November 2021 Assortativity is the tendency of individuals connected in a network to share traits and behaviors. Through simulations, we demonstrated the potential for bias resulting from assortativity by vaccination, where vaccinated individuals are more likely to be connected with other vaccinated individuals. Read the paper at https://academic.oup.com/aje/article/190/11/2442/629235

https://www.lupop.lu.se/article/assortativity-and-bias-epidemiologic-studies-contagious-outcomes-simulated-example-context - 2025-01-25

Published 23 November 2021 Here, we outline 3 federal, publicly available data sources for estimating the number of people experiencing homelessness in the United States. We describe the appropriate uses and limitations of each data source in the context of infectious disease epidemiology. Read the paper at https://academic.oup.com/aje/article/190/11/2432/6159692

https://www.lupop.lu.se/article/data-sources-enumerate-people-experiencing-homelessness-united-states-opportunities-and-challenges - 2025-01-25

Published 24 November 2021 This review provides important insights about the benefits and challenges of using routinely-collected, population-based linked databases for conducting population-based multigenerational health research, and identifies opportunities for future research within and across the data-intensive environments at these six sites. Read the paper at https://www.ncbi.nlm.nih.gov/pm

https://www.lupop.lu.se/article/multigenerational-health-research-using-population-based-linked-databases-international-review - 2025-01-25

Published 16 November 2021 The senior lecturer in epidemiology with a focus on research must, in addition to conducting high-quality epidemiological research primarily concerning the etiology of allergic diseases and hypersensitivity, also have a leading role in environmental health risk assessment and teach epidemiology. Read more, and apply, at https://ki.varbi.com/en/what:job/jobID:371203/

https://www.lupop.lu.se/article/job-opportunity-senior-lecturer-epidemiology-focus-environmental-health-risk-assessment-ki - 2025-01-25

Published 18 November 2021 Läs mer på https://www.vr.se/aktuellt/nyheter/nyhetsarkiv/2021-11-17-datum-klara-f…

https://www.lupop.lu.se/article/datum-klara-vetenskapsradets-utlysningar-2022 - 2025-01-25

Published 24 November 2021 The research group of Epidemiology and Population Studies (EPI@Lund), lead by professor Jonas Björk, is looking for an associate researcher in Epidemiology, Public Health, Data Science or a closely related subject, to the project "Improved preparedness for future pandemic outbreaks using large-scale population data in epidemiological surveillance". The position is linked

https://www.lupop.lu.se/article/job-opportunity-associate-researcher-epidemiological-surveillance-studies - 2025-01-25