By marie [dot] jonsson [at] med [dot] lu [dot] se (Marie Jönsson and Alessandro Fiorenzano) - published 17 December 2021 A human midbrain organoid visualised by staining for proteins important during the maturation of dopaminergic neurons. (photo: Alessandro Fiorenzano) In their latest study, published in Nature Communications, the Parmar Lab has established midbrain organoids using silk microfibe

https://www.stemcellcenter.lu.se/article/human-midbrain-organoids-grown-silk-recapitulate-midbrain-development-and-support-functionally - 2025-03-03

By marie [dot] jonsson [at] med [dot] lu [dot] se (Marie Jönsson and Leal Oburoglu) - published 13 January 2022 An optimised iPSC-differentiation protocol allowed the authors to study endothelial cells (purple), transitioning cells (pink), and hematopoietic stem-like cells (blue) using scRNA-seq. A UMAP visualise the cells in the shape of a butterfly. In a recent study from the SCC group of Niels-

https://www.stemcellcenter.lu.se/article/metabolic-switch-during-embryonic-hematopoiesis-major-regulator-lineage-commitment - 2025-03-03

By marie [dot] jonsson [at] med [dot] lu [dot] se (Magdalena Madej and Marie Jönsson) - published 20 January 2022 Ludwig Schmiderer has studied how to overcome delivery challenges in stem cell biology with nanotechnology. In this interview, he tells us about his research and generative art. What have you been working with during your PhD studies? At the beginning of my PhD, I was trying to reengin

https://www.stemcellcenter.lu.se/article/phd-defence-interview-ludwig-schmiderer - 2025-03-03

By marie [dot] jonsson [at] med [dot] lu [dot] se (Marie Jönsson and Björn Nilsson) - published 27 January 2022 The Nilsson lab performed a genome-wide association study on 13,167 individuals, 18-78 years old, and identified previously unknown regulators of blood HSPC levels. Stem cell transplantation is a cornerstone in the treatment of blood malignancies. In order to succeed, stem cells need to

https://www.stemcellcenter.lu.se/article/large-scale-genome-wide-association-study-reveals-new-potential-drug-target-blood-stem-cell - 2025-03-03

By asa [dot] hansdotter [at] med [dot] lu [dot] se (Faculty of Medicine) - published 14 March 2022 Principal Investigator, Filipe Pereira. Photo: Kennet Ruona The Pereira research group has previously shown that it is possible to reprogram human skin cells into dendritic cells that strengthen the immune system. However, the efficiency of these reprogrammed cells has been shown to be very low. New

https://www.stemcellcenter.lu.se/article/new-findings-indicate-ways-increase-efficiency-reprogrammed-immune-cells - 2025-03-03

By asa [dot] hansdotter [at] med [dot] lu [dot] se (Åsa Hansdotter) - published 15 March 2022 Charlotta Böiers, head of StemTherapy FACS Core Facility research infrastructure, and Mikael Sommarin, research engineer, discuss the results of a 22-colour analysis made on the new FACS device Symphony S6. Photo: Åsa Hansdotter. Anna Fossum, Project Manager at the StemTherapy FACS Core Facility research

https://www.stemcellcenter.lu.se/article/new-addition-lund-stem-cell-center-facs-facility - 2025-03-03

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 29 March 2022 Photo of Dr. Cristian Bellodi and Dr. Sowndarya Muthukumar Researchers from Lund University, building on previous studies, have been working to understand why stem cells are transforming into cancer. Previously they revealed that small RNA molecules, long considered “junk” or degradation byproducts of RNA

https://www.stemcellcenter.lu.se/article/what-makes-stem-cells-transform-cancer-answer-may-lie-our-rna - 2025-03-03

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 11 April 2022 Photo of Svetlana Soboleva (right) and an image of her PhD thesis cover (left). Svetlana Soboleva is set to defend her Ph.D. thesis on 13 April, 2022. For the past few years her world has revolved around red blood cells, as she has worked to establish methods that allow for the generation of enucleated ce

https://www.stemcellcenter.lu.se/article/blood-lab-phd-defence-interview-svetlana-soboleva - 2025-03-03

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 13 April 2022 One of the Electrophysiology Core Facilities' rigs in use during an experiment. Photo credit: Johan Persson. This year Lund Stem Cell Center and MultiPark, two strategic research areas based at Lund University, are happy to launch a new joint technical platform in an effort to ensure easy access to high q

https://www.stemcellcenter.lu.se/article/lund-scc-and-multipark-join-forces-ensure-researchers-have-high-quality-electrophysiology-facilities - 2025-03-03

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 19 April 2022 The MSCA Logo (left) and a photo of Camila Vazquez Echegaray (right). The Marie Skłodowska-Curie Actions (MSCA) fund excellent research and innovation. This March, the MSCA awarded €242m to the 2021 Postdoctoral Fellowships applicants – among them, a researcher from Lund University, Camila Vazquez Echegar

https://www.stemcellcenter.lu.se/article/msca-postdoctoral-fellowship-awarded-camila-vazquez-echegaray - 2025-03-03

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 27 April 2022 Cancerfonden distributed SEK 37 million to 8 researchers at Lund University in 2022. Included in this group is, Dr. Sowndarya Muthukumar (left). Cancerfonden continues to fund the foremost cancer research in Sweden – investing in cancer research that makes a difference. Last month, Cancerfonden distribute

https://www.stemcellcenter.lu.se/article/cancerfonden-awards-sowndarya-muthukumar-postdoctoral-fellowship - 2025-03-03

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 21 April 2022 Cancer is a genetic disease, caused by a change in the genes which make up our DNA. Normally one change or mutation is not enough to trigger the development of cancer, instead cancer is typically comprised of a combination of genetic mutations. Researchers at Lund University have now revealed a novel soma

https://www.stemcellcenter.lu.se/article/new-findings-reveal-what-may-be-triggering-disease-progression-acute-myeloid-leukemia - 2025-03-03

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 2 May 2022 Fluorescent microscope image of control MBP-positive oligodendrocytes (in green) co-stained with alpha-synuclein (in red). It is possible to observe neurites positive for alpha-synuclein. Photo Credit: Carla Azevedo. Researchers from Lund University, led by Dr. Laurent Roybon, are working to further define u

https://www.stemcellcenter.lu.se/article/new-findings-may-lead-way-future-therapeutic-approaches-parkinsons-disease-and-similar-diseases - 2025-03-03

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 4 May 2022 A laboratory expert in action in the Cell and Gene Therapy Core Facility. Lund Stem Cell Center provides researchers with access to core facilities equipped with the latest technologies, specialist expertise and instruction on the use of the different equipment. Over time these facilities have evolved to for

https://www.stemcellcenter.lu.se/article/new-cell-and-gene-therapy-core-facility-opening-its-doors-scientific-business - 2025-03-03

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 6 May 2022 Photo of the BMC building (left) and a portrait of Sandeep Gopal (right). We are happy to announce that Sandeep Gopal, a researcher within the Department of Experimental Medical Sciences at Lund University, has now joined Lund Stem Cell Center. In his new role as Principal Investigator and leader of the rese

https://www.stemcellcenter.lu.se/article/lund-stem-cell-center-welcomes-new-member-sandeep-gopal - 2025-03-03

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 11 May 2022 The members of the Stem Cell and Leukaemia Research Group. Researchers at Lund University have recently sought to shed more light on how normal hematopoietic stem cells (HSCs) produce a vast variety of blood cells. Their latest findings, now out in Cell Reports this week, confirm the existence of a transiti

https://www.stemcellcenter.lu.se/article/shedding-new-light-intermediate-cell-states-stem-cells-decide-their-fate - 2025-03-03

By asa [dot] hansdotter [at] med [dot] lu [dot] se (Åsa Hansdotter) - published 7 June 2022 Paul Bourgine, researcher and Wallenberg Fellow in Molecular Medicine, has been awarded an ERC Proof of Concept, consisting of EUR 150,000. Photo: Kennet Ruona. By using cells isolated from cancer patients and mixing them with a new technology called “OssiGel”, it is possible to engineer human mini-bones. T

https://www.stemcellcenter.lu.se/article/miniature-bones-research-model-cancer - 2025-03-03

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 13 June 2022 Pipetting in the dark. Special care was taken to prevent the introduction of artificial oxidation into the group's laboratory samples. A study conducted by researchers at Lund University has found that protein oxidation forms an additional layer of regulation during the development of fetal blood stem cell

https://www.stemcellcenter.lu.se/article/protein-oxidation-added-layer-regulation-during-blood-stem-cell-development - 2025-03-03

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 21 June 2022 Anders Björklund in the Lund University doctorate ceremony procession. Photo Credit: Paulina Pettersson. Life is like a marathon. According to Dr. Anders Björklund, a pioneer and expert in cell replacement strategies for patients with Parkinson’s Disease, so is life in academia. Along his scientific run he

https://www.stemcellcenter.lu.se/article/looking-long-magnificent-road-neuroscientists-life-interview-anders-bjorklund - 2025-03-03

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 24 June 2022 A graphical image depicting the reprogramming of human skin cells to astrocytes. Image credit: Cathrine Ahlenius Researchers from Lund University interested in understanding how aging affects the brain have made a new discovery that will help make it easier to study age-related brain diseases and potential

https://www.stemcellcenter.lu.se/article/how-our-skin-cells-might-be-key-better-understanding-human-brain - 2025-03-03