Published 9 September 2020 While discontinuation of COPD maintenance medication is a known problem, the proportion of patients with discontinuation and its geographical and sociodemographic distribution are so far unknown in Sweden. Therefore, we analyse this question by applying an innovative approach called multilevel analysis of individual heterogeneity and discriminatory accuracy (MAIHDA). Rea

https://www.lupop.lu.se/article/geographical-and-sociodemographic-differences-discontinuation-medication-chronic-obstructive - 2025-03-09

Published 9 September 2020 During the last 4 decades, registration of patients with primary immunodeficiencies (PID) has played an essential role in different aspects of these diseases worldwide including epidemiological indexes, policymaking, quality controls of care/life, facilitation of genetic studies and clinical trials as well as improving our understanding about the natural history of the d

https://www.lupop.lu.se/article/global-systematic-review-primary-immunodeficiency-registries - 2025-03-09

Published 2 September 2020 Research Services is pleased to announce a pair of webinars on research funding from some of the biggest funders in Sweden. These webinars will give you a chance to hear straight from the funders about their schemes and funding philosophy, and they will also answer your questions directly. The webinars are open to all researchers at Lund, and no prior knowledge of the fu

https://www.lupop.lu.se/article/research-services-presents-meet-funders - 2025-03-09

Published 10 September 2020 Oesophagogastric cancers carry a high mortality, economic burden and rising incidence. There is a need to monitor and improve care for this disease. Pathologic information is a cornerstone of cancer diagnosis, treatment and prognosis. Few population-based studies combine pathology information and clinical outcomes. The objective of this study is to develop a clinical an

https://www.lupop.lu.se/article/population-registry-esophageal-and-stomach-tumours-ontario-presto-protocol-multicentre-clinical-and - 2025-03-09

Published 10 September 2020 Read more at https://moh-it.pure.elsevier.com/en/publications/the-italian-registry-for-primary-immunodeficiencies-italian-prima-2

https://www.lupop.lu.se/article/italian-registry-primary-immunodeficiencies-italian-primary-immunodeficiency-network-ipinet-twenty - 2025-03-09

Published 11 September 2020 Alpha-1 antitrypsin deficiency (AATD) is a rare and underdiagnosed disease that is associated with the development of liver disease in adults and children and pulmonary emphysema in adults. Several studies have shown that there is limited knowledge about the disease and its diagnosis among health care providers, and there is an important inequity in the access to specia

https://www.lupop.lu.se/article/importance-reference-centers-and-registries-rare-diseases-example-alpha-1-antitrypsin-deficiency - 2025-03-09

Published 11 September 2020 This study exploits policy reforms in Swedish primary care to examine the effect of pay-for-performance (P4P) on compliance with hypertension drug guidelines among public and private health care providers. Using provider-level outcome data for 2005–2013 from the Swedish Prescription Register, providers in regions using P4P were compared to providers in other regions in

https://www.lupop.lu.se/article/effects-pay-performance-prescription-hypertension-drugs-among-public-and-private-primary-care - 2025-03-09

Published 12 September 2020 Congenitally corrected and surgical atrial redirected transposition of the great arteries (TGA) represents states where the morphological right ventricle serves as a systemic ventricle (S-RV). The S-RV is prone to failure, but data on medical treatment on this problem is limited. The purpose of this study was to evaluate the survival in adults with S-RV, with or without

https://www.lupop.lu.se/article/effect-medical-treatment-patients-systemic-right-ventricle - 2025-03-09

Published 12 September 2020 Diabetes mellitus (DM) and colorectal cancer (CRC) share some risk factors, including lifestyle and metabolic disturbances. We aimed to provide in-depth information on the association of CRC risk, especially early-onset CRC, with DM, family history of CRC, and age at DM diagnosis. Read more at https://journals.lww.com/ajg/Fulltext/2020/07000/Personal_History_of_Diabetes

https://www.lupop.lu.se/article/personal-history-diabetes-important-family-history-colorectal-cancer-risk-colorectal-cancer - 2025-03-09

Published 13 September 2020 People with Parkinson’s disease (PD) have lower life satisfaction (LS) than healthy peers. No study has yet identified predictors of LS in people with PD. Such information would be valuable for health care and future interventions that aim to maintain or increase LS. Read more at https://www.hindawi.com/journals/pd/2020/1561037/

https://www.lupop.lu.se/article/prediction-life-satisfaction-people-parkinsons-disease - 2025-03-09

Published 9 March 2018 Eight new calls for proposal are now open The Swedish Research Council has now opened several calls for proposals within Natural and engineering sciences, Educational sciences and Development research. Most of the calls are open until 10 April, but the Network grant within Educational Sciences is open until 27 March.Read more at www.vr.se.

https://www.lupop.lu.se/article/new-calls-proposal-vr - 2025-03-09

Published 13 September 2020 Red blood cell (RBC) transfusions are associated with risks including immunological reactions and volume overload. Current guidelines suggest a restrictive transfusion strategy in most patients with sepsis but based on previous randomized controlled trials and observational studies, there are still uncertainties about the safety in giving low-grade RBC transfusions to p

https://www.lupop.lu.se/article/mortality-and-morbidity-low-grade-red-blood-cell-transfusions-septic-patients-propensity-score - 2025-03-09

Published 14 September 2020 Data from the Swedish National Registry for Pancreatic and Periampullary Cancer for all patients undergoing a PD from 2010 until 30th June 2018 were collected. The material was analysed in two groups, no POPF and clinically relevant (grade B and C) POPF. Read more at https://link.springer.com/article/10.1007/s00268-020-05735-4

https://www.lupop.lu.se/article/predictive-factors-postoperative-pancreatic-fistula-swedish-nationwide-register-based-study - 2025-03-09

Published 14 September 2020 Cold sensitivity is common following nerve injuries in the upper extremity, but is less well studied in carpal tunnel syndrome (CTS). We investigated cold sensitivity in CTS and its effects on surgical outcome. A search of the Swedish National Registry for Hand Surgery (HAKIR) for open carpal tunnel releases (OCTR) from 2010–2016 identified 10,746 cases. Symptom severit

https://www.lupop.lu.se/article/occurrence-cold-sensitivity-carpal-tunnel-syndrome-and-its-effects-surgical-outcome-following-open - 2025-03-09

Published 15 September 2020 Two hundred and eighty‐one patients hospitalized for HF (mean age, 74 years; 32% women) were assessed using cognitive tests: Montreal Cognitive Assessment (MoCA), A Quick Test of Cognitive speed, Trail Making Test A, and Symbol Digit Modalities Test. The mean follow‐up time censored at rehospitalization or death was 13 months (interquartile range, 14) and 28 months (int

https://www.lupop.lu.se/article/cognitive-test-results-are-associated-mortality-and-rehospitalization-heart-failure-swedish - 2025-03-09

Published 15 September 2020 Investigations of social-genetic effects, whereby a social partner’s genotype affects another’s outcomes, can be confounded by the influence of the social partner’s rearing environment. We used marital information on more than 300,000 couples from Swedish national data to disentangle social-genetic from rearing-environment effects for alcohol use disorder (AUD). Read mo

https://www.lupop.lu.se/article/disentangling-social-genetic-rearing-environment-effects-alcohol-use-disorder-using-swedish-national - 2025-03-09

Published 16 September 2020 Adult-onset growth hormone deficiency (AGHD) is usually the last deficiency to be substituted in hypopituitarism. In children with documented GH deficiency, treatment without delay is crucial for achieving optimal effects on growth and development. In adults, it is not known whether a delay in treatment initiation influences biochemical response and the favourable physi

https://www.lupop.lu.se/article/early-versus-late-initiation-gh-replacement-adult-onset-hypopituitarism - 2025-03-09

Published 16 September 2020 Rates of knee replacement (KR) are increasing worldwide. Based on population and practice changes, there are forecasts of a further exponential increase in primary knee replacement through to 2030, and a corresponding increase in revision knee replacement. We used registry data to document changes in KR over the past 15 years, comparing practice changes across Sweden, A

https://www.lupop.lu.se/article/increases-rates-primary-and-revision-knee-replacement-are-reducing-15-year-registry-study-across-3 - 2025-03-09

Published 10 March 2018 In the annual open call Formas welcomes applications within its three areas of responsibility - Environment, Agricultural Sciences and Spatial Planning. The purpose of the call is to enable researchers to address self-identified research needs and is divided into three sub-calls:Research and development projectsResearch and development projects for future research leadersMo

https://www.lupop.lu.se/article/formas-annual-open-call-2018-now-open - 2025-03-09

Published 17 September 2020 Influenza may precipitate cardiovascular disease, but influenza typically peaks in winter, coinciding with other triggers of myocardial infarction (MI) such as low air temperature, high wind velocity, low atmospheric pressure, and short sunshine duration. Read more at https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0236866

https://www.lupop.lu.se/article/association-acute-myocardial-infarction-influenza-nationwide-observational-study - 2025-03-09