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Tyr-716 in the platelet-derived growth factor beta-receptor kinase insert is involved in GRB2 binding and Ras activation

Ligand stimulation of the platelet-derived growth factor (PDGF) beta-receptor leads to activation of its intrinsic tyrosine kinase and autophosphorylation of the intracellular part of the receptor. The autophosphorylated tyrosine residues mediate interactions with downstream signal transduction molecules and thereby initiate different signalling pathways. A pathway leading to activation of the GTP

Test-grounds of Modernity: A Swedish Landscape in Transformation during the early 20th century

The aim of this paper is to demonstrate some examples of how landscape changes in a rural setting in Sweden during the 19th and early 20th century could be understood as processes of modernity, and how the landscape could be understood as a medium for these changes. One purpose is to to come to a closer understanding of landscape changes during a period that is not so much studied within Swedish h

A self-tuning predictor

An adaptive predictor for discrete time stochastic processes with constant but unknown parameters is described. The predictor which in real time tunes its parameters using the method of least squares is called a self-tuning predictor. The predictor has attractive asymptotic properties. If the parameter estimation converges and if the predictor contains parameters enough, then it will converge to t

Numerical modeling of Swirling Flows in Gas Turbine Burners

The present thesis focuses on the numerical simulation of the flowfield in gas turbine burners. Due to the higher and higher requirements regarding pollutant emissions there is a need for new combustion technologies. In gas turbines one method to obtain low pollutant levels is the use of lean premixed or partially premixed combustion. However, in lean combustion problems regarding the flame stabi