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Cross-talk between neural stem cells and immune cells: the key to better brain repair?

Systemic or intracerebral delivery of neural stem and progenitor cells (NSPCs) and activation of endogenous NSPCs hold much promise as potential treatments for diseases in the human CNS. Recent studies have shed new light on the interaction between the NSPCs and cells belonging to the innate and adaptive arms of the immune system. According to these studies, the immune cells can be both beneficial

A General Power-Series Expansion Method for Exact Analysis of the Guided Modes in an Optical Fiber

A power-series expansion method for rigorous analysis of the guided modes in a cylindrical, radially inhomogeneous, dielectric waveguide is presented. The method is developed for an arbitrary piece-wise polynomial permittivity profile. The field solutions of the inhomogeneous core are constructed by a sequence of power-series expansions. Convergence is ensured and accuracy maintained by regulating

The game of Inquiry : the interrogative approach to inquiry and belief revision theory

I. Levi has advocated a decision-theoretic account of belief revision. We argue that the game-theoretic framework of Interrogative Inquiry Games, proposed by J. Hintikka, can extend and clarify this account. We show that some strategic use of the game rules (or ‘policies’) generate Expansions, Contractions and Revisions, and we give representation results. We then extend the framework to represent

I, COLEOPTILE (Book Review)

Review of the art and poetry collection "I, Coleoptile" by Austrian artist Kerstin Cmelka, and American-Austrian poet Ann Cotten.

Seroreactivity to Cutaneous Human Papillomaviruses among Patients with Nonmelanoma Skin Cancer or Benign Skin Lesions.

Cutaneous human papillomaviruses (HPV) are common in nonmelanoma skin cancers, benign skin lesions, and healthy skin. Increased seroprevalences for cutaneous HPV among nonmelanoma skin cancer patients have been described. To determine whether antibodies to cutaneous HPV are related to presence of the virus and/or to skin disease, we collected serum and biopsies from both lesions and healthy skin f

Genetic variance in the adiponutrin gene family and childhood obesity.

AIM: The adiponutrin gene family consists of five genes (PNPLA1-5) coding for proteins with both lipolytic and lipogenic properties. PNPLA3 has previously been associated with adult obesity. Here we investigated the possible association between genetic variants in these genes and childhood and adolescent obesity. METHODS/RESULTS: Polymorphisms in the five genes of the adiponutrin gene family were