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Targeted Prostate Cancer Screening in BRCA1 and BRCA2 Mutation Carriers: Results from the Initial Screening Round of the IMPACT Study.

Men with germline breast cancer 1, early onset (BRCA1) or breast cancer 2, early onset (BRCA2) gene mutations have a higher risk of developing prostate cancer (PCa) than noncarriers. IMPACT (Identification of Men with a genetic predisposition to ProstAte Cancer: Targeted screening in BRCA1/2 mutation carriers and controls) is an international consortium of 62 centres in 20 countries evaluating the

Estimation of patient doses from X-ray examinations in the Bryansk region hospitals

During 2012 - 2013 a study to evaluate conventional X-ray procedures and patient doses in Klintzi and Novozibkov areas of Bryansk region, Russia, was conducted. X-ray operation parameters included quality assurance of equipment, collection of procedure parameters and clinical practice evaluation. Effective doses were calculated for each selected procedure and dose distributions were established. 7

Some Aspects of Mobile Map Services

The technology of today, with the use of computers and the Internet, has enabled new types of map usage. Screen maps provide possibilities that could never be offered by standard paper maps, and allow maps to be integrated into information services. Mobile map services are information services adapted to mobility; using small screen presentation devices and communication networks to access various

Patient-reported 28 swollen and tender joint counts accurately represent RA disease activity and can be used to assess therapy responses at the group level.

Objective. Formal joint assessments are critically important to improve rheumatological care of patients with RA. The aim of this study was to determine the usefulness of patient-recorded 28 tender joint counts (TJCs) and swollen joint counts (SJCs) using a tablet personal computer and to explore the possibility of using patient-recorded data to calculate 28-joint DAS (DAS-28) and EULAR response.

Molecular mechanisms of resistance to Rituximab and pharmacologic strategies for its circumvention.

The introduction of Rituximab has greatly improved therapeutic options for patients with B-cell non-Hodgkin lymphoma (B-NHL). However, a substantial fraction of patients with aggressive B-NHL fails first-line therapy, and most patients with relapsing indolent B-NHL eventually acquire Rituximab resistance. Molecular understanding of the underlying mechanisms facilitates the development of pharmacol

Rätten och den sociosymboliska sömnen - reflektioner om det industriella folkmordets eftereffekter

Combining cultural theory with the philosophy of law, this essay argues that the advent of state-managed, industrial genocide has brought about a crisis of confidence in the institutions of modern society. A wave of incrimination emanates from the holocaust, which primarily strikes against the institutions of law, but also affects the credibility of sociosymbolic mandate as such. Drawing on the wr

The metabolic syndrome and risk of myocardial infarction in familial hypertension (Hypertension Heredity in Malmö Evaluation study).

OBJECTIVES: The aim of this study was to examine whether three main definitions of the metabolic syndrome (MetS) - WHO, National Cholesterol Education Program-Adult Treatment Panel III and International Diabetes Federation - identify the same individuals and are able to predict incident myocardial infarction (MI) in families with essential hypertension. METHODS: The tested definitions were prospec