Sökresultat

Filtyp

Din sökning på "*" gav 529849 sökträffar

Quantitative Methods for Train Delay Propagation Research

Due to the increase in railway traffic, trains increasingly need to adhere to their scheduled path to avoid extensive propagation ofdelays. This paper presents the findings of a systematic literature review covering articles related to the delay propagation problemsof trains. By searching both the Scopus and Web of Science databases, the content of 156 relevant papers was screened andanalyzed. The

Real-time High-Speed Train Delay Prediction using Seemingly Unrelated Regression Models

Understanding the impact of various factors on train arrival delays is a prerequisite for effective railway traffic operating control andmanagement. Existing studies model the train delay prediction problems using a single, generic equation, restricting their capabilityin accounting for heterogeneous impacts of spatiotemporal factors on arrival delays as the train travels along its route. The pape

Evaluation Framework for Train Delays Prediction Models

Real-time train delay prediction is critical for ensur-ing the safety of train operations and providing quality serviceto passengers. The increasing demand for railway transportationhas led to the need for punctuality and the availability of advancetrain arrival time information to ensure a satisfactory travelexperience. Data-driven train prediction models have undergonesignificant advancements, a

ERS International Congress 2022 : highlights from the Basic and Translational Science Assembly

In this review, the Basic and Translational Science Assembly of the European Respiratory Society provides an overview of the 2022 International Congress highlights. We discuss the consequences of respiratory events from birth until old age regarding climate change related alterations in air quality due to pollution caused by increased ozone, pollen, wildfires and fuel combustion as well as the inc

Lung tissue bioengineering for transplantation and modelling of development, disease and regeneration

The lung is a vital and dynamic organ that serves as a critical first barrier to environmental stimuli and facilitates gas exchange from birth until death. Developmental or genetic defects that impair lung function severely impact quality of life. Minor defects present in early life increase the likelihood that patients will develop chronic lung diseases in adulthood that have no cure. Current the

Two-level eddy covariance measurements reduce bias in land-atmosphere exchange estimates over a heterogeneous boreal forest landscape

Estimates of land-atmosphere exchanges of carbon, energy, water vapor, and other greenhouse gases based on the eddy covariance (EC) technique rely on the fundamental assumption that the flux footprint area is homogeneous. We investigated the impact of source area heterogeneity on flux estimates in single-level EC measurements over a managed boreal forest landscape. For this purpose, we compared si

A neurophenomenological fMRI study of a spontaneous automatic writer and a hypnotic cohort

Purpose: To evaluate the neurophenomenology of automatic writing (AW) in a spontaneous automatic writer (NN) and four high hypnotizables (HH). Methods: During fMRI, NN and the HH were cued to perform sponta- neous (NN) or induced (HH) AW, and a comparison task of copying complex symbols, and to rate their expe- rience of control and agency. Results: Compared to copying, for all participants AW was

A Rapid and Tunable Approach for the Fractionation of Technical Kraft Lignin

Reducing the heterogeneity of technical lignin is essential to obtain predictable and high-performance polymeric materials that are suitable for high-value applications. Organic solvents with different polarities and solubilities can be used to fractionate lignin and reduce the complexity and diversity of its chemical structure. Among the various solvents and solvent mixtures, acetone-water mixtur

Oxidative Depolymerization of Kraft Lignin to Aromatics Over Bimetallic V–Cu/ZrO2 Catalysts

Zirconia-supported vanadium–copper catalysts (VCux:yZr) were used for the oxidative depolymerization of softwood LignoBoost Kraft lignin (LB). Various VCux:yZr catalysts were prepared (x:y = 0:1, 1:4, 1:2, 3:4, 1:1, and 1:0) by incipient wetness impregnation, and reactions were performed in alkaline water at 150 °C under an O2 pressure of 5 bar for 10 min. 1H–13C HSQC NMR spectroscopy was used for

Low levels of WRAP53 predict decreased efficacy of radiotherapy and are prognostic for local recurrence and death from breast cancer : a long-term follow-up of the SweBCG91RT randomized trial

Downregulation of the DNA repair protein WD40-encoding RNA antisense to p53 (WRAP53) has been associated with radiotherapy resistance and reduced cancer survival. The aim of this study was to evaluate WRAP53 protein and RNA levels as prognostic and predictive markers in the SweBCG91RT trial, in which breast cancer patients were randomized for postoperative radiotherapy. Using tissue microarray and

Can your darkness be measured? Analyzing the full and brief version of the Dark Factor of Personality in Swedish

The Dark Factor of Personality (D) measures the latent core of antagonistic traits. The present study evaluated the psychometric properties of the Swedish version of the full (D70) and the brief (D16) versions, concerning structural validity, item information, and convergent validity. An online sample (N = 294) was analyzed using CFA (Maximum Likelihood Estimation), IRT (Graded Response Model) and

Development, Validation, and Clinical Utility of a Six-gene Signature to Predict Aggressive Prostate Cancer

Background: Molecular signatures in prostate cancer (PCa) tissue can provide useful prognostic information to improve the understanding of a patient's risk of harbouring aggressive disease. Objective: To develop and validate a gene signature that adds independent prognostic information to clinical parameters for better treatment decisions and patient management. Design, setting, and participants:

GEDI : A New LiDAR Altimetry to Obtain the Water Levels of More Lakes on the Tibetan Plateau

Remote sensing is an effective means for lake water level monitoring on the Tibetan Plateau (TP). The purpose of this study is to estimate water levels of lakes on the TP using the Global Ecosystem Dynamics Investigation (GEDI) and Cloud and Land Elevation Satellite-2 (ICESat-2), evaluate the performance of ICESat-2 and GEDI in estimating water levels, and analyze the differences of water level ob

Latent heterogeneity of muscle-invasive bladder cancer in patient characteristics and survival : A population-based nation-wide study in the Bladder Cancer Data Base Sweden (BladderBaSe)

Background: Patients with muscle-invasive bladder cancer (MIBC) constitute a heterogenous group in terms of patient and tumour characteristics (‘case-mix’) and prognosis. The aim of the current study was to investigate whether differences in survival could be used to separate MIBC patients into separate classes using a recently developed latent class regression method for survival analysis with co

An exploratory modelling study of chemiluminescence in ammonia-fuelled flames. Part 1

The present exploratory study is aimed at the modelling of the chemiluminescence signature of premixed laminar NH3+H2+air flames. The detailed kinetic mechanism of the author was extended by reactions describing the formation and consumption of excited NO2*, NO(A), NH*, and NH2* mostly relying on previous analyses of chemiluminescence processes from the literature. The lowest-lying excited state o

Synovial monocytes contribute to chronic inflammation in childhood-onset arthritis via IL-6/STAT signalling and cell-cell interactions

INTRODUCTION: Monocytes are key effector cells in inflammatory processes. We and others have previously shown that synovial monocytes in childhood-onset arthritis are activated. However, very little is known about how they contribute to disease and attain their pathological features. Therefore, we set out to investigate the functional alterations of synovial monocytes in childhood-onset arthritis,