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C-Kit signal transduction and involvement in cancer

Receptor tyrosine kinases, such as c-Kit, are proteins whose function it is to transduce signals from the environment into the cell leading to complex behaviors such as proliferation, migration, survival and differentiation. Many of these behaviors are deregulated in cancer, which is characterized by uncontrolled proliferation, insensitivity towards death stimuli, migration of tumor cells away fro

On the Scalability of Visualization in Manufacturing

Computer graphics plays an important role in modern engineering of manufacturing systems, both during design using virtual engineering environments and also as part of user interfaces to various machines. Existing and emerging systems today make use of software components, usually providing a graphical view to the user. In manufacturing, 3D graphics is desirable to visualize geometries of equipmen

Den hälsovådliga resan i tiden

The text deals with the concept of time travelling into the past and how it is conceived. The author makes an evaluation of different approaches to the past that are either alternative or symbiotic or both in relation to both past and present time. Examples in the article relates to modern rune carvers and re-enactment traditions relating to the Iron age, the Viking Age and the Medieval period.

The role of connections as minimal norms in normative systems

The paper aims at developing an algebraic representation of normative systems by sets of minimal norms, "connections", within relational structures called condition implication structures. It is shown that, given some general presuppositions, a normative system is completely determined by its set of connections, and that comparisons between normative systems can be made by considering whether conn

Ferrochelatase and Magnesiumchelatase: Metal chelation studied with mutants

Popular Abstract in Swedish Tänk dig en solig sommardag. Du går runt med en glass i handen och mår allmänt bra. Runt om dig finns gröna lummiga träd och vackra blommor i alla möjliga färger. Naturen visar verkligen sin vackraste sida. I dagens samhälle tänker man inte så ofta på den mångfald av färger som omger oss. Den blåa himlen, den gula solen, det röda blodet och det gröna gräset. Kanske beroMagnesium chelatase and ferrochelatase are two very important enzymes, which are involved in chlorophyll and heme biosynthesis, respectively. They both use protoporphyrin IX as substrate but magnesium chelatase inserts a magnesium ion whereas ferrochelatase inserts a ferrous ion. These two enzymes have been studied in this thesis. Even though they both insert a metal ion into protoporphyrin IX the

Meaning Constitution Analysis: A Phenomenological Approach

Each and every thought, word, feeling or action of a person recele a surplus of meaning, opening on all the possible worlds accessible for him/her. A vision on those possible worlds and possibilities of action, should be of the highest interest for psychological research. Research in cross/cultural/intercultural psychology confronts the researcher to language, in conversations, narratives, writing