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Depersonalization disorder may be related to glutamate receptor activation imbalance.

Low-dose ketamine administration mimics, both clinically and on gross neuroimaging, depersonalization disorder. The perceptual effects of ketamine may be due to secondary stimulation of glutamate release and lamotrigine, possibly by inhibited glutamate release, may reduce some of ketamine's so-called dissociative effects. However, lamotrigine does not seem to be useful in the treatment of deperson

The rate of crossings of a quadratic form of an n-dimensional stationary Gaussian process

Consider a quadratic form of a vector valued differentiable stationary Gaussian process. The crossing intensity of a fixed level depends on the joint correlation structure of the process and its derivative, but no simple exact form is known for the general case. We give the first and second terms in an asymptotic expansion, which is valid as the level tends to infinity, and show how to find higher

Myeloid and lymphoid contribution to non-haematopoietic lineages through irradiation-induced heterotypic cell fusion.

Recent studies have suggested that regeneration of non-haematopoietic cell lineages can occur through heterotypic cell fusion with haematopoietic cells of the myeloid lineage. Here we show that lymphocytes also form heterotypic-fusion hybrids with cardiomyocytes, skeletal muscle, hepatocytes and Purkinje neurons. However, through lineage fate-mapping we demonstrate that such in vivo fusion of lymp

Clustering ECG complexes using Hermite functions and self-organizing maps

An integrated method for clustering of QRS complexes is presented which includes basis function representation and self-organizing neural networks (NN's). Each QRS complex is decomposed into Hermite basis functions and the resulting coefficients and width parameter are used to represent the complex. By means of this representation, unsupervised self-organizing NNs are employed to cluster the data

Vilken religion är sann och frågan om språkets obestämbarhet

There is nothing strange in asking what is true. There is nothing strange in asking whether what different religions proclaim is true, and if there is one of them that would be truer than others. Such questions surface when religions meet in various ways. How definite the answers can be depends on the level of linguistic stability, or so it is argued in this article. Therefore, understanding the f

Reading strategies and cognitive skills i children with cochlear implants

Abstract in UndeterminedThe present study investigated working memory capacity, lexical access, phonological skills and reading ability in 6 children with cochlear implants (CI), attending grades 1-3. For each test measure, the individual performance of the children was compared to a grade-matched comparison group of children with normal hearing. Performance was also studied in relation to demogra

Sperm chromatin structure assay in prediction of in vitro fertilization outcome.

Sperm DNA fragmentation index (DFI) assessed by sperm chromatin structure assay is a valuable tool for prediction of fertility in vivo. Previous studies on DFI as predictor of in vitro fertilization (IVF) outcome, based on relatively small materials, gave contradictory results. The present study examines, in a large cohort, the association between sperm DFI and the outcome of IVF/ICSI procedure. T

Airway responsiveness to mannitol in asthma is associated with chymase-positive mast cells and eosinophilic airway inflammation.

Airway hyperresponsiveness (AHR) to inhaled mannitol is associated with indirect markers of mast cell activation and eosinophilic airway inflammation. It is unknown how AHR to mannitol relates to mast cell phenotype, mast cell function and measures of eosinophilic inflammation in airway tissue. We compared the number and phenotype of mast cells, mRNA expression of mast cell associated genes and nu

Impact of relative humidity and water soluble constituents of PM2.5 on visibility impairment in Beijing, China

Beijing has been experiencing severe particulate pollution accompanying the fast growing population and economy. This study investigated the impact of PM2.5 and its water soluble organic and inorganic constituents on visual impairment in Beijing under different meteorological conditions. According to the analysis of PM2.5 samples collected in Spring 2012, water soluble species took up 38.1% of PM2

Evaluation of continuous and intermittent myocardial topical negative pressure.

OBJECTIVE: Topical negative pressure, commonly used in wound therapy, has been shown to increase blood flow and stimulate angiogenesis in subcutaneous tissue and skeletal muscle. In wound therapy, intermittent negative pressure is often preferred to continuous negative pressure as tissue exposed to intermittent therapy shows twice as much granulation tissue formation than that exposed to continuou

TWENTY YEARS OF HUMAN RESEARCH ETHICS COMMITTEES IN THE BALTIC STATES.

Two decades have passed since the first attempts were made to establish systematic ethical review of human research in the Baltic States. Legally and institutionally much has changed. In this paper we provide an historical and structural overview of ethical review of human research and identify some problems related to the role of ethical review in establishing quality research environment in thes

Barriers to adherence to hypertension guidelines among GPs in southern Sweden: A survey.

Objective. To evaluate barriers to adherence to hypertension guidelines among publicly employed general practitioners (GPs). Design. Questionnaire-based survey distributed to GPs in 24 randomly selected primary care centres in the Region of Skåne in southern Sweden. Subjects. A total of 109 GPs received a self-administered questionnaire and 90 of them responded. Main outcome measures. Use of risk

Nonintrusive gas monitoring in neonatal lungs using diode laser spectroscopy: feasibility study.

A feasibility study on noninvasive, real-time monitoring of gases in lungs of preterm infants is reported, where a laser-spectroscopic technique using diode lasers tuned to oxygen and water vapor absorption lines was employed on realistic tissue phantoms. Our work suggests that the technique could provide a new possibility for surveillance of the lung function of preterm infants, in particular the

Streptococcal M proteins and their role as virulence determinants.

Group A streptococci (GAS, Streptococcus pyogenes) are exclusive human pathogens that have been extensively studied for many decades. The spectrum of diseases caused by these bacteria ranges from uncomplicated and superficial to severe and invasive infections. In order to give rise to these complications, GAS have evolved a number of surface-bound and secreted virulence factors, of which the M pro

Prognostic value of proliferation in pleomorphic soft tissue sarcomas: a new look at an old measure.

Though proliferation has repeatedly shown a prognostic role in sarcomas, it has not reached clinical application. We performed a comprehensive evaluation of the prognostic role of 5 proliferation measures in a large series of soft tissue sarcomas of the extremities and the trunk wall. One hundred ninety-six primary soft tissue sarcomas of the extremities and the trunk wall were subjected to DNA fl