Postural orthostatic tachycardia syndrome (POTS) is a cardiovascular autonomic disorder with poorly understood etiology and underlying pathophysiology. Since cardiovascular morbidity has been linked to growth hormone (GH), we studied GH levels in patients with POTS. We conducted an age-sex-matched case-control study in patients with POTS (age 31 ± 9 years; n = 42) and healthy controls (32 ± 9 year

Hypertension and hypotension are strictly related phenomena, that frequently coexist within the spectrum of cardiovascular autonomic dysfunction, especially at advanced age. Indeed, antihypertensive treatment may predispose to orthostatic and post-prandial hypotension, while intensive blood pressure lowering may be responsible for systemic hypotension. Over recent years, systemic and orthostatic h

OBJECTIVE: Mortality caused by coronary artery disease has markedly decreased in recent years. However, a substantial proportion of patients suffering a coronary event (CE) die within the first day, most of them out of hospital. We aimed to investigate how established cardiovascular (CV) risk factors and CV autonomic indices associate with fatal versus non-fatal CEs in the population.METHODS: 33 0

Airway basal cells are crucial for regeneration of the human lung airway epithelium, and are thought to be important contributors to Chronic Obstructive Pulmonary Disease (COPD) and other lung disorders. In order to reveal how basal cells contribute to disease, and to discover novel therapeutic targets, these basal cells need to be further characterized. In this study, we optimized a flow cytometr

The Intermediate Data Structure (IDS) was developed as a strategy aimed at standardizing the dissemination of micro-level historical demographic data. The structure provides a common and clear data strategy which facilitates studies that consider several databases, and the development and exchange of software. Based on my own experiences from working with the IDS, in this article I provide reflect

Mounting evidence shows that early-life adversity negatively affects health in late life, but much less is known about if and how early-life conditions affect health in mid-life. In particular, knowledge is very limited regarding the connection between early-life adversity and reproductive health. This paper studies the effect of early-life disease exposure on women’s reproductive careers in mid-l

Background: It is currently estimated that one third of all children will sustain fractures. However, there may also be time trends in pediatric fracture incidence. When predicting future fracture incidence, it is further important to evaluate bone mass, as low bone mass is a strong predictor of fractures. Such evaluation would help the society to allocate health care resources adequately. Aims: T

Objectives The recovery after tonsil surgery is often troublesome for children and caregivers often feel insecure regarding optimal post-operative care for their children at home. The aim was to study what the current literature reports regarding the effect of post-operative telephone counselling and Internet support on pain and recovery after paediatric tonsil surgery. Method A systematic literat

While Sweden is positioned as one of the most gender equal countries in the world, survey-reported rates of intimate partner violence against women (IPVAW) are here among the highest in the EU. This apparently contradictory co-existence of high levels of gender equality and of IPVAW rates in Sweden and other Nordic countries, which has been termed the Nordic Paradox, has hitherto not been adequate

Pollinering med hjälp av vilda insekter gynnar pollineringsberoende grödor. Anläggning och bevarande av pollinatörsvänliga habitat är därför en investering som kan öka avkastningen i jordbruket. Pollinerare är mobila organismer som rör sig över större avstånd i landskapet. Därför kan ett habitat vara till nytta inte bara för den jordbrukare som förvaltar det, utan även för gårdar runtomkring. Vi u

Denna avhandling utforskar den meta-etiska frågan: Vilka egenskaper krävs av ett normativt kritiskt begrepp så att det både kan (a) härledas från den sociala faktiska verkligheten av gällande normer, praktiker och institutioner i ett givet samhälle och (b) vara utgångpunkt för radikal kritik? Radikal kritik förstås i avhandlingen som en kritik bortom anklagelser om partiskhet gentemot det rådande.This thesis explores the meta-ethical question: What properties would be required of a normative critical concept in order for it to be (a) derived from the social facticity of prevailing norms, practices and institutions in a given society and (b) still be capable of informing radical critique? This thesis takes radical critique to mean one that escapes all charges of status quo biases and thus t

In optoelectronic devices such as solar cells and photodetectors, a portion of electron-hole pairs is generated as so-called hot carriers with anexcess kinetic energy that is typically lost as heat. The long-standing aim to harvest this excess energy to enhance device performance hasproven to be very challenging, largely due to the extremely short-lived nature of hot carriers. Efforts thus focus o

The WORLD7 model was used to make an assessment for the sustainable metal usage and the resources available within the planetary limits to human society, in order to estimate demands on recycling and maximum metal consumption per capita for different metals. The metals were selected for their importance in society. The calculations of critical metal use show that we have substantial metal usage ab

Knowledge of the long relationship between gender equality and economic growth is hampered by the lack of information and resources on the various dimensions of gender equality. This paper is a first attempt to assess the size of the gender gap and investigate its relationship with economic growth from a historical perspective. Exploiting a unique census-based dataset of 86 French counties in the

Agroforestry systems, where productive trees are integrated into agricultural land, can deliver benefits to biodiversity, natural pest control, and pollination, but the effects are highly variable. Recent advances in our understanding of flower strips in agricultural systems suggest that the management of the tree row understorey could be an important contributor to this variation. Here, we compar

This article addresses supranational governance of EU criminal justice agencies from the perspective of the various agencies of policy and rulemaking who have contributed to the impressive developments in the field of EU criminal law. Taking as a working hypothesis the happenstance and haphazard character of this field of policy and law, it suggests that there is an absence of design. In the discu