The rapid advances in life science, including the sequencing of the human genome and numerous other techiques, has given an extraordinary ability to aquire data on biological systems and human disease. Even so, drug development costs are higher than ever, while the rate of new approved treatments is historically low. A potential explanation to this discrepancy might be the difficulty of understand

This study introduces a corpus of 260 naturalistic human nonlinguistic vocalizations representing nine emotions: amusement, anger, disgust, effort, fear, joy, pain, pleasure, and sadness. The recognition accuracy in a rating task varied greatly per emotion, from 70% for amusement, pleasure, fear, and sadness. In contrast, the raters’ linguistic–cultural group had no effect on recognition accuracy:

All animals and some bacteria can synthesize linear polysaccharides with a backbone of repeating disaccharideunits, called glycosaminoglycans (GAGs). The GAGs are either attached to a protein core, as in proteoglycans (PGs), or exist as free polymer chains, as in hyaluronan. One of the most common types of GAGs is chondroitin/dermatan sulfate (CS/DS), where the repeating disaccharide backbone consAll animals and some bacteria can synthesize linear polysaccharides with a backbone of repeating disaccharideunits, called glycosaminoglycans (GAGs). The GAGs are either attached to a protein core, as in proteoglycans (PGs), or exist as free polymer chains, as in hyaluronan. One of the most common types of GAGs is chondroitin/dermatan sulfate (CS/DS), where the repeating disaccharide backbone cons

This volume provides an overview of applications of conceptual spaces theory, beginning with an introduction to the modeling tool that unifies the chapters. The first section explores issues of linguistic semantics, including speakers negotiation of meaning. Further sections address computational and ontological aspects of constructing conceptual spaces, while the final section looks at philosophi

Background: Due to a lack of coordination of care flow events and uncertain capacity coordination, long patient waiting times for patients arise, entailing a medical risk and contributing towards capacity being utilized less effectively. Healthcare services are often said to be crucial to coordinate in order to create equally good availability for care-seekers. Could healthcare matching become the

Development Communication and Public Diplomacy are twin products of U.S. political science and Cold War foreign policy. As contemporary diplomatic and development policies continue to converge, new ways of interpreting the relationship between the fields are necessary. This article analyses the 2 fields' emergence out of modernization policy and their reliance on a common conception of process: na

Practitioners and scholars are increasingly aware that an array of new actors, communication technologies, agendas and expectations are changing the institution of diplomacy. How diplomatic actors are known and experienced through their representation assumes an increasingly important, and uncertain, role. This article argues that these changes to the field should be considered in terms of the shi

The notion of legacy was intrinsic to London’s 2012 bid, drawing upon the Olympic spirit in the form of personal challenges designed to motivate and mobilize individuals and communities in Britain and around the world. However, with the economic crisis and change in government in 2010, a distinct discourse of economic legacy also emerged. This increasingly saw the citizen mobilization associated w

This volume originated out of a discussion with the BritishCouncil a few years ago. In light of changes to their grant-in-aidin 2010, nearly two thirds of their governmental funding is nowcomprised of Official Development Assistance (oda). I asked whatdifference there was between the work that was conducted as culturalrelations and the work that was budgeted as aid. The answer wasthat the same pro

A common approach to the conservation of farmland biodiversity and the promotion of multifunctional landscapes, particularly in landscapes containing only small remnants of non-crop habitats, has been to maintain landscape heterogeneity and reduce land-use intensity. In contrast, it has recently been shown that devoting specific areas of non-crop habitats to conservation, segregated from high-yiel

The article contains an edition, Swedish translation and study of a fifteenth-century Easter sermon written in Latin at the Birgittine Abbey of Vadstena, in a postil produced for the curate of Björkvik, who, we may presume, used it as a resource when preparing vernacular sermons for his parishioners. The study is not simply an introduction and historical commentary. Rather, it proceeds from the ho

OBJECTIVES: To evaluate serum creatinine (s-creatinine) and serum cystatin C (s-cystatin C) levels and estimated glomerular filtration rate (eGFR) at different time points as predictors for mortality in patients undergoing coronary artery bypass grafting (CABG).METHODS: A total of 1638 patients undergoing elective CABG were studied prospectively over a median follow-up of 3.5 years (range, 2.0-5.0

In order to maximize their fitness, individuals aim at choosing territories offering the most appropriate combination of resources. As population size fluctuates in time, the frequency of breeding territory occupancy reflects territory quality. We investigated the relationships between the frequency of territory occupancy (2002-2009) vs. habitat characteristics, prey abundance, reproductive succes

Small-angle X-ray scattering (SAXS) is an indispensable tool in structural investigations of self-assembled colloidal crystals and colloidal liquid crystals. This paper reviews recent studies of the particle shape effects on the crystal structure as revealed by SAXS. Rod-like, plate-like, biaxial board-like as well as cubic-like shapes are discussed. Since relatively large, (sub)micron particles a

Sown flower strips are increasingly implemented within agri-environment schemes (AES) to increase functional biodiversity and ecosystem services such as pollination or natural pest control, but their effectiveness in achieving these goals remains poorly studied. We tested the performance of experimentally sown annual flower strips specifically designed to promote natural enemies of aphids and thei

BACKGROUND: About 20% of adolescents experience substantial mental health problems after bariatric surgery.OBJECTIVES: The aim of this study was to explore differences between adolescents with poor mental health (PMH) 2 years after surgery and those with average/good mental health.SETTING: Three university hospitals in Sweden.METHODS: Mental health and health-related quality of life were assessed