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A comparative study found that a seven-year school-based exercise programme increased physical activity levels in both sexes

Aim: This study assessed whether a Swedish school-based exercise intervention programme could increase total physical activity. Methods: We followed up 228 children who started school in 1998-2000 seven years later, when they had reached a mean age of 14.8. The 152 children (59% boys) at the intervention school did 200 minutes of physical education per week during that period, and the 76 children

Outcome and Complications Using Negative Pressure Wound Therapy in the Groin for Perivascular Surgical Site Infections after Vascular Surgery

Background: The aim of this study was to investigate graft preservation, major bleeding, and reinfection rate using negative pressure wound therapy (NPWT) for perivascular surgical site infections (SSIs) in the groin after vascular surgery and factors associated with failure of treatment. Methods: Retrospective data were collected during 2004-2015. Failure of wound treatment was defined as a wound

Lightweight Dispatcher Constructions for Control Flow Flattening

The objective of control flow obfuscation is to protect the program control flow from analysis. A technique called control flow flattening addresses static analysis by hiding edges between basic blocks in a program and introduces a dispatcher block that determines the execution order of the randomized blocks.In this paper we propose a novel flattening construction and lightweight dispatchers that The objective of control flow obfuscation is to protect the program control flow from analysis. A technique called control flow flattening addresses static analysis by hiding edges between basic blocks in a program and introduces a dispatcher block that determines the execution order of the randomized blocks.In this paper we propose a novel flattening construction and lightweight dispatchers that

Patentability of methods of human enhancement

This article explores how to apply patentability rules to human enhancement, particularly focusing on Article 53(c) of the European Patent Convention (EPC).The global size and value of the cosmetic and wellness market and industry allow for the prediction of considerable market potential for human enhancement. Patents will be instrumental for companies to protect investment in innovation and tap i

Economic Justification of Patents and Exceptions to Patentability

The present article is the conclusion of a review of economic justifications for patent rights conducted with the objective of determining whether such arguments are per se capable of sustaining the existence of a different patentability regime for inventions of methods for treatment and diagnostic methods (art.53 (c) European Patent Convention). It starts by exploring the normative background and

Familial associations of lymphoma and myeloma with autoimmune diseases

Many B-cell neoplasms are associated with autoimmune diseases (AIDs) but most evidence is based on a personal rather than a family history of AIDs. Here we calculated risks for non-Hodgkin lymphoma (NHL), Hodgkin lymphoma (HL) and multiple myeloma (MM) when family members were diagnosed with any of 44 different AIDs, or, independently, risk for AIDs when family members were diagnosed with a neopla

Sudden cardiac death among the young in Sweden from 2000 to 2010 : An autopsy-based study

Aims To study the incidence and aetiology of sudden cardiac death (SCD) in 1- to 35-year-olds in Sweden from 2000 to 2010. Methods and results We used the database of the Swedish National Board of Forensic Medicine and the Swedish Cause of Death Registry and identified SCD cases by review of forensic files and death certificates. We identified 552 individuals with SCD in 1- to 35-year-olds; 156 (2

Economic Evaluations of Organ Transplantations : A Systematic Literature Review

The purpose of this study is threefold; 1) to establish the current level of knowledge regarding cost-effectiveness of organ transplantation, 2) to identify knowledge gaps, and 3) to suggest a framework for future studies. A systematic literature review of economic evaluations of transplantations of solid organs was conducted in October 2010. Economic evaluations published since 2000 and reviews p

Lifetime attributable risk as an alternative to effective dose to describe the risk of cancer for patients in diagnostic and therapeutic nuclear medicine

The aim of this study is to implement lifetime attributable risk (LAR) predictions of cancer for patients of various age and gender, undergoing diagnostic investigations or treatments in nuclear medicine and to compare the outcome with a population risk estimate using effective dose and the International Commission on Radiological Protection risk coefficients. The radiation induced risk of cancer

Preoperative Quantitative MR Tractography Compared with Visual Tract Evaluation in Patients with Neuropathologically Confirmed Gliomas Grades II and III : A Prospective Cohort Study

Background and Purpose. Low-grade gliomas show infiltrative growth in white matter tracts. Diffusion tensor tractography can noninvasively assess white matter tracts. The aim was to preoperatively assess tumor growth in white matter tracts using quantitative MR tractography (3T). The hypothesis was that suspected infiltrated tracts would have altered diffusional properties in infiltrated tract seg

Reduced corneal nerve fiber density in type 2 diabetes by wide-area mosaic analysis

PURPOSE. To determine if corneal subbasal nerve plexus (SBP) parameters derived from widearea depth-corrected mosaic images are associated with type 2 diabetes. METHODS. One hundred sixty-three mosaics were produced from eyes of 82 subjects by laserscanning in vivo confocal microscopy (IVCM). Subjects were of the same age, without (43 subjects) or with type 2 diabetes (39 subjects). Mosaic corneal

Familial Aggregation of Aortic Valvular Stenosis : A Nationwide Study of Sibling Risk

Background - Aortic valvular stenosis (AS) is the most common cause of cardiac valvular replacement surgery. During the last century, the pathogenesis of AS has undergone transitions in developed countries, from rheumatic heart disease to a degenerative calcific pathogenesis. Although a familial component has been described for a subset of cases with a bicuspid valve, data are limited on the overa

Communicating for Funding

Kapitlet beskriver en övning lämplig för studenter i kurser om socialt entreprenörskap. Övningen tillämpar tekniker för kommunikation för att erhålla donationer från olika intressenter.

Andraspråket i utveckling

En av utmaningarna för lärare är att känna igen språkfel som en del av språkutvecklingen. Eftersom normen i klassrummet ofta är språklig korrekthet kan det vara svårt att urskilja utvecklingen. Synen på inlärarspråket som ett eget språk snarare än en sämre variant av målspråket samt kunskap om typiska drag i inlärarspråket ökar möjligheterna att se den utveckling som faktiskt sker hos eleverna, vi

Right ventricular speckle tracking assessment for differentiation of pressure- versus volume-overloaded right ventricle

BACKGROUND: Right ventricular (RV) dysfunction may be caused by either pressure or volume overload. RV function is conventionally assessed with echocardiography using tricuspid annular plane systolic excursion (TAPSE), RV fractional area change (RVFAC), tricuspid lateral annular systolic velocity (S') and RV index of myocardial performance (RIMP). The purpose of this study was to evaluate whether