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A Disentangled VAE-BiLSTM Model for Heart Rate Anomaly Detection

Cardiovascular diseases (CVDs) remain a leading cause of death globally. According to the American Heart Association, approximately 19.1 million deaths were attributed to CVDs in 2020, in particular, ischemic heart disease and stroke. Several known risk factors for CVDs include smoking, alcohol consumption, lack of regular physical activity, and diabetes. The last decade has been characterized by

Remembering Ross Leadbetter: some personal reflections

Ross Leadbetter had had a broad and deep influence on the development of proba-bilistic and statistical theory of extreme values and on the application of extreme-value methods. He has been an inspiration and a friend for many of us. This edito-rial collects thirteen personal recollections of Ross and his work. An account of hiscareer and some of his work can be found in the IMS Obituary “Ross Lea

Musikalisk trans - vägar mot ett accepterande lyssnande

Title: Musical Trance - Paths towards listening with acceptance Why do I perceive music the way I do? Can I evolve an ability to play with more emotion and how does this relate to my way of listening? To learn more about the experience of music I investigated my own critical way of listening, came up with tools to bypass the analytical mind and studied how my musicianship can benefit from this. In

PSI-PSYCHO SCHIZOPHRENIA IMAGING- Hjärnavbildning vid Schizofreni. : Del 4: Ämnesomsättning och Schizofreni

4-5.1 Sammanfattning av Glutamat och GABA vid Schizofreni1H-MRS och kronisk schizofreni1H-MRS visar att alla Schizofreni patienter hade ett signifikant lägre N-AcetylAsparagin-syra(NAA) till Kreatin(Cr) nivåförhållande i frontalloben än kontrollerna. Resultaten indikerar att det finns ett samband mellan det Glutamat-erga systemet och patofysiologin vid Schizofreni. (Szulc et al., 2013).GABA och gl

Geospatial mapping of surgical systems for earthquake emergency planning in Guerrero, Mexico : an ecological study

BACKGROUND: Accessibility to surgical services can impact earthquake preparedness and response. We aimed to estimate the population with timely access to surgical care in Guerrero, a Mexican state with high tectonic activity, and identify populations at risk in the event of an earthquake.METHODS: We conducted an ecological study using open government data. We extracted data from Guerrero municipal

Exploring Monoclonal Antibody Action Against the Group A Streptococcal M Protein

Group A Streptococcus (GAS) is a significant human pathogen that has developed multipleimmune evasion mechanisms to counter the host immune response. One of these mechanisms involvesthe production of the M protein, which, amongst other things, acts as an anti-phagocytic factor and canbind host proteins. Another is the ability of M protein to bind a human protein called fibronectin (Fn). Thisprotei

Fructan Enzymes in Microbes and Plants : Structure, Function, and Product Formation

Fructans—fructose-based oligo- or polysaccharides—are de novo synthesized from sucrose by transfructosylating enzymes of microorganisms and plants. Fructan-producing enzymes belong to glycoside hydrolase families 32 and 68. Levansucrases, inulosucrases, some invertases, sucrose:sucrose 1-fructosyl transferases, fructan:fructan 1-fructosyl transferases, sucrose:fructan 6-fructosyl transferases and

Night for Day

Night for Day uses the fake relationship between a mother and a son to think about what would happen if a communist revolutionary gave birth to a techno utopian, if gender as performitivity was thought through the lens of women making the political decision to live clandestinely in Portugal for a larger part of the 20th century and if the “Last Woman” were the fem bot from The Tales of Hoffman.Com

In old men Scheuermann’s disease is not associated with neck or back pain : a Swedish cohort study

Background and purpose — Scheuermann’s disease is characterized by kyphosis and frequently mild back pain. As the level of kyphosis may progress over time, also the level of pain may increase. We evaluated the prevalence of Scheuer-mann’s disease, and their pain, in Swedish elderly men. Patients and methods — The Osteoporotic Fractures in Men (MrOS) Study Sweden (n = 3,014) is a population-based p

Galectin-3 shapes toxic alpha-synuclein strains in Parkinson’s disease

Parkinson’s Disease (PD) is a neurodegenerative and progressive disorder characterised by intracytoplasmic inclusions called Lewy bodies (LB) and degeneration of dopaminergic neurons in the substantia nigra (SN). Aggregated α-synuclein (αSYN) is known to be the main component of the LB. It has also been reported to interact with several proteins and organelles. Galectin-3 (GAL3) is known to have a

Abū Bakr Muḥammad ibn Zakariyyāʾ al-Rāzī: On Phlebotomy : Edition, translation and commentary

The objective of this study is to present a text-critical edition of the medieval treatise Maqāla fī l-Faṣd, ‘On Phlebotomy’, attributed to Abū Bakr Muḥammad ibn Zakariyyāʾ al-Rāzī (865-925), a prominent physician and scholar known especially for his expertise in medicine. His contributions as a distinguished medical author and devoted clinician earned him recognition in both Arabic and Latin medi

Direct Determination of the Rate of Intersystem Crossing in a Near-IR Luminescent Cr(III) Triazolyl Complex

A detailed understanding of the dynamics of photoinduced processes occurring in the electronic excited state is essential in informing the rational design of photoactive transition-metal complexes. Here, the rate of intersystem crossing in a Cr(III)-centered spin-flip emitter is directly determined through the use of ultrafast broadband fluorescence upconversion spectroscopy (FLUPS). In this contr

Longitudinal Assessment of Circulating Tumor Cells and Outcome in Small Cell Lung Cancer : A Sub-Study of RASTEN—A Randomized Trial with Low Molecular Weight Heparin

Circulating tumor cells (CTCs) may provide a liquid biopsy approach to disease monitoring in small cell lung cancer (SCLC), a particularly aggressive tumor subtype. Yet, the prognostic role of CTCs during and after treatment in relation to baseline remains ill-defined. Here, we assessed the value of longitudinal CTC analysis and the potential of low-molecular-weight heparin (LMWH) to reduce CTC ab

Absence that fades after a while

Youngjae Lih’s emotional and perception-altering installation Multiplicity to Singularity, then Singularity to Multiplicity explores history as natural duration measured by light frequency, with sound, abstraction and instruments meant to represent nature’s rhythms. It stems from the way in which two industrial producers of color filters, Lee and Rosco, have coded the visible world in shades of li

Magnetic resonance Spectrum simulator (MARSS), a novel software package for fast and computationally efficient basis set simulation

The aim of this study was to develop a novel software platform for the simulation of magnetic resonance spin systems, capable of simulating a large number of spatial points (1283 ) for large in vivo spin systems (up to seven coupled spins) in a time frame of the order of a few minutes. The quantum mechanical density-matrix formalism is applied, a coherence pathway filter is utilized for handling u

Theoretical description of modern 1 H in Vivo magnetic resonance spectroscopic pulse sequences

This article reviews the most commonly used modern sequences designed to confront the two major challenges of in vivo magnetic resonance spectroscopy (MRS): spatial localization and metabolic specificity. The purpose of this review article is to provide a deeper and clearer understanding of the underlying mechanisms by which all modern MRS sequences operate. A descriptive explanation, consistent p

FlexPES : a versatile soft X-ray beamline at MAX IV Laboratory

FlexPES is a soft X-ray beamline on the 1.5 GeV storage ring at MAX IV Laboratory, Sweden, providing horizontally polarized radiation in the 40-1500 eV photon energy range and specializing in high-resolution photoelectron spectroscopy, fast X-ray absorption spectroscopy and electron-ion/ion-ion coincidence techniques. The beamline is split into two branches currently serving three endstations, wit

The evolution of climate justice claims in global climate change negotiations under the UNFCCC

A growing body of research suggests that the global conception of climate change is increasingly taking a justice-focus. However, the justice-framings of different actors in the UNFCCC process and their evolution have not yet been examined. We conduct a critical discourse analysis of climate justice claims of state and non-state actors in COP15, COP19, COP21 and COP24 which are key moments for cli