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Dynamic Server Provisioning with Queue Stabilization in Data Centres

When load balancing data centres with all serversactive to serve jobs, the result can be excessive energy usage. Onthe other hand, using dynamic server provisioning, the numberof servers that serve requests can be reduced by turning off idleservers and thereby save energy. However, such a scheme, usuallyincreases the risk of instability of server queues. In this work,we analyze the trade-off betwe

Hepcidin levels and gastric cancer risk in the EPIC-EurGast study

Hepcidin is the main regulator of iron homeostasis and dysregulation of proteins involved in iron metabolism has been associated with tumorogenesis. However, to date, no epidemiological study has researched the association between hepcidin levels and gastric cancer risk. To further investigate the relationship between hepcidin levels and gastric cancer risk, we conducted a nested case-control stud

Lead(ii) soaps : Crystal structures, polymorphism, and solid and liquid mesophases

The long-chain members of the lead(ii) alkanoate series or soaps, from octanoate to octadecanoate, have been thoroughly characterized by means of XRD, PDF analysis, DSC, FTIR, ssNMR and other techniques, in all their phases and mesophases. The crystal structures at room temperature of all of the members of the series are now solved, showing the existence of two polymorphic forms in the room temper

Redox-Driven Migration of Copper Ions in the Cu-CHA Zeolite as Shown by the InSitu PXRD/XANES Technique

Using quasi-simultaneous insitu PXRD and XANES, the direct correlation between the oxidation state of Cu ions in the commercially relevant deNOx NH3-SCR zeolite catalyst Cu-CHA and the Cu ion migration in the zeolitic pores was revealed during catalytic activation experiments. A comparison with recent reports further reveals the high sensitivity of the redox-active centers concerning heating rates

Monomeric and fibrillar α-synuclein exert opposite effects on the catalytic cycle that promotes the proliferation of Aβ42 aggregates

The coaggregation of the amyloid-β peptide (Aβ) and α-synuclein is commonly observed in a range of neurodegenerative disorders, including Alzheimer’s and Parkinson’s diseases. The complex interplay between Aβ and α-synuclein has led to seemingly contradictory results on whether α-synuclein promotes or inhibits Aβ aggregation. Here, we show how these conflicts can be rationalized and resolved by de

Trends in treatment with antipsychotic medication in relation to national directives, in people with dementia - a review of the Swedish context

Background: The aim of this study was to explore trends in treatment with antipsychotic medication in Swedish dementia care in nursing homes as reported in the most recent empirical studies on the topic, and to relate these trends to directives from the national authorities. Methods: The study included two scoping review studies based on searches of electronic databases as well as the Swedish dire

Sustained versus standard inflations during neonatal resuscitation to prevent mortality and improve respiratory outcomes

Background: At birth, infants' lungs are fluid-filled. For newborns to have a successful transition, this fluid must be replaced by air to enable effective breathing. Some infants are judged to have inadequate breathing at birth and are resuscitated with positive pressure ventilation (PPV). Giving prolonged (sustained) inflations at the start of PPV may help clear lung fluid and establish gas volu

Clonal Hematopoiesis and risk of atherosclerotic cardiovascular disease

BACKGROUND Clonal hematopoiesis of indeterminate potential (CHIP), which is defined as the presence of an expanded somatic blood-cell clone in persons without other hematologic abnormalities, is common among older persons and is associated with an increased risk of hematologic cancer. We previously found preliminary evidence for an association between CHIP and atherosclerotic cardiovascular diseas

Skydd för berättigade förväntningar i svensk förvaltningsrätt? – Negativ rättskraft, EU-rätt och styrning av förvaltningen

En grundläggande fråga i den allmänna förvaltningsrätten är var gränserna ska gå för möjligheten att ändra meddelade beslut. I svensk förvaltningsrätt har denna fråga traditionellt besvarats med hjälp av principer om (förvaltningsrättslig) negativ rättskraft. I EU-rätten har det däremot under inflytande av andra medlemsstaters rättstraditioner utvecklats en unionsrättslig princip om skydd för berä

High contrast sensitivity for visually guided flight control in bumblebees

Many insects rely on vision to find food, to return to their nest and to carefully control their flight between these two locations. The amount of information available to support these tasks is, in part, dictated by the spatial resolution and contrast sensitivity of their visual systems. Here, we investigate the absolute limits of these visual properties for visually guided position and speed con

En ny gudinna för en ny tid : Ovidius och Hersilias metamorfos

This article argues that the Roman poet Ovid in his Metamorphoses invented the apotheosis of Hersilia into the goddess Hora as a way to flatter the empress Livia. There are compelling parallels between the words used to describe Hersilia and Livia in Ovid’s poetry. Furthermore, Hersilia was, according to the legend, a Sabine woman who married Romulus, the founder of Rome. Livia was born into the C

Agility in entrepreneurial projects

Managing entrepreneurship is of importance for the society, for organizations and for the individual. It is not enough with knowledge and skills relating to the idea behind entrepreneurship. The entrepreneur must have knowledge and skills to manage the entrepreneurial process. The purpose of this paper is to put forward for agile project management as an appropriate way to manage an entrepreneuria

Four-dimensional in vivo X-ray microscopy with projection-guided gating

Visualizing fast micrometer scale internal movements of small animals is a key challenge for functional anatomy, physiology and biomechanics. We combine phase contrast tomographic microscopy (down to 3.3 μm voxel size) with retrospective, projection-based gating (in the order of hundreds of microseconds) to improve the spatiotemporal resolution by an order of magnitude over previous studies. We de

Simultaneous dual-energy X-ray stereo imaging

Dual-energy or K-edge imaging is used to enhance contrast between two or more materials in an object and is routinely realised by acquiring two separate X-ray images each at different X-ray wavelength. On a broadband synchrotron source an imaging system to acquire the two images simultaneously was realised. The single-shot approach allows dual-energy and stereo imaging to be applied to dynamic sys

Interferon Regulatory Factor 5 Controls Necrotic Core Formation in Atherosclerotic Lesions by Impairing Efferocytosis

BACKGROUND—: Myeloid cells are central to atherosclerotic lesion development and vulnerable plaque formation. Impaired ability of arterial phagocytes to uptake apoptotic cells (efferocytosis), promotes lesion growth and establishment of a necrotic core. The transcription factor Interferon Regulatory Factor (IRF)-5 is an important modulator of myeloid function and programming. We sought to investig