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HLA class I maturation - in the presence and absence of tapasin

Popular Abstract in Undetermined Vårt immunförsvar består av molekyler, celler, och barriärer som har till uppgift att hålla oss friska genom att avlägsna eller stänga ute virus och skadliga mikroorganismer. På alla kärnförsedda celler i vår kropp sitter en stor mängd MHC klass I-molekyler, strukturer som kan liknas vid korgar. I varje korg ligger en peptid som är ett fragment av något som finns iHuman leukocyte antigen class I (HLA-I) molecules are present on all nucleated cells and present the cell content to cytotoxic T lymphocytes in the form of peptides. Maturation of HLA-I occurs in the endoplasmic reticulum and results in stable peptide-HLA-I complexes, in the presence of proper quality control. For proper peptide binding most HLA-I molecules interact with the peptide-loading comple

Object-Oriented Modeling and Predictive Control of the Moisture Content in Paper Production

Drying is an important process in paper manufacturing, where steam heated cylinders are used to dry paper. Control of the moisture content is accomplished by adjusting the steam pressure in the cylinders. This paper presents a nonlinear dynamic model, based on heat and mass balances for steam, cylinder, and paper. It is implemented in the object-oriented modeling language Modelica and is used to e

Propagation in bianisotropic media - reflection and transmission

In this paper a systematic analysis that solves the wave propagation problem in a general bianisotropic, stratified media is presented. The method utilizes the concept of propagators, and the representation of these operators is simpli- fied by introducing the Cayley-Hamilton theorem. The propagators propagate the total tangential electric and magnetic fields in the slab and only outside the slab

New Hopes for Democracy or a Pirated Elite? Swedish Social Media Users and Political Mobilisation.

In this study, a group of Swedish social media users – politically active as well as “unpolitical” users – are interviewed in focus groups as well as individually about their attitudes towards online political participation, providing a deeper, more informed view of how social media participation works. Sweden, with its high levels of voluntary participation and with an avant-garde position in Int