This paper investigates the use of self-funded commitment contracts to support individuals in achieving their goals of increased physical activity. We compare the effect of soft (non-incentivised) commitment contracts with hard (incentivised) contracts using a randomised experiment with 1629 members of a large gym in Stockholm, Sweden. We find a significant positive impact of being offered a hard

Molecular oxygen is essential for most living species. Consequently, hypoxic or ischemic conditions are major cellular stressors and prominent pathological features in ischemic stroke. Stroke is a global health problem and remains the second leading cause of death or disability worldwide. Current management of the disease focuses on rapid reperfusion by thrombolysis or thrombectomy but these thera

Flank wear VBmax remains one of the most essential and used metrics for measuring tool wear. VBmax is used to characterize tool wear rate, machinability of materials, the quality of machined surface. While VBmax measures the size of wear scar, the shape of the tool wear remains less used but not the least applicable for such characterization. However, quantification of the wear shape requires a mo

OBJECTIVE: To explore how lifestyle and demographic, socioeconomic and disease-related factors are associated with supervised exercise adherence in an osteoarthritis (OA) management programme and their ability to explain exercise adherence.METHODS: A cohort register-based study on participants from the 'Swedish Osteoarthritis Registry' who attended the exercise part of a nationwide Swedish OA mana

BACKGROUND: Influenza is a contagious viral airborne disease that adds to the clinical and economic burden on the healthcare system. It could be prevented substantially by seasonal influenza vaccination. Seasonal influenza vaccine effectiveness (SIVE) varies a lot and should therefore be monitored. This report aims to update age-stratified SIVE estimates among patients hospitalized due to severe a

Immigrants from the Middle East to Sweden have a twice as high prevalence of type 2 diabetes (T2D) and obesity as native-born Swedes. Both obesity and T2D have been linked to increased incidence of cancer, cardiovascular disease (CVD) and all-cause mortality (ACM); however, data on differences between ethnicities are scarce. In a population-based cohort we aimed to study the impact of Middle Easte

Ett alternativ för att studera immunceller i cellkulturer utan djurprodukter Cancer är ett samlingsnamn för en rad olika sjukdomar som kan uppstå var som helst i människokroppen. Tillståndet kännetecknas av att tumörer bildas i en viss kroppsdel som kan spridas till andra delar. Tumörer är komplexa strukturer som inte bara innehåller cancerceller. Cancercellerna i en tumör omringas av en så-kallaThe use of cancer cell cultures, including immune cells, is essential in cancer research for developing immunotherapies in pre-clinical investigations. However, so far, a large number of animal-derived products are utilised in cell culturing, where experimental variations and reproducibility problems have been reported. Most studies have also only investigated the differentiation of monocytes into

Developing a new tool for the study of human brain development “If the human brain were so simple that we could understand it, we would be so simple that we couldn’t” physicist Emerson Pugh once said. Nevertheless, despite its complexity, researchers are trying to figure out one of the human body's most vital organs. Understanding the development of the brain is crucial to understanding how i

This article highlights how an aesthetics of religion approach generates significant new insights into well-researched textual material. It does so by looking at Chinese Buddhist biographies focusing on how the world of smell is communicated. Academically established ways of approaching biographies elucidate their historical background and analyze narrative patterns. By looking at the Biographies

Large amounts of germline sequencing data have recently become available and we sought to compare these results with population-based family history data. Family studies are able to describe aggregation of any defined cancers in families. The Swedish Family-Cancer Database is the largest of its kind in the world, covering the Swedish families through nearly a century with all cancers in family mem