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Från Eden till Damavdelningen : studier om kvinnan i litteraturen : en vänbok till Christina Sjöblad

Under den vida rubriken Från Eden till Damavdelningen har uppsatser om kvinnan som författare, som huvudkaraktär, som objekt, som samhällshot, som mor och maka, som ung flicka, som offer, som bohem, som resenär och som naturskildrare samlats. Variationerna av uppsatsernas innehåll är stora. Som titeln antyder sträcker sig ämnena tidsmässigt från den paradisiska till den moderna tiden. Med boken vi

The Solling roof revisited - slow recovery from acidification observed and modeled despite a decade of "clean-rain" treatment

Soil chemistry under the Solling clean-rain roof was simulated using the dynamic multi-layer soil chemistry model SAFE, including sulfate adsorption. Soil was sampled in order to parameterize the pH and sulfate concentration dependent sulfate adsorption isotherm used in SAFE. Modeled soil solution chemistry was compared to the 14 year long time-series of monthly measurements of soil solution data

Quantum chemical geometry optimizations in proteins using crystallographic raw data.

A method is developed for the combination of quantum chemical geometry optimizations and crystallographic structure refinement. The method is implemented by integrating the quantum chemical software Turbomole with the crystallographic software Crystallography and NMR System (CNS), using three small procedures transferring information between the two programs. The program (COMQUM-X)is used to study

GABAB-receptor activation inhibits exocytosis in rat pancreatic {beta}-cells by G-protein-dependent activation of calcineurin.

We have investigated the regulation of hormone secretion from rat pancreatic islets by the GABAB receptors (GABABRs). Inclusion of the specific GABABR antagonist CGP 55845 in the extracellular medium increased glucose-stimulated insulin secretion 1.6-fold but did not affect the release of glucagon and somatostatin. Conversely, addition of the GABABR agonist baclofen inhibited glucose-stimulated in

Production of heterologous thermostable glycoside hydrolases and the presence of host-cell proteases in substrate limited fed-batch cultures of Escherichia coli BL21(DE3)

Metabolic stress is a phenomenon often discussed in conjunction with recombinant protein production in Escherichia coli. This investigation shows how heterologous protein production, and the presence of host cell proteases is related to: i) IPTG induction, ii) cell mass concentration at the time of induction and iii) the presence of metabolites (glutamic acid or those from TSB) during the post ind

Peptides analysis in blood plasma using on-line system of supported liquid membrane and high-performance liquid chromatography

The potential of using supported liquid membrane (SLM) technique, combined with reversed-phase high-performance liquid chromatography (RP-HPLC) has been investigated for the determination of peptides in human blood plasma. The peptides studied were (DL)Leu(DL)Phe, MetLeuPhe, GlyLeuTyr and ValGluProlleProTyr. The carrier (Aliquat 336) was incorporated in membrane phase in order to facilitate the tr

Nutrition in acute pancreatitis - influence on gut barrier and inflammatory response

Popular Abstract in Swedish Den övergripande målsättningen för projektet var att studera nuvarande vätske- och nutritionsbehandling samt effekter av tidigt insatt sondnäring och tidigt insatt normal kost vid akut bukspottkörtelinflammation (pankreatit). Företeelser som särskilt studerades var akut inflammatoriskt svar, tarmbarriär och kliniskt förlopp. Bakgrund Akut pankreatit (AP) drabbar ca 30Acute pancreatitis (AP) is associated with metabolic changes, acute inflammatory response and increased gut permeability. In AP, traditional treatment has been initial fasting on purpose to avoid activation of proteolytic enzymes and pancreatic enzyme secretion. However, enteral feeding has been suggested superior to fasting due to a proposed beneficial effect on the gut barrier function. The aim

Isotope structure of SmII as an indicator of r- vs. s-process nucleosynthesis

Aims. The isotope composition of samarium provides a previously unexploited means of determining the r- versus s-process content of e. g. metal-poor stars. The seven stable isotopes of samarium can be divided into two groups, where in one group the r- process is the dominant production mechanism, while for the second group it is the s-process that is dominant. The center-of-gravity for spectral li

No adverse events after simultaneous administration of 50 000 IU vitamin A and Bacille Calmette-Guerin vaccination to normal-birth-weight newborns in Guinea-Bissau

Objective:To determine whether the combined intervention of 50 000 IU vitamin A administered together with Bacille Calmette-Guerin (BCG) vaccination at birth was associated with adverse events, in particular bulging fontanels and adverse reactions to BCG.Subjects/Methods:From an ongoing trial, 2145 infants randomized to 50 000 IU vitamin A or placebo with BCG vaccination were recruited. Adverse ev

Joining chain-expressing and -nonexpressing B cell populations in the mouse

The diphtheria toxin A chain (DTA) was gene targeted into the Joining chain (J chain) locus to create a mouse strain selecting against J chain-expressing cells, JDTA mice. Serum immunoglobulin (Ig)M and serum IgG were reduced six to eightfold, while serum IgA was elevated 14-fold in these mice. JDTA mice were immune competent although the serum Ig response compared with wild-type mice was reduced

Fetal and perinatal risk factors for inflammatory bowel disease

Aim: To study the influence of specific factors and events during pregnancy and the perinatal period on the risk of children developing inflammatory bowel disease. Methods: Population-based national register study. Linkage between the Swedish Medical Birth Register and the Swedish Hospital Discharge Register during the period 1987 to 2000 identified 455 singleton infants who later developed inflam

H-k metrics on the diffeomorphism group of the circle

Each H-k inner product, kis an element ofN, endows the diffeomorphism group of the circle with a Riemannian structure. For kgreater than or equal to1 the Riemannian exponential map is a smooth local diffeomorphism and the length-minimizing property of geodesics holds.

Immunohistochemical Distribution of Cyclic GMP-Dependent Protein Kinase-1 in Human Prostate Tissue.

Objectives: Phosphodiesterase 5 (PDE5) inhibitors improve smooth muscle relaxation and therefore are considered for pharmacotherapy of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS). Cyclic guanosine monophosphate (cGMP) -dependent protein kinase-1 (cGKI) has been identified as one of the downstream targets for cGMP. The aim of the present study was to evaluate, by mean

Serine protease inhibitors in the upper and lower airways

Popular Abstract in Swedish Kliniska och experimentella studier har visat att proteaser och deras inhibitorer deltar i mycket hög grad i luftvägarnas fysiologi och sjukdomsutveckling. Inflammatoriska celler, såsom neutrofiler, monocyter/makrofager, epitel- och mastceller, friger olika proteaser. Det är allmänt känt att ökad produktion eller aktivitet av proteaser eller inaktivering och minskad proProteases and their inhibitors are implicated in the physiology and pathology of the airways. Protease inhibitors include those produced locally, such as secretory leukocyte protease inhibitor (SLPI), and those produced mainly by the liver that can reach the airways via passive diffusion, such as alpha1-antitrypsin (AAT). SLPI is a significant component of the anti-neutrophil elastase shield in th