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Photocatalytic nanoparticles – From membrane interactions to antimicrobial and antiviral effects

As a result of increasing resistance among pathogens against antibiotics and anti-viral therapeutics, nanomaterials are attracting current interest as antimicrobial agents. Such materials offer triggered functionalities to combat challenging infections, based on either direct membrane action, effects of released ions, thermal shock induced by either light or magnetic fields, or oxidative photocata

Chiral Selectivity of Secondary Nucleation in Amyloid Fibril Propagation

Chirality is a fundamental feature of asymmetric molecules and of critical importance for intermolecular interactions. The growth of amyloid fibrils displays a strong enantioselectivity, which is manifested as elongation through the addition of monomers of the same, but not opposite, chirality as the parent aggregate. Here we ask whether also secondary nucleation on the surface of amyloid fibrils,

Transcriptome sequencing provides evidence of genetic assimilation in a toad-headed lizard at high altitude

Understanding how organisms adapt to the environment is a compelling question in modern evolutionary biology. Genetic assimilation provides an alternative hypothesis to explain adaptation, in which phenotypic plasticity is first triggered by environmental factors, followed by selection on genotypes that reduce the plastic expression of phenotypes. To investigate the evidence of genetic assimilatio

My memories of ahmed zewail - from a snowy northern Sweden to the nobel prize

In the summer of 1993, two Russian scientists from the Institute of Physics in Nizhny Novgorod drove the 1, 934 km to Umeå, where I was based at that time, in their red Lada car loaded with a home-built Ti:Sa laser. Within a few days, the laser was put in operation, pumped by a small argon-ion laser, and produced stable -100 fs pulses at 790 nm. These pulses were applied to our favorite topic at t

A global survey of emergency department responses to the COVID-19 pandemic

Introduction: Emergency departments (ED) globally are addressing the coronavirus disease 2019 (COVID-19) pandemic with varying degrees of success. We leveraged the 17-country, Emergency Medicine Education & Research by Global Experts (EMERGE) network and non-EMERGE ED contacts to understand ED emergency preparedness and practices globally when combating the COVID-19 pandemic. Methods: We elect

Exploring associations of housing, relocation, and active and healthy aging in sweden : Protocol for a prospective longitudinal mixed methods study

Background: While housing and neighborhood features have the potential to impact opportunities for active aging, there is a lack of knowledge related to how older people reason regarding their housing situation and how housing and fulfillment of relocation are associated with active and healthy aging. Objective: The objectives of Prospective RELOC-AGE are to study housing choices and relocation an

Enkel senförflyttning kan ge ökad funktion vid droppfot efter stroke

Droppfot leder till försämrad gångförmåga och balans. Patienter med droppfot beskriver en påtagligt reducerad livskvalitet, och många har behov av såväl gånghjälpmedel som en ortos. Patienter med stroke har ofta en symtomgivande droppfot.Droppfot kan behandlas kirurgiskt med bland annat senförflyttningar med gott resultat. En multicenterstudie pågår där syftet är att utvärdera effekten av kirurgisFoot drop (FD) can be caused by a variety of diseases and injuries. FD leads to walking difficulties and reduced balance which also can lead to a higher risk of falling. Patient with a stroke often have an equinovarus deformity of the foot together with the DF. There is a need to optimize and standardize the treatment for patients with FD across different medical specialities. Surgical interventio

Pharmaceutical composition with improved bioavailability of inositol phosphate

The invention relates to an inositol phosphate containing pharmaceutical composition which comprises an aliphatic ester or ether for improvement of the bioavailability of the inositol phosphate in mammals including man at non-parenteral administration. The invention also covers the use of at least one aliphatic ester or ether compound for the preparing of an inositol phosphate containing medicamen

The variability in Salix BVOC emissions and possible consequences for managed SRC plantations

Willow (Salix spp.) trees have been used commercially since the 1980s to produce renewable energy. Some benefits with these trees are that they can clean soil from heavy metals, reduce the risk of nutrient leakage and eutrophication. They could be an alternative to reduce carbon dioxide emissions from fossil fuel, but they are known to emit high rates of biogenic volatile organic compounds (BVOCs)

A Virtual Smash Room for Venting Frustration or Just Having Fun: Participatory Design of Virtual Environments in Digitally Reinforced Cancer Rehabilitation

Background:Cancer rehabilitation is central for helping patients and relatives create a functional everyday life based on the changes in life conditions. The needs are highly individual and include physical, mental, and social challenges. Cancer rehabilitation programs offer coping strategies, including guidelines on how to handle emotions.Objective:This paper presents a participatory design activ