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Assessment of Cesarean hysterotomy scar before pregnancy and at 11–14 weeks of gestation : a prospective cohort study
Objective: To compare the appearance and measurement of Cesarean hysterotomy scar before pregnancy and at 11–14 weeks in a subsequent pregnancy. Methods: This was a prospective cohort study of women aged 18–35 years who had one previous Cesarean delivery (CD) at ≥ 37 weeks. Women were examined with saline contrast sonohysterography 6–9 months after CD. A scar defect was defined as large if scar th
Virological failure and all-cause mortality in HIV-positive adults with low-level viremia during antiretroviral treatment
Although most HIV-infected individuals achieve undetectable viremia during antiretroviral therapy (ART), a subset have low-level viremia (LLV) of varying duration and magnitude. The impact of LLV on treatment outcomes is unclear. We investigated the association between LLV and virological failure and/or all-cause mortality among Swedish patients receiving ART. Methods HIV-infected patients from tw
Diversity and functions of intestinal mononuclear phagocytes
The intestinal lamina propria (LP) contains a diverse array of mononuclear phagocyte (MNP) subsets, including conventional dendritic cells (cDC), monocytes and tissue-resident macrophages (mÏ †) that collectively play an essential role in mucosal homeostasis, infection and inflammation. In the current review we discuss the function of intestinal cDC and monocyte-derived MNP, highlighting how these
Registries on peritoneal surface malignancies throughout the world, their use and their options
Aim: The treatment of peritoneal surface malignancies ranges from palliative care to full cytoreductive surgery (CRS) and heated intraperitoneal chemotherapy, HIPEC. Ongoing monitoring of patient recruitment and volume is usually carried out through dedicated registries. With multiple registries available worldwide, we sought to investigate the nature, extent and value of existing worldwide CRS an
How badly did it hit? Self-assessed emotional shock upon prostate cancer diagnosis and psychological well-being : a follow-up at 3, 12, and 24 months after surgery
Background: We were interested in examining if there was a link between self-assessed emotional shock by prostate cancer diagnosis and psychological well-being at 3, 12, and 24 months after surgery. Material and methods: Information was derived from patients participating in the LAPAroscopic Prostatectomy Robot Open (LAPPRO) trial, Sweden. We analyzed the association between self-assessed emotiona
Callous-Unemotional Traits, Harm-Effect Moral Reasoning, and Bullying Among Swedish Children
Background: Although callous-unemotional (CU) traits have been associated with bullying among children and adolescents, relatively little is known about whether each of the three sub-constructs of CU traits—callous, uncaring, and unemotional—are associated with bullying when they are considered concurrently in the analysis. Objective: This study was the first to examine in a single model whether c
Health research in the European Union : over-controlled but under-measured?
Classification of spectra of the Neumann–Poincaré operator on planar domains with corners by resonance
We study spectral properties of the Neumann–Poincaré operator on planar domains with corners with particular emphasis on existence of continuous spectrum and pure point spectrum. We show that the rate of resonance at continuous spectrum is different from that at eigenvalues, and then derive a method to distinguish continuous spectrum from eigenvalues. We perform computational experiments using the
Microsurgical Subinguinal Varicocele Repair of Grade II-III Lesions Associated with Improvements of Testosterone Levels
Introduction: The results of reports on the association between varicocele repair and testosterone levels were conflicting. The aim of the present study is, therefore, to investigate the impact of varicocele repair on testosterone levels. Materials and Methods: The study is based on 20 men who experienced microsurgical subinguinal varicoceles repair because of chronic dull scrotal pain. All hormon
Hypoxia, pseudohypoxia and cellular differentiation
Tumor hypoxia correlates to aggressive disease, and while this is explained by a variety of factors, one clue to understand this phenomena was the finding that hypoxia induces a de-differentiated, stem cell-like phenotype in neuroblastoma and breast tumor cells. The hypoxia inducible transcription factors (HIFs) are regulated at the translational level by fluctuating oxygen concentrations, but eme
Distribution of CGRP and its receptor components CLR and RAMP1 in the rat retina
Calcitonin gene-related peptide (CGRP) is a 37 amino acid neuropeptide with several functions including vasodilation, the perception of painful stimuli, and inflammation. The CGRP receptor consists of two main components; calcitonin-like receptor (CLR) and receptor activity-modifying protein 1 (RAMP1). While there is a growing recognition that CGRP plays a key role in migraine, the function of CGR
Routine coagulation tests on ICU admission are associated with mortality in sepsis : an observational study
Background: Low platelet count on admission to an intensive care unit (ICU) is associated with increased mortality and is thus included in some severity scoring systems such as the simplified acute physiologic score 3 (SAPS 3); however it is unclear whether other routine coagulation tests also predict mortality. The purpose of this retrospective single-centre study was to investigate whether activ
Preventing Malaria among Under Five Children in Damot Gale Woreda, Wolayta Zone, Ethiopia: The Role of Parents Knowledge and Treatment Seeking
Background: Malaria is the leading public health problem in Ethiopia. Lack of malaria-specific knowledge has been commonly assumed to be an important barrier to engagement in behaviors that prevent malaria and prompt health seeking behavior. Objective: To assess parents’ knowledge, practice of prevention, treatment seeking and factors associated with malaria prevention among under-five children in
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The necessity of exploring the transformation of anger in psychotherapy is highlighted in scientific literature. Such analysis could deepen our understanding of destructive and constructive possibilities of anger expression. The aim of this research was to reveal subjectively important changes of anger expression and therapeutic factors. Female clients, who had accomplished their long-term therapy
Serier vi inte minns : Skräckserier för tjejer
Anteckningar till en föreläsning hållen för Seriefrämjandet Skåne på Rum för serier, Malmö. En presentation av tre serietidningar från den ofta förbisedda genren skräckserier för tjejer: brittiska Spellbound och Misty från 1970-talet och tyska Vanessa - Freundin der Geister från 1980-talet. Bilder ej inkluderade upphovsrättsliga skäl.Lecture notes from a lecture held for the Swedish Comics Association, Scanian Branch at Rum för serier, Malmö. A presentation of three comic books representing the often overlooked genre of horror comics for girls: the British Spellbound and Misty, both from the 1970s, and the German Vanessa - Freundin der Geister, from the 1980s. Images not included for copyright reasons.
Experimental and numerical assessment of the work of fracture in injection-moulded low-density polyethylene
The fracture mechanics properties of injection-moulded low-density polyethylene (LDPE) sheets were investigated both experimentally and numerically. The total work of fracture was determined experimentally, by means of fracture mechanics testing of sheets of injection-moulded LDPE with side cracks of different lengths. A multi-specimen method, proposed by Kim and Joe (1987), was employed. The tota
Experimenting with a circular business model: Lessons from eight cases
Experimentation is an important capability in the transition to a sustainable business. The aim of business experimentation is to learn and improve business model innovation activities with limited risks and resources through continuous and collective learning with stakeholders. Through action research we worked with eight case companies on a pathway to becoming a sustainable business. We focused
Point of no return for improvement of cartilage quality indicated by dGEMRIC before and after weight loss in patients with knee osteoarthritis : a cohort study
Background: It has been demonstrated that weight loss improves symptoms in obese subjects with knee osteoarthritis (KOA). A parallel change in cartilage morphology remains to be demonstrated. Purpose: To demonstrate a parallel change in cartilage morphology. Material and Methods: Obese patients with KOA were examined before and after weight loss over 16 weeks. Target knee joints were radiographica