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Media Experiences : Engaging with Drama and Reality Television

Media Experiences travels across people and popular culture, exploring the pathways to engagement and the various ways in which we shape and are shaped by the media landscapes in which we move. This exploration includes the voices and bodies, sights and sounds of audiences as they experience entertainment through television drama, reality TV, at live events, and within digital television itself, a

Where are the storytellers? : A quest to (re)enchant geography through writing as method

The standardization of writing styles and formats and the use of jargon in the social sciences have had considerable consequences on the quality of academic work. Due to the emphasis on method, theory, and empirical rigor, creativity, personal narrative, and storytelling no longer play a large role in academic writing. Addressing the growing concern for researchers losing their sense of self, the

Obstructive sleep apnea and self-reported functional impairment in revascularized patients with coronary artery disease in the RICCADSA trial

Purpose: Daytime sleepiness, a frequent symptom of obstructive sleep apnea (OSA), can impact functional status. In patients with coronary artery disease (CAD) and concomitant OSA, the distinction between sleep-related functional impairment from underlying CAD versus OSA is unclear. This study evaluated the impact of OSA on sleep-related functional impairment in patients with CAD and compared the e

Epidemiology of subdural haemorrhage during infancy : A population-based register study

OBJECTIVES: To analyse subdural haemorrhage (SDH) during infancy in Sweden by incidence, SDH category, diagnostic distribution, age, co-morbidity, mortality, and maternal and perinatal risk factors; and its association with accidents and diagnosis of abuse.METHODS: A Swedish population-based register study comprising infants born between 1997 and 2014, 0-1 years of age, diagnosed with SDH-diagnose

Wild African Drosophila melanogaster are seasonal specialists on marula fruits

Although the vinegar fly Drosophila melanogaster isarguably the most studied organism on the planet,fundamental aspects of this species’ natural ecologyhave remained enigmatic [1]. We have here investigateda wild population of D. melanogaster from amopane forest in Zimbabwe. We find that these fliesare closely associated with marula fruit (Sclerocaryabirrea) and propose that this seasonally abunda

Combining Graphical Descriptions and Equations for Dynamical Modelling

The modelling of large systems is greatly simplified if their hierarchical decomposition and interconnection structure can be described graphically. The paper describes a system allowing input of block diagrams and continuous zooming to view internal details. Model equations are automatically transformed to assignment statements when possible, allowing efficient explicit integration routines to be

Hypothalamic–pituitary and growth disorders in survivors of childhood cancer : An endocrine society* clinical practice guideline

Objective: To formulate clinical practice guidelines for the endocrine treatment of hypothalamic–pituitary and growth disorders in survivors of childhood cancer. Participants: An Endocrine Society–appointed guideline writing committee of six medical experts and a methodologist. Conclusions: Due to remarkable improvements in childhood cancer treatment and supportive care during the past several dec

Initial intraocular pressure reduction by mono- versus multi-therapy in patients with open-angle glaucoma : results from the Glaucoma Intensive Treatment Study

PURPOSE: To study newly diagnosed glaucoma patients given mono- or multi-therapy regarding differences in initial intraocular pressure (IOP) reduction, target IOP levels reached and influence of untreated baseline IOP on IOP reduction.METHODS: Patients newly diagnosed with manifest primary open-angle glaucoma and included in the Glaucoma Intensive Treatment Study (GITS) were randomized to immediat

The digestive machinery of a human gut bacterium : Structural enzymology of galactomannan utilisation

Vi kryllar av bakterier. De bor framför allt i vår tjocktarm där de lever på de delar av vår mat som vi inte kan ta hand om själva. I utbyte omvandlar bakterierna en del av maten de äter till vitaminer och fettsyror som är viktiga för oss. Det bor flera olika arter av bakterier i vår tarm som äter lite olika saker, eftersom det är ont om mat för så många har de flesta specialiserat sig för att minHuman gut bacteria utilise different types of polysaccharides present in our diet. One of these polysaccharides is galactomannan. Many organisms in the phylum Bacteroidetes have gene clusters encoding for all proteins required for hydrolysis, binding and transport of one type of polysaccharide, called polysaccharide utilisation loci (PULs). A PUL from the human gut bacterium Bacteroides ovatus was

Pan-cancer analysis of neoepitopes

Somatic variations are frequent and important drivers in cancers. Amino acid substitutions can yield neoantigens that are detected by the immune system. Neoantigens can lead to immune response and tumor rejection. Although neoantigen load and occurrence have been widely studied, a detailed pan-cancer analysis of the occurrence and characterization of neoepitopes is missing. We investigated the pro

Protein stabilization with retained function of monellin using a split GFP system

Sweet proteins are an unexploited resource in the search for non-carbohydrate sweeteners mainly due to their low stability towards heating. Variants of the sweet protein monellin, with increased stability, were derived by an in vivo screening method based on the thermodynamic linkage between fragment complementation and protein stability. This approach depends on the correlation between mutational

Pickering emulsifiers based on hydrophobically modified small granular starches Part II – Effects of modification on emulsifying capacity

Small granular starches from rice, quinoa, and amaranth were modified with octenyl succinic anhydride (OSA) at 5 defined intervals (0–3.0%) and investigated with respect to emulsifying capacity and stability. Starch granule surfaces were characterized by Brunauer–Emmett–Teller and contact angle measurements. Emulsifying capacity was characterized by multiple light scattering (MLS) and particle siz

Three-year recurrence of Dupuytren’s contracture after needle fasciotomy and collagenase injection : a two-centre randomized controlled trial

Collagenase injection and needle fasciotomy have similar short-term outcomes in the treatment of Dupuytren’s contracture. The purpose of this study was to compare the recurrence rate of these two procedures 3 years after index treatment of primary disease. We enrolled 93 patients (96 rays) from a previous two-centre randomized controlled trial. The rays that had been retreated or showed an increas

An early post-operative ACTH suppression test can safely predict short- and long-term remission after surgery of Cushing’s disease

Purpose: The present study evaluates the usefulness of an ACTH suppression test shortly after surgery, and to determine optimal cut-off values of included laboratory analyses, in predicting short- and long-term remission after surgery of Cushing’s disease. Methods: A 48 h suppression test with betamethasone 2 mg/day applied after 45 transphenoidal adenomectomies in 28 patients was evaluated. Recei

Transformation from crystalline precursor to perovskite in PbCl2-derived MAPbI3

Understanding the formation chemistry of metal halide perovskites is key to optimizing processing conditions and realizing enhanced optoelectronic properties. Here, we reveal the structure of the crystalline precursor in the formation of methylammonium lead iodide (MAPbI3) from the single-step deposition of lead chloride and three equivalents of methylammonium iodide (PbCl2 + 3MAI) (MA = CH3NH3).

War and well-being in transition: Evidence from two natural experiments

This paper assesses the effect of the Russo–Georgian conflict of 2008 and the Ukrainian–Russian conflict of 2014 on the well-being of minorities in Russia. Using the Russian Longitudinal Monitoring Survey (RLMS), we find that the well-being of Georgians in Russia suffered negatively from the 2008 Russo–Georgian conflict. We show that the conflict has no direct effect on the labor market outcomes o