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Measurements of inclusive and differential fiducial cross-sections of tt¯ γ production in leptonic final states at √s=13TeV in ATLAS
Inclusive and differential cross-sections for the production of a top-quark pair in association with a photon are measured with proton-proton collision data corresponding to an integrated luminosity of 36.1 fb-1, collected by the ATLAS detector at the LHC in 2015 and 2016 at a centre-of-mass energy of 13 TeV. The measurements are performed in single-lepton and dilepton final states in a fiducial v
Dally-like protein, a new Drosophila glypican with expression overlapping with wingless
Proteoglycans, the molecules of extracellular matrix, carry a highly negative charge due to their glycosaminoglycan (GAG) chains and large volumes. They were considered to play a secondary role in activities like cell division, adhesion, blood coagulation, etc. until the importance of their sugar chains in the fibroblast growth factor (FGF) signalling was discovered (Science 252 (1991) 1705; Cell
wing blister, A new Drosophila laminin alpha chain required for cell adhesion and migration during embryonic and imaginal development
We report the molecular and functional characterization of a new α chain of laminin in Drosophila. The new laminin chain appears to be the Drosophila counterpart of both vertebrate α2 (also called merosin) and α1 chains, with a slightly higher degree of homology to α2, suggesting that this chain is an ancestral version of both αl and α2 chains. During embryogenesis, the protein is associated with
Splice variants of the Drosophila PS2 integrins differentially interact with RGD-containing fragments of the extracellular proteins tiggrin, Ten-m, and D-laminin α2
Two new potential ligands of the Drosophila PS2 integrins have been characterized by functional interaction in cell culture. These potential ligands are a new Drosophila laminin α2 chain encoded by the wing blister locus and Ten-m, an extracellular protein known to be involved in embryonic pattern formation. As with previously identified PS2 ligands, both contain RGD sequences, and RGD-containing
A Drosophila neurexin is required for septate junction and blood-nerve barrier formation and function
Septate and tight junctions are thought to seal neighboring cells together and to function as barriers between epithelial cells. We have characterized a novel member of the neurexin family, Neurexin IV (NRX), which is localized to septate junctions (SJs) of epithelial and glial cells. NRX is a transmembrane protein with a cytoplasmic domain homologous to glycophorin C, a protein required for ancho
Letters to the Editors
The Polycomb-group gene, extra sex combs, encodes a nuclear member of the WD-40 repeat family
We have delimited the extra sex combs (esc) gene to
The HEM Proteins : A novel family of tissue-specific transmembrane proteins expressed from invertebrates through mammals with an essential function in oogenesis
We report the identification of a new family of proteins, termed the HEM family, which show distinct expression patterns in blood cells and the central nervous system. Through the isolation and characterization of the corresponding brain-specificDrosophila(dhem-2) and rat orthologues (Hem-2), and through the detection of theCaenorhabditis elegansHem-2 orthologue in the database, we show that this
tenm, a Drosophila gene related to tenascin, is a new pair-rule gene
We describe the molecular characterization of the Drosophila gene tenm, a large transcription unit spanning > 110 kb of DNA. tenm encodes a large extracellular protein of 2515 amino acids related to the extracellular matrix molecule tenascin. The Tenm protein is found in seven stripes during the blastoderm stage, and each stripe overlaps with the even-skipped stripes. tenm mutants show a phenotype
Comparing Non-projective Strategies for Labeled Graph-Based Dependency Parsing
The 55 kd regulatory subunit of Drosophila protein phosphatase 2A is required for anaphase
The gene encoding the Drosophila protein phosphatase 2A 55 kd regulatory subunit (PR55) is located at 85F and directs the synthesis of differentially spliced transcripts. Maternal RNAs are present at very high levels in early embryos and decline around cellularization. Zygotic transcripts are present mainly in the developing embryonic nervous system and gonads. Transcripts are uniformly distribute
Tena, a Drosophila gene related to tenascin, shows selective transcript localization
We report the identification and molecular characterization of tena*, a Drosophila gene located at 11A6-9 on the X-chromosome. The deduced protein of 782 amino acids contains eight tenascin-type EGF-like repeats not described in Drosophila before, but lacks the fibronectin type III repeats and the fibrinogen homology present in the vertebrate tenascin molecules. Tena codes for a large transcript w
Phrase Structures and Dependencies for End-to-End Coreference Resolution
Drosophila ribosomal protein S19 cDNA sequence
Elevated plasma copeptin levels identify the presence and severity of non-alcoholic fatty liver disease in obesity
Introduction: Copeptin is the stable surrogate marker of vasopressin (VP), which is released in response to elevated plasma osmolality or low blood pressure. Elevated plasma copeptin levels are associated with higher risk of insulin resistance-related disorders, such as type 2 diabetes (T2DM), metabolic syndrome (MS), and cardiovascular disease, and experimental reduction of circulating VP levels
Essays on Urban Economics
AbstractBlind, I. 2015. Essays on Urban Economics. Economic studies 153. xii+199 pp. Uppsala:Department of Economics. ISBN 978-91-85519-60-6.This thesis consists of four self-contained essays.Essay 1 (with Olof Åslund and Matz Dahlberg): In this essay we investigate the impact ofcommuter train access on individual labor market outcomes. Our study considers the exogenousintroduction of a commuter t
Molecular cloning and developmental expression of the catalytic and 65-kDa regulatory subunits of protein phosphatase 2A in Drosophila
cDNA clones encoding the catalytic subunit and the 65-kDa regulatory subunit of protein phosphatase 2A (PR65) from Drosophila melanogaster have been isolated by homology screening with the corresponding human cDNAs. The Drosophila clones were used to analyze the spatial and temporal expression of the transcripts encoding these two proteins. The Drosophila PR65 cDNA clones contained an open reading
Network of interactions among pair-rule genes regulating paired expression during primordial segmentation of Drosophila
A model of the trans-regulation of the Drosophila pair-rule segmentation gene, paired (prd), has been derived from the observed alterations in the distribution of prd transcripts during early embryogenesis in single and double pair-rule mutants. Important aspects of the model include the following features and implications: (i) The regulation of prd is subject to a regulatory hierarchy among pair-
Isolation of two tissue-specific Drosophila paired box genes, Pox meso and Pox neuro
Two new paired domain genes of Drosophila, Pox meso and Pox neuro, are described. In contrast to the previously isolated paired domain gnees, paired and gooseberry, which contain both a paired and a homeodomain (PHox genes), Pox meso and Pox neuro possess no homeodomain. Evidence suggesting that the new genes encode tissue-specific transcriptional factors and belong to the same regulatory cascade