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Hydrolysis of phosphatidylethanolamine by human pancreatic phospholipase A2. Effect of bile salts.

The 2-ester bond of 14C-2-arachidonyl phosphatidylethanolamine (PE) was hydrolyzed faster than that of 3H-2-arachidonyl phosphatidylcholine (PC) by human pancreatic phospholipase A2 (PLA2) with mixed PE-PC (1:9 w/w) liposomes of pure sonicated PE or PC as substrate. The PC portion of the mixed PE-PC liposomes was more readily attacked by PLA2 than the PC of pure PC liposomes. At different bile sal

Systematiskt säkerhetsarbete och beslutsfattande : - att förstå, förklara och förbättra

Sekuritet eller den säkerhet i samma betydelse som engelskans security, handlar om det verksamhetsskydd för organisation, medarbetare och övriga som behövs för att motverka fara, skada, förlust eller brott. Sekuritet är därmed en fråga om trygghet. För att möta framtidens utmaningar har doktorandarbetet syftat till att studera och identifiera effektiva processer gällande sekuritetshantering och be

Linking damping of electromechanical oscillations to system operating conditions using neural networks

This paper presents the application of Neural Networks to link the damping of electromechanical oscillations in the Nordic power system to the measured operating conditions. Different neural network topologies have already been presented in the literature for this application, but using exclusively data from simulations. The primary objective of the paper is to analyze how these topologies behave

Hydrolysis of phosphatidylinositol by human panreatic phospholipase A2

Pure human pancreatic phospholipase A2 efficiently hydrolyzed the 2-ester bond of 14C-2-linoleoyl and 14C-2-arachidonyl phosphatidylinositol (PI). The rate of hydrolysis varied markedly with the bile salt (sodium taurocholate to sodium taurodeoxycholate, 3:4 mol/mol) concentration, the hydrolysis being decreased with increasing bile salt to PI ratio. The influence of bile salts was thus similar to