Methodological tools for studies of the cytostatic agen cisplatin (CDDP) were explored and applied to elucidate various aspects of pharmacokinetics, drug distribution, chemomodulation and pharmacodynamics. An immunohistochemical assay for analysis of CDDP-DNA adducts, i.e. the drug in its probable target position, was modified to allow quantitation with computerized image analysis. The methodologi

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Abstract in UndeterminedPosttraumatic Stress Disorder (PTSD) is the one of the most common reactions arising in the aftermath of traumatic events. PTSD is characterised by frequent and intrusive recollections of the event, emotional restriction and avoidance, and hyper arousal. Many clients also develop dysfunctional beliefs about their own PTSD symptoms, which in turn cause increased levels of im

The book consists of nine chapters which address three major topics: current issues in biblical scholarship, various aspects of love and death, and also theology of religions. It is a sequel to the previous book "Skriftens ansikten: Konsten att läsa mellan raderna".

The traditional routing protocols used in wireless mesh networks like AODV are not very efficient since the number of hops to a destination is mainly considered as the routing metric. This may lead to shorter paths; however, the throughput can decrease when traffic is routed through those paths. Various contributions have proposed different metrics or completely different routing algorithms. Never

Fifty-one teenage cases with anorexia nervosa (AN) were compared with 51 age-, sex-, and school-matched cases with respect to premorbid developmental, physical, and psychiatric problems and comorbidity at the time of examination. Almost half of the AN group consisted of the total population of AN cases in one birth cohort. There were more premorbid personality problems in the AN group. Obsessive c

Popular Abstract in Swedish Förståelse av väldigt snabba proceeser i molekyler utgör grunden inom modern kemi. Jonisation och excitation av en molekyl med en foton startar en nukleär dynamisk process som åtföljs av elektroniskt sönderfall och fragmentering av molekylen. En rörelsemändsvektor-spektrometer har utveclats som används för att mäta massa, laddning, energi och hastighet av joniska fragmeA momentum imaging spectrometer optimized for photoionization experiments with synchrotron radiation was built in 2008. The spectrometer is equipped with an electrostatic lens, that focuses the charged dissociation products on to a position-sensitive multi-hit delay line anode. The possibility of focusing is essential for most applications, where fragment momentum is to be extracted. The apparatus

The design of an ultra-low-leakage latch, suitable for subthreshold standard-cell based memories in 65nm CMOS is presented. Various latch architectures are compared in terms of leakage, area and speed. The most leakage-efficient architecture is optimized by transistor stacking and channel length stretching. The final design is supplemented with a 3-state output buffer to provide low-leakage read f