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Hypothermia is shown to be beneficial for the outcome after a transient global brain ischaemia through its neuroprotective effect. Whether this is also the case after focal ischaemia, such as following a severe traumatic brain injury (TBI), has been investigated in numerous studies, some of which have shown a tendency towards an improved outcome, whereas others have not been able to demonstrate an
Heritable epigenetic signatures are proposed to serve as an important regulatory mechanism in lineage fate determination. To investigate this, we profiled chromatin modifications in murine hematopoietic stem cells, lineage restricted progenitors and CD4(+) T cells using modified genome-scale miniChIP technology. We show that genes involved in mature hematopoietic cell function associate with disti
Introduction: Rivaroxaban is an oral direct factor Xa inhibitor developed for prophylaxis and treatment of thromboembolic disorders. Laboratory monitoring is not necessary but the dose dependent effects on common reagents and assay procedures are largely unknown. Objectives: To investigate the effect of rivaroxaban on commonly used coagulation assays. Material and Methods: Rivaroxaban was added to
Glycoprotein 340 (gp-340) is a bacterial-binding glycoprotein found in major-gland and minor-gland saliva. Sialic acid, a common terminal structure of salivary glycoproteins, interacts with microorganisms and host ligands, as well as with free radicals. This study investigated the contents of gp-340 and sialic acid in minor-gland saliva and whole saliva of children (3 yr of age), adolescents (14 y
The incidences of both type 1 diabetes (T1D) and T2D are increasing worldwide. T2D is associated with many cancers. However, no data are available on cancer of unknown primary (CUP), a relatively common, fatal cancer for which tobacco smoking is the only known risk factor. At diagnosis, CUP metastases are found in various organs, which has implications for prognosis. We carried out a nationwide st
More than 50 years ago, Fish postulated that a special form of early abnormal neurodevelopment, "pandysmaturation", defined a priori as constituting retarded cranial development in the first year of life, combined with delay in early motor milestone attainment, was related to genetic risk for schizophrenia, and was associated with schizophrenia-spectrum disorders in young adulthood. Fish confirmed
This work presents an overview of four different approaches to the problem of future contingency and determinism in temporal logics. All of them are bivalent, viz. they share the assumption that propositions concerning future contingent facts have a determinate truth-value (true or false). We introduce Ockhamism, Peirceanism, Actualism and T x W semantics, the four most relevant bivalent alternati
The paper describes a concept for securing the geometry in flexible production based on robot assisted framing. This uses the robot(s) as an active device during change-over between product variants and it is assumed that product variants can be produced in any mixed order. The case under study is cabs for trucks which in traditional production require large and heavy equipment which is above the
The European research project ‘Experiences of Children from Rainbow Families in School’ (2009 – 2011) conducted by researchers from Humboldt-Universität zu Berlin, Germany (Centre for Transdisciplinary Genderstudies), University Ljubljana, Slovenia (Department of Social Justice and Inclusions, Faculty of Social Work) and Lund University, Sweden (Centre for Gender Studies) focuses in its comparativ
