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Between Religious Studies, Religious Education, Teaching Education, and Religion and Education : Relationships, Opportunities, Tensions

The aim of the present paper is to explore the interrelated and complex relationships between religionsvetenskap (Religious Studies), religionskunskap (Religious Education) and religionsdidaktik (Religion and Education). After briefly outlining the concurrent developments of Religious Studies as a university discipline and Religion and Eudcation as a non-confessional school subject, both of which

Obsessive-Compulsive Disorder : Diagnosis, Clinical Features, Nosology, and Epidemiology

Key points• Obsessive-compulsive disorder is a disabling mental disorder with a lifetime prevalence of around 2% with similar rates across age groups and countries.• Diagnosis is made based on a pattern of time-consuming, clinically distressing, or impairing obsessions and compulsions and most cases emerge during puberty or early adulthood.• Obsessions are recurrent, persistent, and intrusive thou

English dictionaries, gold and silver standard corpora for biomedical natural language processing related to SARS-CoV-2 and COVID-19

Here we present a toolbox for natural language processing tasks related to SARS-CoV-2. It comprises English dictionaries of synonyms for SARS-CoV-2 and COVID-19, a silver standard corpus generated with the dictionaries and a gold standard corpus of 10 Pubmed abstracts manually annotated for disease, virus, symptom and protein/gene terms. This toolbox is freely available on github and can be used f

In Situ Observation of C−C Coupling and Step Poisoning During the Growth of Hydrocarbon Chains on Ni(111)

The synthesis of high-value fuels and plastics starting from small hydrocarbon molecules plays a central role in the current transition towards renewable energy. However, the detailed mechanisms driving the growth of hydrocarbon chains remain to a large extent unknown. Here we investigated the formation of hydrocarbon chains resulting from acetylene polymerization on a Ni(111) model catalyst surfa

Points to patches: Enabling the use of self-attention for 3D shape recognition

While the Transformer architecture has become ubiquitous in the machine learning field, its adaptation to 3D shape recognition is non-trivial. Due to its quadratic computational complexity, the self-attention operator quickly becomes inefficient as the set of input points grows larger. Furthermore, we find that the attention mechanism struggles to find useful connections between individual points

A new generation of thermal energy benchmarks for university buildings

In 2008, the Chartered Institution of Building Services Engineers (CIBSE TM46 UC) presented an annual-fixed thermal energy benchmark of 240 kWh/m2/yr for university campus (UC) buildings as an attempt to reduce energy consumption in public buildings. However, the CIBSE TM46 UC benchmark fails to consider the difference between energy demand in warm and cold months, as the thermal performance of bu

Impact of the COVID-19 pandemic on the energy performance of residential neighborhoods and their occupancy behavior

Several contrasting effects are reported in the existing literature concerning the impact assessment of the COVID-19 outbreak on the use of energy in buildings. Following an in-depth literature review, we here propose a GIS-based approach, based on pre-pandemic, partial, and full lockdown scenarios, using a bottom-up engineering model to quantify these impacts. The model has been verified against

Challenges and opportunities for regenerating lung tissue using three-dimensional lung models

Lung transplantation is currently the only option for patients with end-stage respiratory diseases, but owing to various complications and adverse effects of the treatment in combination with the increasing demand for and limited access to donor organs, new strategies are needed. Recent advances in materials science, culture techniques, cell-phenotyping and isolation techniques, bioreactor enginee

Model visualization : from micro to macro

Because of increasing demand, rapid development of in vitro and in vivo models to be used to study lung regeneration and lung repair has occurred during the last years. Even if imaging has always been an important tool in diagnosing disease and validating models, the current disease models, including three-dimensional (3D) lung models, put a higher demand on advanced imaging techniques. Moreover,

Mesenchymal stromal cells-derived extracellular vesicles repsogramme macrophages in ARDS models through the miR-181a-5p-PTEN-psTAT5-SOCS1 axis

Rationale A better understanding of the mechanism of action of mesenchymal stromal cells (MSCs) and their extracellular vesicles (EVs) is needed to support their use as novel therapies for acute respiratory distress syndrome (ARDS). Macrophages are important mediators of ARDS inflammatory response. Suppressor of cytokine signalling (SOCS) proteins are key regulators of the macrophage phenotype swi

Comparative immunogenicity of decellularized wild type and alpha 1,3 galactosyltransferase knockout pig lungs

Decellularized pig lungs recellularized with human lung cells offer a novel approach for organ transplantation. However, the potential immunogenicity of decellularized pig lungs following exposure to human tissues has not been assessed. We found that exposure of native lungs from wildtype and transgenic pigs lacking alpha (1,3)-galactosyltransferase (α-gal KO) to sera from normal healthy human vol

MSCs interaction with the host lung microenvironment : An overlooked aspect?

Mesenchymal stromal cells (MSCs) were identified more than 50 years ago, and research advances have promoted the translation of pre-clinical studies into clinical settings in several diseases. However, we are only starting to uncover the local factors that regulate cell phenotype, cell function, and cell viability across tissues following administration in different diseases. Advances in pre-clini

Mesenchymal stem/stromal cell-based therapies for severe viral pneumonia: therapeutic potential and challenges

Severe viral pneumonia is a significant cause of morbidity and mortality globally, whether due to outbreaks of endemic viruses, periodic viral epidemics, or the rarer but devastating global viral pandemics. While limited anti-viral therapies exist, there is a paucity of direct therapies to directly attenuate viral pneumonia-induced lung injury, and management therefore remains largely supportive.

Local municipalities and the influence of national networks on city climate governance : Small places with big possibilities

Reaching the 1.5°C target of the Paris Agreement not only requires ambitious goals from national governments, but also the active participation of local municipalities. It is in cities where climate actions need to be implemented to reduce greenhouse gas emissions and reach international and national climate goals. While the importance of cities and their participation in networks has been well-re

Indirect effect of alpha-1-antitrypsin on endotoxin-induced IL-1β secretion from human PBMCs

Human alpha-1-antitrypsin (AAT) encoded by the SERPINA1 gene, is an acute phase glycoprotein that regulates inflammatory responses via both protease inhibitory and non-inhibitory activities. We previously reported that AAT controls ATP-induced IL-1β release from human mononuclear cells by stimulating the release of small bioactive molecules. In the current study, we aimed to elucidate the identity

Atmospherically Relevant Chemistry and Aerosol box model - ARCA box (version 1.2)

We introduce the Atmospherically Relevant Chemistry and Aerosol box model ARCA box (v.1.2.2). It is a zero-dimensional process model with a focus on atmospheric chemistry and submicron aerosol processes, including cluster formation. A novel feature in the model is its comprehensive graphical user interface, allowing for detailed configuration and documentation of the simulation settings, flexible

Dry season forage assessment across senegalese rangelands using earth observation data

Strengthening of feed security in the Sahel is urgently needed given the climate change and growing human population. A prerequisite to this is sustainable use of rangeland forage resources for livestock. Many studies have focused on the assessment of rangeland resources during the rainy season, while only a few have focused on the dry season which is the longest and most demanding period for live

The evolution of predator avoidance in cephalopods : A case of brain over brawn?

Predation is a major evolutionary driver of animal adaptation. However, understanding of anti-predator evolution is biased toward vertebrate taxa. Cephalopoda, a class in the invertebrate phylum Mollusca, are known for their diverse anti-predator strategies, characterised by their behavioural flexibility. While ancestral cephalopods were protected by a hard outer shell, extant cephalopods have gre