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Damped transient response of the giant dipole resonance in the lead region

We analyze thoroughly the statistical properties of the 1- spectrum in energy interval 9.5-18.5 MeV for Hg206, Pb204,206,208, and Po210 nuclei. To this aim we use the Skyrme interaction SLy4 and the volume pairing interaction, treated in the BCS approximation, as our model Hamiltonian to create a single-particle spectrum and to analyze excited states. The excited states are obtained in the quasipa

Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis

Non-coding RNAs regulate many biological processes including neurogenesis. The brain-enriched miR-124 has been assigned as a key player of neuronal differentiation via its complex but little understood regulation of thousands of annotated targets. To systematically chart its regulatory functions, we used CRISPR/Cas9 gene editing to disrupt all six miR-124 alleles in human induced pluripotent stem

Methane and global environmental change

Global atmospheric methane concentrations have continued to rise in recent years, having already more than doubled since the Industrial Revolution. Further environmental change, especially climate change, in the twenty-first century has the potential to radically alter global methane fluxes. Importantly, changes in temperature, precipitation, and net primary production may induce positive climate

Associations of Circulating Protein Levels With Lipid Fractions in the General Population

Objective- Revealing patterns of associations between circulating protein and lipid levels could improve biological understanding of cardiovascular disease (CVD). In this study, we investigated the associations between proteins related to CVD and triglyceride (TG), total cholesterol, LDL (low-density lipoprotein), and HDL (high-density lipoprotein) cholesterol levels in individuals from the genera

Social inequality in working life expectancy in Sweden

BACKGROUND: In Sweden there is a socioeconomic divide between white and blue collar workers with respect to the risk for premature exit from working life. Disability pension has long represented a major reason behind early exits.OBJECTIVE: The present investigation aimed at studying the effect on socioeconomic groups of new guidelines issued by the Swedish government in 2006, limiting the possibil

Tumor stiffness extends its grip on the metastatic microenvironment

The increased stiffness of a tumor triggers a multitude of responses that aid cancer cell dissemination. Stiffness-induced expression of CCN1 mediates autocrine signaling in the endothelium to upregulate N-Cadherin levels. This permits more stable interactions with cancer cells and increases their ability to spread into the circulation.

A new way of monitoring mechanical ventilation by measurement of particle flow from the airways using Pexa method in vivo and during ex vivo lung perfusion in DCD lung transplantation

BACKGROUND: Different mechanical ventilation settings are known to affect lung preservation for lung transplantation. Measurement of particle flow in exhaled air may allow online assessment of the impact of ventilation before changes in the tissue can be observed. We hypothesized that by analyzing the particle flow, we could understand the impact of different ventilation parameters.METHODS: Partic

Similarity in Fog and Rainfall Intermittency

Intermittent fog occurrences supply significant amounts of moisture to plants in the form of fog drip onto the soil surface thereby prompting interest in their statistical behavior at multiple timescales. A comparison of rainfall and fog measurements collected at an inland tropical cloud forest in Kenya and a coastal rangeland in Northern California is presented to explore whether fog occurrences

Approach to combine electron-beam lithography and two-photon polymerization for enhanced nano-channels in network-based biocomputation devices

Although conventional computer technology made a huge leap forward in the past decade, a vast number of computational problems remain inaccessible due to their inherently complex nature. One solution to deal with this computational complexity is to highly parallelize computations and to explore new technologies beyond semiconductor computers. Here, we report on initial results leading to a device

Suppression of endwall heat transfer in the junction region with a symmetric airfoil by a vortex generator pair

The high endwall heat transfer in the junction of the hub and vane/blade is very crucial in turbomachinery and is of great concern for increasing the gas turbine inlet temperature but avoiding hot spots. The vortices generated in that region are mainly responsible for the high heat transfer. By controlling these vortices, heat transfer in the junction region can be controlled. In this study, a new

A critical review on the application of the National Sanitation Foundation Water Quality Index

Many studies have employed the National Sanitation Foundation Water Quality Index (NSFWQI) with non-original rather than originally defined parameters of the model, particularly when incorporating fecal coliform (FC), total solids, and total phosphates as inputs. For this reason, this study aimed to perform a critical review on the application of the NSFWQI to explore the amount of change that can

Search for resonant WZ production in the fully leptonic final state in proton–proton collisions at s=13TeV with the ATLAS detector

A search for a heavy resonance decaying into WZ in the fully leptonic channel (electrons and muons) is performed. It is based on proton–proton collision data collected by the ATLAS experiment at the Large Hadron Collider at a centre-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 36.1 fb−1. No significant excess is observed over the Standard Model predictions and limits are