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Meteorin is a chemokinetic factor in neuroblast migration and promotes stroke-induced striatal neurogenesis.

Ischemic stroke affecting the adult brain causes increased progenitor proliferation in the subventricular zone (SVZ) and generation of neuroblasts, which migrate into the damaged striatum and differentiate to mature neurons. Meteorin (METRN), a newly discovered neurotrophic factor, is highly expressed in neural progenitor cells and immature neurons during development, suggesting that it may be inv

Energy resolved electron – ion coincidence study near the S 2p thresholds of the SF6 molecule

The fragmentation dynamics of the SF6 molecule following the excitations of S 2p electrons into unoccupied molecular orbitals has been studied using the energy-resolved electron–ion coincidence technique. Fragmentation patterns were found to depend on the particular excitation and on the electronic state of the molecular ion. The spectator resonant Auger decay at the 2p → 6a1g resonance induces ch

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"I'm Inca": The Fiesta of Mamacha Carmen in the Andean Village of Pisac

This article examines the communication of identity in ritual dancing during the Fiesta de Virgen del Carmen in Pisac, a village in the Peruvian Andes. In framing an arena for representation and interpreting local lifeworlds the fiesta is endowed with profoundly existential significance for the participants. In performing the different characters, the dancers are given opportunities to renegotiate

Polymorphisms, haplotypes and mutations in the protamine 1 and 2 genes.

Protamines are the most abundant nuclear proteins and alterations in their expression have been described in infertile patients. Also, protamine haplo-insufficient mice have been described as infertile. Therefore, the protamine 1 and 2 genes have been considered important candidates in different mutational studies. In this article, we review all published articles related to protamine gene mutatio

A web-based supportive intervention for families living with depression : Content analysis and formative evaluation

Background: Relatives of people with a mental illness who live together can experience additional burdens that may require support. A Web-based tool including a psychoeducation module, a diary, and a password-protected forum was developed to support relatives of a person with depression. Objective: The objective of our study was to explore participants' use of the Web-based tool, with focus on the

ABC om - Chock på akuten.

Early recognition and management of shock decreases morbidity and mortality. The recognition of chock and identification of its causes is based on an integration of the clinical context, physical findings, history and bedside tests. Ultrasound plays an important role in elucidating the cause of chock in the emergency department (ED). This article presents a systematic approach to the patient prese

A Novel Non-Synonymous Polymorphism (p.Arg240His) in C4b-Binding Protein Is Associated with Atypical Hemolytic Uremic Syndrome and Leads to Impaired Alternative Pathway Cofactor Activity.

Atypical hemolytic uremic syndrome (aHUS) is a disorder characterized by hemolytic anemia, thrombocytopenia, and acute renal failure. Mutations, polymorphisms, and copy number variation in complement factors and inhibitors are associated with aHUS. In this study, we report the first functional non-synonymous polymorphism in the complement inhibitor C4b-binding protein (C4BP) alpha-chain (c.719G>A;

Cancer Risk in Children and Young Adults Conceived by In Vitro Fertilization.

Objectives: Studies conducted so far have found no statistically significant increased risk for cancer among children who are born after in vitro fertilization (IVF). Methods: We followed 26692 children who were born after IVF during the years 1982-2005 by using the Swedish Cancer Register and compared the number of children who had cancer and were born after IVF with children who were not conceiv

Health care quality indicators on the management of rheumatoid arthritis and osteoarthritis: a literature review.

Objective. To make an inventory of quality and content of currently available and published sets of health care quality indicators (HCQIs) for RA and OA.Methods. A systematic review was performed for documents on the development and/or a description of HCQIs for the management of patients with RA and/or OA, using the PubMed, EMBASE, Web of Science, Cochrane and CINAHL databases up to 1 December 20

The Price equation and extended inheritance

The presence of various mechanisms of non-genetic inheritance is one of the main problems for current evolutionary theory according to several critics. Sufficient empirical and conceptual reasons exist to take this claim seriously, but there is little consensus on the implications of multiple inheritance systems for evolutionary processes. Here we use the Price Equation as a starting point for a d

The effect of increased experience on complications in robotic hysterectomy for malignant and benign gynecological disease.

The study objective was to assess the effect of increased experience on complications in robotic hysterectomy for malignant and benign gynecological disease. This is a retrospective cohort study. It is a Canadian Task Force classification II-2 study conducted at the University Hospital, Sweden. The patients were 949 women planned for robotic hysterectomy for malignant (75 %) and benign (25 %) gyne

Dense genotyping of immune-related loci identifies HLA variants associated with increased risk of collagenous colitis.

Collagenous colitis (CC) is a major cause of chronic non-bloody diarrhoea, particularly in the elderly female population. The aetiology of CC is unknown, and still poor is the understanding of its pathogenesis. This possibly involves dysregulated inflammation and immune-mediated reactions in genetically predisposed individuals, but the contribution of genetic factors to CC is underinvestigated. We

Modified Ritgen's maneuver for anal sphincter injury at delivery: a randomized controlled trial.

OBJECTIVE: To investigate whether Ritgen's maneuver decreases the risk of third- to fourth-degree perineal tears compared with simple perineal support. METHODS: A total of 1,623 nulliparous women in term labor, singleton pregnancy, and cephalic presentation were randomly assigned to Ritgen's maneuver or standard care. Ritgen's maneuver denotes extracting the fetal head, using one hand to pull the