Sökresultat

Filtyp

Din sökning på "*" gav 532057 sökträffar

Physicochemical properties of a mixed alkylglucoside surfactant/water system: Phase behavior, salt effects, and microstructure surrounding a closed-loop liquid/liquid miscibility gap

Mixtures of n-decyl beta-D-gluco-pyranoside (C(10)G(1)) and n-nonyl beta-D-gluco-pyranoside (C(9)G(1)) in water were studied to determine the location of a closed-loop liquid/liquid miscibility gap. A phase diagram including the point at which the closed loop first appeared was determined, as well as the effect of salts on the location of the consolute boundaries of the loop. The microstructure su

Drosophila RhoGEF2 associates with microtubule plus ends in an EB1-dependent manner

Members of the Rho/Rac/Cdc42 superfamily of GTPases [1,2] and their upstream activators, guanine nucleotide exchange factors (GEFs) [3], have emerged as key regulators of actin and microtubule dynamics. In their GTP bound form, these proteins interact with downstream effector molecules that alter actin and microtubule behavior. During Drosophila embryogenesis, a Galpha subunit (Concertina) and a R

Growth of two peat-forming mosses in subarctic mires: species interactions and effects of simulated climate change

In patches of co-occurring species in natural plant communities, there is a finely poised balance between species in the ways in which they respond to prevailing moisture and temperature regimes. However, environmental change scenarios, in which temperature, moisture and ultraviolet-B radiation are suggested to increase, may favour one of the species. The imbalance is likely to occur at the levels

Laser spectroscopy of free molecular oxygen dispersed in wood materials

The recently introduced Gas in Scattering Media Absorption Spectroscopy (GASMAS) technique is applied to the study of various wood samples. Molecular oxygen in the pores of the strongly scattering material is detected using diode laser spectroscopy around 760 nm. Diffuse light propagation in these media is studied by time-dispersion measurements. Furthermore, anisotropy related to the fibre struct

Signalling and functional diversity within the Axl subfamily of receptor tyrosine kinases.

The related Axl, Sky and Mer receptor tyrosine kinases (RTKs) are increasingly being implicated in a host of discrete cellular responses including cell survival, proliferation, migration and phagocytosis. Furthermore, their ligands Gas6 and protein S are characteristically dependent on vitamin K for expression of their functions. The Gas6/Axl system is implicated in several types of human cancer a

Approaches to molecular imprinting based selectivity in capillary electrochromatography.

The work done during the past decade in order to adapt molecularly imprinted polymers (MIPs) to the capillary format and subsequently use these highly selective matrices for capillary electrochromatography (CEC) are reviewed in this article. MIPs are prepared utilizing a templated polymer synthesis where the template addresses the selectivity of the resulting polymer. These polymers possess bindin

Glycoconjugate Binding of Gastric and Enterohepatic Helicobacter spp.

Helicobacter pylori is able to utilize several lectin-like, protein-carbohydrate interactions for binding to mucins, cell surfaces, and extracellular matrix proteins. As determined by hemagglutination assays and binding of radiolabeled bacteria to glycosphingolipids on thin-layer chromatograms, strains of gastric helicobacters and enterohepatic helicobacters, including Helicobacter canis, Helicoba

A path cover technique for LCAs in dags

As a second major result we show how to combine the path cover technique with LCA solutions for dags with small depth [9]. Our algorithm attains the best known upper time bound for this problem of O(n 2.575). However, most notably, the algorithm performs better on a vast amount of input dags, i.e. dags that do not have an almost linear-sized subdag of extremely regular structure. Finally, we appl

Effects of beach cast cleaning on beach quality, microbial food web, and littoral macrofaunal biodiversity

At the end of the summer, drifting filamentous red algae cover shallow bottoms and accumulate in huge cast walls on the open shores of the non-tidal central Baltic Sea. The hypotheses that beach cleaning increases water clarity, decreases the organic content of the sand, and increases the species diversity in the shallow zone closest to the shore, were tested through field investigations and exper

Antral G-cell in gastrin and gastrin-cholecystokinin knockout animals

The antral hormone gastrin is the key regulator of gastric acid secretion, mucosal growth and differentiation. Gastrin is synthesized in the endocrine G-cells in the antroduodenal mucosa. We have now examined the way in which the loss of gastrin alone or gastrin plus cholecystokinin (CCK) affects the antral G-cell. Immunohistochemistry, radioimmunoassay and quantitative real-time polymerase chain

Activation of bone morphogenetic protein/Smad signaling in bronchial epithelial cells during airway inflammation

Bone morphogenetic proteins (BMPs) are pleiotropic secreted proteins, structurally related to transforming growth factor (TGF)-beta and activins. BMPs play pivotal roles in the regulation of embryonic lung development and branching of airways and have recently been considered to influence inflammatory processes in adults due to their chemotactic activity on fibroblasts, myocytes, and inflammatory

Early rheumatoid arthritis--some social, economical, and psychological aspects

Physical, psychological, and social features were assessed with standardized methods in 84 early RA patients followed prospectively for 2 years. During this time disease activity decreased, and disability evaluated by HAQ remained small. Psychological distress measured by SCL-90 (Symptom Check List) was in general not very pronounced and fairly stable over time. A high pain level at baseline provi

Anti-arthritic effect of methotrexate: is it really mediated by adenosine?

The mechanism of action for the anti-arthritic effect of methotrexate (MTX) was investigated in rats with antigen-induced arthritis (AIA). Arthritis intensity was quantified as area under the curve (AUC) for the joint swelling. The response to MTX was in several respects similar to what is seen in the clinic. The drug reduced the AUC in a dose-dependent manner after oral weekly (2-4 mg/kg/week) or

Norms and descriptions

The problem addressed in this text is the problem of identifying conditions according to which it is possible to distinguish between a descriptive theory and a normative theory. What makes a descriptive theory descriptive and a normative theory normative? Focus is on subjective expected utility theories where it seems open to debate whether the appropriate use is normative or descriptive. My discu

AMINO-ACID-SEQUENCE SIMILARITIES OF THE MITOCHONDRIAL SHORT CHAIN DELTA-3,DELTA-2-ENOYL-COA ISOMERASE AND PEROXISOMAL MULTIFUNCTIONAL DELTA-3,DELTA-2-ENOYL-COA ISOMERASE, 2-ENOYL-COA HYDRATASE, 3-HYDROXYACYL-COA DEHYDROGENASE ENZYME IN RAT-LIVER - THE PROPOSED OCCURRENCE OF ISOMERIZATION AND HYDRATION IN THE SAME CATALYTIC DOMAIN OF THE MULTIFUNCTIONAL ENZYME

We report the isolation and characterization of a cDNA encoding the mitochondrial short chain DELTA-3,DELTA-2-enoyl-CoA isomerase from rat liver. Tryptic fragments of the purified protein were generated, purified, and sequenced. A rat liver cDNA library, constructed in the plasmid vector pUEX1 was screened with oligonucleotides synthesized on the basis of peptide sequences. The obtained clone cont

Three-year follow-up of feedback microwave thermotherapy versus TURP for clinical BPH: A prospective randomized multicenter study

Objectives. To compare, in a prospective randomized multicenter study, the efficacy and safety of transurethral microwave thermotherapy with Prostalund Feedback Treatment (PLFT), using the CoreTherm device, with transurethral resection of the prostate (TURP) 36 months after treatment. Methods. The study was conducted at 10 centers in the United States and Scandinavia. A total of 154 patients with

Efficient solution of the self-consistent field theory for block copolymer fluids displaying Schulz-Flory polydispersity

We develop a new formulation of polymer self-consistent field theory for polydisperse copolymer fluids satisfying the Schulz-Flory distribution. The result we obtain is remarkably simple and quickly solved numerically. The computational effort scales inversely with the width of the Schulz-Flory distribution. This suggests a significant saving in computational effort when compared with existing app