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Community Perceptions of and Vulnerability to Earthquake Disaster : Insights from the City of Dhaka, Bangladesh

This study is an attempt to empirically determine and analyse the factors that significantly influence the perceptions of and vulnerability to an earthquake disaster that struck a community located in the Hazaribagh area of Dhaka South City, Bangladesh. The empirical results reveal a significant relationship between a number of sociodemographic factors and the community's perceptions of and level

Roles of PAD4 and NETosis in Experimental Atherosclerosis and Arterial Injury : Implications for Superficial Erosion

RATIONALE: Neutrophils likely contribute to the thrombotic complications of human atheromata. In particular, neutrophil extracellular traps (NETs) could exacerbate local inflammation and amplify and propagate arterial intimal injury and thrombosis. PAD4 (peptidyl arginine deiminase 4) participates in NET formation, but an understanding of this enzyme's role in atherothrombosis remains scant.OBJECT

Innate lymphoid cells in atherosclerosis

The family of innate lymphoid cells (ILCs) consisting of NK cells, lymphoid tissue inducer cells and the 'helper'-like ILC subsets ILC1, ILC2 and ILC3 have been shown to have important roles in protection against microbes, regulation of inflammatory diseases and involved in allergic reactions. ILC1s produce IFN-γ upon stimulation with IL-12 and IL-18, ILC2s produce IL-5 and IL-13 responding to IL-

Impacts of urban living labs on sustainability transitions : mechanisms and strategies for systemic change through experimentation

Urban Living Labs (ULL) are considered spaces to facilitate experimentation about sustainability solutions. ULL represent sites that allow different urban actors to design, test and learn from socio-technical innovations. However, despite their recent proliferation in the European policy sphere, the underlying processes through which ULL might be able to generate and diffuse new socio-technical co

"En temmelig lang fodtur" : HGIS, Text mining, and folklore collection in 19th century denmark

In Scandinavia, the folklore collection of the nineteenth and early twentieth centuries coincided with rapid changes in political, economic, and social organization, and resulted in national collections of extraordinary scope. Although some later folklorists have expressed skepticism about the usefulness of these collections as resources for the study of folklore, ethnography and intellectual hist

The public prosecution service and the structuring of sentencing - the nordic case of Denmark

This chapter contributes an original description of a very different structuring arrangement of sentencing institutionalized through the Danish prosecution service since the 1990s. The prosecution service has attained a new and bigger role and new techniques add significantly to the structuring of sentencing. The techniques of structuring sentencing are: preparatory works to statutory amendments,

Microbial Mercury Methylation in Aquatic Environments : A Critical Review of Published Field and Laboratory Studies

Methylmercury (MeHg) is an environmental contaminant of concern because it biomagnifies in aquatic food webs and poses a health hazard to aquatic biota, piscivorous wildlife and humans. The dominant source of MeHg to freshwater systems is the methylation of inorganic Hg (IHg) by anaerobic microorganisms; and it is widely agreed that in situ rates of Hg methylation depend on two general factors: th

Family counts : deciding when to murder among the Icelandic Vikings

In small scale societies, lethal attacks on another individual usually invite revenge by the victim's family. We might expect those who perpetrate such attacks to do so only when their own support network (mainly family) is larger than that of the potential victim so as to minimise the risk of retaliation. Using data from Icelandic family sagas, we show that this prediction holds whether we consid

Cells in Culture, Cells in Suspense : Practices of Cultural Production in Foetal Cell Research

Parkinson’s disease is a neurodegenerative affliction to which researchers have long striven to find a cure. The human embryo is a source of vital cells used in regenerative medicine, as well as a powerful symbol of life. Using foetal cells from aborted embryos for transplantation to the brains of Parkinson patients is an avenue that has been explored by neuroscientists on and off for the last thi

NMR studies of the E140Q mutant of the carboxy-terminal domain of calmodulin reveal global conformational exchange in the Ca2+-saturated state

In the present investigation, the Ca2+ activation of the C-terminal domain of bovine calmodulin and the effects of replacing the bidentate Ca2+-coordinating glutamic acid residue in the 12th and last position of loop IV with a glutamine are studied by NMR spectroscopy. The mutation E140Q results in sequential Ca2+ binding in this domain and has far-reaching effects on the structure of (Ca2+)2 TR2C

Nuclear spin quenching a new probe of exchange kinetics and droplet size in disperse systems

A new experimental technique, nuclear spin quenching (NSQ), is introduced, which can be used to measure droplet size and inter-droplet exchange rates of various intrinsic molecular species in disperse systems. The physical basis of the method is the quenching of the fine structure in spin-coupled N.M.R. spectra by intermolecular proton exchange, the rate of which is controlled by droplet exchange.

Sequence dependence and direct measurement of crossover isomer distribution in model Holliday junctions using NMR spectroscopy

A 32-base-pair model of the Holliday junction (HJ) intermediate in genetic recombination has been prepared and analyzed in-depth by 2D and 3D 1H NMR spectroscopy. This HJ (J2P1) corresponds to a cyclic permutation of the base pairs at the junction relative to a previously studied HJ [J2; Chen, S.-M., and Chazin, W. J. (1994) Biochemistry 33, 11453-11459], designed to probe the effect of the sequen

Shape fluctuations and water diffusion in microemulsion droplets : A nuclear spin relaxation study

Water 2H and 17O spin relaxation data for the microemulsion phase in the AOT/D 2O/isooctane system are reported. The difference between the transverse (R 2) and the longitudinal (R 1) relaxation rates has been measured as function of droplet size, droplet volume fraction, temperature, and resonance frequency. The 2H longitudinal relaxation rate dispersion has been measured over an extensive freque

Water Dynamics in Microemulsion Droplets. A Nuclear Spin Relaxation Study

The state of water in aqueous microemulsion droplets in the system AOT/D2O/isooctane has been investigated by 2H and 17O NMR. Longitudinal relaxation rates are reported as a function of droplet size, droplet volume fraction, temperature, and resonance frequency. We conclude that the surface-induced perturbation of water rotation is of short range (limited to the primary hydration of the AOT head g

Primary care doctor fostering and clinical research training in Sweden : Implications for Japan

In 2018, a new training program for primary care physicians was launched in Japan. As physicians responsible for the training of new primary care physicians, we have faced many problems, particularly in rural areas. The influence of this new program on primary care physicians in rural areas of Japan has not been sufficiently investigated. The aim of this research was to improve training for primar

Hydration of ionic surfactant micelles from water oxygen-17 magnetic relaxation

Water oxygen-17 relaxation rates have been measured for aqueous solutions of micelles composed of ionic surfactants of varying alkyl chain length, head group, and counterion. The concentration of surfactant and salt was also varied. From these measurements, supplemented with relaxation data for short-chain molecules and with quadrupolar splittings from anisotropic mesophases, we derive structural