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Obesity and cardiovascular risk : A call for action from the European Society of Hypertension Working Group of Obesity, Diabetes and the High-risk Patient and European Association for the Study of Obesity: Part B: Obesity-induced cardiovascular disease, early prevention strategies and future research directions

Obesity predisposes for atrial fibrillation, heart failure, sudden cardiac death, renal disease and ischemic stroke, which are the main causes of cardiovascular hospitalization and mortality. As obesity and the cardiovascular effects on the vessels and the heart start early in life, even from childhood, it is important for health policies to prevent obesity very early before the disease manifestat

Gräsligt skönt

Jakob's Square, solo show, Belenius/Nordenhake, Stockholm, Mar 21-Apr 19, 2015. (Opening reception Mar 21, 15-19). Gräsligt skönt, essay (in swedish) by Nils-Eric Sahlin

Obesity and cardiovascular risk : A call for action from the European Society of Hypertension Working Group of Obesity, Diabetes and the High-risk Patient and European Association for the Study of Obesity: Part A: Mechanisms of obesity induced hypertension, diabetes and dyslipidemia and practice guidelines for treatment

Obesity is a key factor for cardiovascular diseases and complications. Obesity is associated with hypertension, dyslipidemia and type II diabetes, which are the major predictors of cardiovascular disease in the future. It predisposes for atrial fibrillation, heart failure, sudden cardiac death, renal disease and ischemic stroke that are the main causes of cardiovascular hospitalization and mortali

Acellular human lung scaffolds to model lung disease and tissue regeneration

Recent advances in whole lung bioengineering have opened new doors for studying lung repair and regeneration ex vivo using acellular human derived lung tissue scaffolds. Methods to decellularise whole human lungs, lobes or resected segments from normal and diseased human lungs have been developed using both perfusion and immersion based techniques. Immersion based techniques allow laboratories wit

Fall-risk-increasing drugs and falls requiring health care among older people with intellectual disability in comparison with the general population : A register study

BACKGROUND: Falls are the most common cause of injury for older people in the general population as well as among those with intellectual disability. There are many risk factors for falls, including a range of drugs which are considered to be fall-risk-increasing (FRIDs). The aim of the present study was to describe prescription patterns of FRIDs in itself as well as in relation to falls requiring

Envelope Functions : Unifications and Further Properties

Forward–backward and Douglas–Rachford splitting are methods for structured nonsmooth optimization. With the aim to use smooth optimization techniques for nonsmooth problems, the forward–backward and Douglas–Rachford envelopes where recently proposed. Under specific problem assumptions, these envelope functions have favorable smoothness and convexity properties and their stationary points coincide

A new approach for investigation of person–environment interaction effects in research involving health outcomes

Recurrent use of the Housing Enabler instrument has highlighted methodological challenges of broader scientific interest, namely interactions between personal functional capacity (P) and exposures to features (here potential barriers) in the built housing environment (E). This study aimed to propose and illustrate an analytic approach, separating P × E interaction effects (here accessibility probl

Progression of frailty and prevalence of osteoporosis in a community cohort of older women—a 10-year longitudinal study

Summary: In community dwelling, 75-year-old women followed 10 years, a frailty index was created at each of three visits. Frailty score increased by ~ 6–7% annually. A higher frailty score was equivalent to being 5–10 years chronologically older. Frailty was associated with low bone density and higher risk of dying. Introduction: To understand the distribution of frailty among a population-based s

Individual-based simulation of the spatial and temporal dynamics of macroinvertebrate functional groups provides insights into benthic community assembly mechanisms

The complexity and scales of the processes that shape communities of marine benthic macroinvertebrates has limited our understanding of their assembly mechanisms and the potential to make projections of their spatial and temporal dynamics. Individual-based models can shed light on community assembly mechanisms, by allowing observed spatiotemporal patterns to emerge from first principles about the

Multi-ethnic genome-wide association study for atrial fibrillation

Atrial fibrillation (AF) affects more than 33 million individuals worldwide1 and has a complex heritability2. We conducted the largest meta-analysis of genome-wide association studies (GWAS) for AF to date, consisting of more than half a million individuals, including 65,446 with AF. In total, we identified 97 loci significantly associated with AF, including 67 that were novel in a combined-ancest

Automatic hand phantom map generation and detection using decomposition support vector machines

Background: There is a need for providing sensory feedback for myoelectric prosthesis users. Providing tactile feedback can improve object manipulation abilities, enhance the perceptual embodiment of myoelectric prostheses and help reduce phantom limb pain. Many amputees have referred sensation from their missing hand on their residual limbs (phantom maps). This skin area can serve as a target for

Scheimpflug Lidar for combustion diagnostics

A portable Lidar system developed for large-scale (~1-20 m) combustion diagnostics is described and demonstrated. The system is able to perform remote backscattering measurements with range and temporal resolution. The range resolution is obtained by sharply imaging a part of the laser beam onto a CMOS-array or ICCD detector. The large focal depth required to do this is attained by placing the las

The Challenges of Re-Packaging a Heritage

In the last decade, many museums that were established in the 20th century by immigrants from the Nordic countries have become increasingly concerned with broadening their audiences and more actively engaging their visitors. Efforts to do this have varied from offering cocktail hours, culinary conferences, and sauna sessions, to striving to appeal to people who may not identify as Nordic or do not

Frank Ramsey (1903-1930)

Frank Plumpton Ramsey (1903-1930), British mathematician and philosopher, best known for his work on the foundations of mathematics. But Ramsey also made remarkable contributions to epistemology, semantics, logic, philosophy of science, mathematics, statistics, probability and decision theory, economics and metaphysics.