Chronic lymphocytic leukemia (CLL) is the most common leukemia among adults worldwide. Although genome-wide association studies (GWAS) have uncovered the germline genetic component underlying CLL susceptibility, the potential use of GWAS-identified risk variants to predict disease progression and patient survival remains unexplored. Here, we evaluated whether 41 GWAS-identified risk variants for C

BackgroundHepatitis B virus (HBV) and syphilis have been the most common co-infections that hinder treatment outcomes and increase early mortality among people living with human immunodeficiency virus (PLHIV). In this study, we aimed to determine the burden of HBV and syphilis co-infections and its impact on treatment outcomes among PLHIV in Ethiopia.MethodsWe used data from the Ethiopian Populati

Background: Intra- and interfractional variations in anatomy can cause unplanned substantial alterations of the dose distribution of the target in proton therapy. Motion management methods might be used in order to minimize anatomical variations. In the proton therapy of lung cancer, a potential motion management technique is the use of the voluntary breath-hold approach. The aim of this study was

Background Treatment-related toxicity and quality of life (QoL) considerations are important when counseling patients with localized prostate cancer (PCa). Objective To determine the incidence and longitudinal pattern of late genitourinary (GU) toxicity and QoL after high-dose, intensity-modulated radiotherapy (IMRT). Design, setting, and participants A total of 268 patients with localized PCa wer

This chapter provides an introduction to task engagement as a framework for better understanding how individuals participate in and learn from second language activities in their leisure time. Although the concept is relatively new to second language acquisition research, engagement has been extensively studied in educational science, as a way of operationalising different aspects of students’ par

A growing community is constructing a next-generation file format (NGFF) for bioimaging to overcome problems of scalability and heterogeneity. Organized by the Open Microscopy Environment (OME), individuals and institutes across diverse modalities facing these problems have designed a format specification process (OME-NGFF) to address these needs. This paper brings together a wide range of those c

When we communicate with others, we use a variety of abilities to facilitate and enable that communication. These abilities range from being responsive to others’ communicative cues to making one’s own communication more functional. Such facilitators of communication has been suggested as atypical in the development of autism. Reduced infant responsiveness towards communicative cues -– such as speWhen we communicate with others, we use a variety of abilities to facilitate and enable that communication. These abilities range from being responsive to others’ communicative cues to making one’s own communication more functional. Such facilitators of communication has been suggested as atypical in the development of autism. Reduced infant responsiveness towards communicative cues ­– such as spe

Background: Since the first version of the dietary inflammatory index (DII®) developed in the past decade, several other versions have been developed. However, to date no study has attempted to compare these versions with respect to their associations with biomarkers of inflammation. Objective: We aimed to investigate the relationship between four dietary inflammatory scores [DII, two energy-adjus

Ventricular-arterial coupling (VAC) has independent diagnostic and prognostic value for cardiovascular (CV) risk stratification, but studies on its association with anthropometric and CV factors are sparse in young individuals without overt CV disease. We aim to provide descriptive data regarding VAC and its associations with CV risk factors in young adults without overt CV disease. For 631 (mean

Vår hemgalax vintergatan är inte lika platt som ofta är trott. Dess form är mycket likt en disk där mitten är tätt fylld med stjärnor och antalet stjärnor avtar desto längre bort från mitten man kommer. Sen 1950-talet har vi också vetat att två motsatta ändar i disken är böjda åt olika håll medans mitten av disken är relativt platt. Senare forskning har även visat på att många andra galaxer är böjContext: The Milky Way disc, like the discs of many other spiral galaxies, has been shown to be warped. The growing astrometric data set for stars produced by the Gaia mission allows for more detailed studies of the stellar disc's warp. Aims: We use a full 6-dimensional phase space sample of stars from Gaia DR3 to study the kinematic signature of the Milky Way warp as a function of position i

Universities are increasingly being seen as a positive vehicle for territorial development and regional transformation, with an important role in enhancing Social, Economic and Sustainable Development of territories. The world’s sustainability challenges are listed in the United Nation’s Agenda 2030, that includes Higher Education Institutions (HEIs) as actors that can work in partnership with oth

Pathological disturbance to one's identity is closely linked with mental illness and in particular personality disorders. Current measures of identity pathology within clinical research are nevertheless inconsistently used and present with substantial limitations such as disproportionate focus on adolescence. The Self-Concept and Identity Measure (SCIM) identifies pathological and non-pathological

The thesis discusses how visual artists negotiate the boundaries between their own creative work and AI-aided work, how they establish boundaries with other artists who use AI, and How the relationship between visual artists and clients is mediated in the market with the rising popularity of AI tools. The study found that most artists negotiate meanings to take a stance and, more often than not, a

The objective of this thesis is to develop a methodology for evaluating the performance of material models during biaxial loads. This is done by executing identical punch tests, one in a simulation and one in a physical experiment, and then comparing the results from the two. The material model that is to be evaluated is used in the simulation and a specimen of the corresponding material in the ph