OBJECTIVE: Traditionally, the diagnosis of pleural mesothelioma is based on histological material. Minimally invasive effusion cytology specimens are an alternative that, like biopsies, require ancillary analyses. Validation of immunohistochemical (IHC) analyses on cytology, including the surrogate markers for molecular alterations BAP1 and MTAP, is of interest.METHODS: IHC for eight different mar

Background: Patients with acute respiratory failure caused by cardiogenic pulmonary edema (CPE) may require mechanical ventilation that can cause further lung damage. Our aim was to determine the impact of ventilatory settings on CPE mortality. Methods: Patients from the LUNG SAFE cohort, a multicenter prospective cohort study of patients undergoing mechanical ventilation, were studied. Relationsh

Background and purpose: Motion compensation with MLC tracking was tested for inversely optimized arc radiotherapy with special attention to the impact of the size of the target displacements and the angle of the leaf trajectory. Materials and methods: An MLC-tracking algorithm was used to adjust the MLC positions according to the target movements using information from an optical real-time positio

PURPOSE: Absent lymph flow and chronic inflammationleads to excess subcutaneous adipose tissue deposition.Chronic non-pitting lymphedema does not respond to conservativetreatment or microsurgical procedures becausethey do not target the adipose tissue. Removing the adiposetissue using suction assisted lipectomy (SAL) seems thus tobe a logic treatment strategy.METHODS: Arms: 190 women, mean±SEM age

While institutional critique has long been an important part of artistic practice and theoretical debate in the visual arts, it has long escaped attention in the field of music. This open access volume assembles for the first time an array of theoretical approaches and practical examples dealing with New Music’s institutions, their critique, and their transformations. For scholars, leaders, and pr

Hodgkin lymphoma (HL) survivors have an increased morbidity and mortality from secondary cancers and cardiovascular disease (CD). We evaluate doses with involved node radiotherapy (INRT) delivered as 3D conformal radiotherapy (3D CRT), volumetric modulated arc therapy (VMAT), or proton therapy (PT), compared with the extensive Mantle Field (MF). Patients and methods: For 27 patients with early-sta

The introduction of integrated MRI-radiation therapy systems will offer live intra-fraction imaging. We propose a feasible low-latency multi-plane MRI-linac guidance strategy. In this work we demonstrate how interleaved acquired, orthogonal cine-MRI planes can be used for low-latency tracking of the 3D trajectory of a soft-tissue target structure. The proposed strategy relies on acquiring a pre-tr

Objective: To investigate CITED1 as a potential biomarker of anti-endocrine response and breast cancer recurrence, given its previously determined role in mediating estrogen-dependant transcription. The study is a continuation of earlier work establishing the role of CITED1 in mammary gland development.Results: CITED1 mRNA is associated with estrogen-receptor positivity and selectively expressed i

This study investigates the association between individuals’ concern about contracting COVID-19 and their compliance with recommended preventive and mitigation measures, namely wearing face masks, maintaining social distancing and handwashing, in the context of the Middle East and North Africa (MENA) region. The empirical analysis is based on a panel dataset from the Combined COVID-19 MENA Monitor

In the Asia-Pacific region (APR), extreme precipitation is one of the most critical climate stressors, affecting 60% of the population and adding pressure to governance, economic, environmental, and public health challenges. In this study, we analyzed extreme precipitation spatiotemporal trends in APR using 11 different indices and revealed the dominant factors governing precipitation amount by at

Since access to justice scholarship has gradually become a more multifaceted, international and empirical endeavour, this special issue illustrates a broader scope of contemporary access to justice research from a multi-disciplinary and socio-legal perspective. The issue gathers contributions from European and US scholars, representing different disciplinary backgrounds, such as law, sociology of

Background: Who can or cannot claim to represent other members within the disability rights movement has been discussed for decades, mainly concerning being disabled as an eligibility prerequisite. Aim(s): The aim is to analyse arguments concerning representational claims within a Swedish disability rights organisation (DHR, Disability Human Rights). Method: Every member of DHR was given the oppor

This paper examines constructions of nature as communicated in three films by outdoor company Patagonia. By employing discourse analysis and the theory of spectacle, the films are seen to construct nature as wilderness and thus apart from humans. Speaking as an authority on the matter, Patagonia suggests wilderness ideals as a method of conservation. Together with representations of nature as spec

Dietary interventions modify gut microbiota and clinical outcomes. Weight reduction and improved glucose and lipid homeostasis were observed after adopting an Okinawan-based Nordic diet (O-BN) in individuals with type 2 diabetes. The aim of the present study was to explore changes in metabolomics and gut microbiota during O-BN and correlate changes with clinical outcomes. A total of 30 patients (1

BACKGROUND: 4-hydroxychlorothalonil (HCT, R182281), a transformation product of the fungicide chlorothalonil, was recently identified in human serum and breast milk. There are indications that HCT may be more toxic and environmentally persistent than chlorothalonil.OBJECTIVE: Our aim was to investigate serum concentrations of HCT in pregnant women in Sweden and Costa Rica.METHODS: We developed a q

Recension av Kent Zetterberg, Sverige och Hitler 1939–1945. Ett bidrag till historien om Sverige och Tyskland under andra världskriget.

This corpus-based study examines how writers of tweets about organic food use hashtags to direct readers towards the preferred tweet interpretation while expressing their stance to organic food. Our aim is to identify the functions stance-conveying hashtags serve in these tweets. To this end, we draw on Du Bois’ (2007) approach to stance and Francis’ (1994) analysis of metalinguistic labels. We an

Koncessionsmineral är ämnen som är viktiga för samhället, de behövs för att bygga bilar, telefoner, infrastruktur och mycket mer. Ämnena är även viktiga för att verkställa en grön energiomställning och för uppfyllelse av de nationella miljömålen. För att utvinna dessa ämnen behövs någon form av gruvbrytning, vilket kan ske i underjordsgruvor eller dagbrott. Gruvbrytning är en verksamhet som tar stMetals and minerals are prerequisites for a modern and climate-neutral society. Domestic mining facilities are also an essential part of the Swedish national economy. Sweden has a unique bedrock and is one of Europe's largest producers. However, the willingness to invest in the Swedish mining industry has dropped over the last decade. The main reason for this is the complication and uncertaint