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Parvalbumin- (PV-) containing basket cells constitute perisomatic GABAergic inhibitory interneurons innervating principal cells at perisomatic area, a strategic location that allows them to efficiently control the output and synchronize oscillatory activity at gamma frequency (30–90 Hz) oscillations. This oscillatory activity can convert into higher frequency epileptiform activity, and therefore c
Nurses' patient education is important for building patients' knowledge, understanding, and preparedness for self-management. The aim of this study was to explore the conditions for nurses' patient education work by focusing on managers' discourses about patient education provided by nurses. In 2012, data were derived from three focus group interviews with primary care managers. Critical discourse
Why do people engage in collective actions, such as demonstrations? We suggest that intentions to engage in protest activities come from the perception that the action is an efficient way to affect policy but is also dependent upon the level of others’ engagement. Specifically, lower support should spur intentions to engage if the individual believes that the collective act is an efficient means t
As the production and usage of nanomaterials are increasing so are the concerns related to the release of the material into nature. Tungsten carbide (WC) is widely used for its hard metal properties, although its use, in for instance tyre studs, may result in nano-sized particles ending up in nature. Here, we evaluate the potential long-term exposure effects of WC nanoparticles on a pelagic (Daphn
The research examining the association between quality of diet and abdominal aortic aneurysm (AAA) is scarce. The aim of the present study was to explore the association between diet quality and development of AAA for middle-aged individuals in the Malmö Diet and Cancer Study (MDCS), a prospective cohort study with baseline data collection carried out between 1991 and 1996. At baseline, the study
Cutibacterium (Propionibacterium) acnes, considered a part of the skin microbiota, is one of the most commonly isolated anaerobic bacteria from medical implants in contact with plasma. However, the precise interaction of C. acnes with blood cells and plasma proteins has not been fully elucidated. Herein, we have investigated the molecular interaction of C. acnes with platelets and plasma proteins.
Purpose: The application of proteomics in chronic kidney disease (CKD) can potentially uncover biomarkers and pathways that are predictive of disease. Experimental design: Within this context, this study examines the relationship between the human plasma proteome and glomerular filtration rate (GFR) as measured by iohexol clearance in a cohort from Sweden (n = 389; GFR range: 8-100 mL min-1/1.73 m
We investigated galectin-3 binding to 3-benzamido-2-O-sulfo-galactoside and -thiodigalactoside ligands using a combination of site-specific mutagenesis, X-ray crystallography, computational approaches, and binding thermodynamics measurements. The results reveal a conformational variability in a surface-exposed arginine (R144) side chain in response to different aromatic C3-substituents of bound ga
We studied the systematics of the subfamily Limenitidinae (Lepidoptera: Nymphalidae) using molecular methods to reconstruct a robust phylogenetic hypothesis. The molecular data matrix comprised 205 Limenitidinae species, four outgroups, and 11,327 aligned nucleotide sites using up to 18 genes per species of which seven genes (CycY, Exp1, Nex9, PolII, ProSup, PSb and UDPG6DH) have not previously be
The cleavage fracture probability of ferritic and ferritic/martensitic steels is generally computed using Beremin's model. In this work, a novel approach is developed for Beremin's model to be applicable to crack tip conditions under nonself similar stress field. The modification of Beremin's model corrects the inaccurate integration of local cleavage fracture probabilities of reference volume ele
Many cutting processes, such as chopping, slicing, and carving, consist in 2 different stages: an initial stage of indentation, in which the cutting tool is pushed into the material under the action of an external force, and a second stage, where the target material undergoes a progressive separation. This second stage is characterised by the formation of a fracture surface followed by the cut pro
Entrepreneurship as a scientific field has grown significantly, irrespective of the measures used. In this article we raise the question: How can we understand the evolution and success of entrepreneurship as a scholarly field? In particular, we focus on the social structure of entrepreneurship scholars to explain (1) how they are becoming integrated into larger scholarly communities and (2) how t
Large and complete glaciotectonic sequences formed by marine-terminating glaciers are rarely observed on land, hampering our understanding of the behaviour of such glaciers and the processes operating at their margins. During the Late Weichselian in western Iceland, an actively retreating marine-terminating glacier resulted in the large-scale deformation of a sequence of glaciomarine sediments. Du
