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Distinct roles for laminin globular domains in laminin alpha1 chain mediated rescue of murine laminin alpha2 chain deficiency.

BACKGROUND: Laminin alpha2 chain mutations cause congenital muscular dystrophy with dysmyelination neuropathy (MDC1A). Previously, we demonstrated that laminin alpha1 chain ameliorates the disease in mice. Dystroglycan and integrins are major laminin receptors. Unlike laminin alpha2 chain, alpha1 chain binds the receptors by separate domains; laminin globular (LG) domains 4 and LG1-3, respectively

En princip om internationell öppenhet – 1 kap. 10 § regeringsformen och socialförsäkringsrätten

Artikeln undersöker vad bestämmelsen om Sveriges EU-medlemskap och om internationellt samarbete i 1 kap. 10 § regeringsformen betyder rättsligt för den offentliga förvaltningen, särskilt avseende socialförsäkringsrätten och Försäkringskassan. En bakgrund till bestämmelsen är internationaliseringen av den offentliga rätten. Utvecklingen har inneburit att en stor del av de normer som svenska myndigh

’Treating Threats - the Ethical Dilemmas of Treating Threatening Patients

This paper considers the impact of threats on professional service workers, especially as these emerge in healthcare services. Based on interviews with healthcare professionals and prison guards, this paper discusses the ethical dilemmas inherent in viewing the doctor-patient relationship from a solely rule-based ethical approach when threatening behaviour is involved. It is argued that under thre

CAN AN ENERGY-COMPENSATED SOLID-STATE X-RAY DETECTOR BE USED FOR RADIATION PROTECTION APPLICATIONS AT HIGHER PHOTON ENERGIES?

The objective of this study was to investigate the characteristics of a solid-state detector commonly available at hospitals for parallel use as a real-time personal radiation monitor following radiation emergency situations. A solid-state detector probe with an inherent filtration (R100, RTI Electronics AB, Mölndal, Sweden) was chosen for evaluation. The energy dependence and the linearity in sig

Mediehistoria i Lund

This text describes the ongoing establishment of media history at Lund University and reflects on its two-front strivings. The birth of media history as a proper, albeit small, discipline within the ordinary structure of the faculty, from graduate level to PhD studies, was very much a matter of chance, and easy enough to achieve. Whether this institutionalisation actually will be productive for th