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Characterization of the potassium channels involved in EDHF-mediated relaxation in cerebral arteries

1. In the presence of N(G)-nitro-L-arginine (L-NOARG, 0.3 mM) and indomethacin (10 μM), the relaxations induced by acetylcholine and the calcium (Ca) ionophore A23187 are considered to be mediated by endothelium-derived hyperpolarizing factor (EDHF) in the guinea-pig basilar artery. 2. Inhibitors of adenosine 5'-triphosphate (ATP)-sensitive potassium (K)-channels (K(ATP); glibenclamide, 10 μM), vo

Light–dependent effects of zinc protoporphyrin IX on endothelium–dependent relaxation resistant to NoM–nitro–L–arginine

Acetylcholine (ACh) induces an Nω–nitro–L–arginine (L–NOARG)–resistant relaxation and hyperpolarization in the rat isolated hepatic artery. The possibility that carbon monoxide (CO) produced by haem oxygenase (HO) is an endogenous mediator of this response was investigated. Exogenously applied CO evoked a concentration–dependent relaxation, and the CO ‘scavenger’ oxyhaemoglobin (10μM) reduced the

Helping students to learn without teachers present

Surveys of students’ and teachers’ experiences at the Department of Geology, Lund University, have shown a need and wish among students to get, for example, more practice in using and understanding geological terminology and to understand the context of different features. Among teachers a common problem is (too) limited time per student to always give meaningful feedback and support. Learning mat

Fate of intravenously administerd particulate and lipoprotein choletserol in the rat

Unesterified radioactive cholesterol, both bound to serum lipoproteins and dispersed in ethanol-saline, was injected into bile fistula and intact rats. Due to phagocytosis, mainly by the liver macrophages, intravenously injected cholesterol in ethanol-saline disappears from the bloodstream significantly faster than lipoprotein-bound cholesterol. Soon after the initial phagocytosis, the particulate

The perceived threat of the risk for graft rejection and health related quality of life among organ transplant recipient's.

Aims. This study was primarily aimed for developing and testing a valid and reliable instrument that measures perceived threat of the risk for graft rejection after organ transplantation. A second aim was to report descriptive data regarding graft rejection and Health‐Related Quality of Life.Background. The most serious risk connected with transplantations besides infection is graft rejection.Desi

In-situ SEM study of fracture of an ultrathin Al-foil-modelling of the fracture processes

Fracture behavior of an ultra thin aluminium foil was studied. For very short crack lengths, fracture has been followed in the scanning electron microscope (SEM) with a tensile stage. A single edge notched tension specimen was used. Crack length and applied load during the crack growth were measured. These results have been used to calculate fracture strength using linear elastic fracture mechanicFracture behavior of an ultra thin Aluminium foil was studied. For very short crack lengths, fracture has been followed in the scanner electronic microscope (SEM) with a tensile stage. A single edge notched tension specimen was used. Crack length and applied load during the crack growth were measured. These results have been used to calculate fracture strength using linear elastic fracture mechani

Strain-driven corrosion crack growth - A pilot study of intergranular stress corrosion cracking

This work proposes a model for corrosion driven crack growth. The model poses a moving boundary problem, where a chemical attack removes material from the body. The rate of the chemical attack is a function of the strain along the body surface. No crack growth criterion is needed for the analysis. A finite strain formulation is used and the material model is assumed hyperelastic. The problem is st

Actio som förkroppsligad attityd : En burkesk och multimodal metod för analys av ickeverbal kommunikation

Denna artikel presenterar en studie av attityder som visas i en medlings­situation i en svensk reality-teveserie om grannkonflikter. Syftet är att utveckla en teoretisk och metodologisk ram för retorisk analys av icke­verbala yttranden. I artikeln skisseras en teori baserad på retorikens actio och Kenneth Burkes syn på förkroppsligad attityd. Actio utforskas genom en multimodal analys, det vill sä