Sökresultat

Filtyp

Din sökning på "*" gav 528529 sökträffar

Public space as commodity : Social production of the Hong Kong waterfront

Although there has been a long tradition of public space-related land speculation and development, the recent success of the High Line in New York has highlighted the transformative effect carefully designed and curated public spaces can have on the local economy. By prioritising exchange value over use value, governments and developers are exploiting the production of public spaces as a means for

Circular Economy Policy at a Crossroads: Encouraging Durable Products or Enabling Faster Cycling of Short-lived Products?

Non-ownership models, where firms rather than consumers remain product owners, are advocated as a way for firms to prolong product lifetimes and contribute to a more Circular Economy. However, it has been suggested that such models could actually encourage ‘faster cycling’, meaning earlier product replacement and shorter product lifetimes. Within recent policy discussions, product durability to pr

The European Public Prosecutor: Quintessential Supranational Criminal Law?

This article critically examines the claim that EPPO is a proper federal supranational prosecutor. The article observes that the EPPO among policymakers and commentators appears to be a hallmark of the transformation of EU criminal law from an intergovernmental paradigm to a strong federal and supranational polity. The EPPO primarily stands out among other EU agencies by having been conferred with

Big Science, Ethics, and the Scalar Effects of Urban Planning

The urban expansion currently under development around the two materials science facilities MAX IV and European Spallation Source in Lund, Sweden, surrounds two meticulously designed research facilities steered by global demands. The new urban area, together with the research facilities dedicated to science and the development of knowledge, expands the city of Lund onto high-quality agricultural l

Associations of Plasma Phospho-Tau217 Levels with Tau Positron Emission Tomography in Early Alzheimer Disease

Importance: There is an urgent need for inexpensive and minimally invasive blood biomarkers for Alzheimer disease (AD) that could be used to detect early disease changes. Objective: To assess how early in the course of AD plasma levels of tau phosphorylated at threonine 217 (P-tau217) start to change compared with levels of established cerebrospinal fluid (CSF) and positron emission tomography (PE

Investigating the clinico-anatomical dissociation in the behavioral variant of Alzheimer disease

Background: We previously found temporoparietal-predominant atrophy patterns in the behavioral variant of Alzheimer’s disease (bvAD), with relative sparing of frontal regions. Here, we aimed to understand the clinico-anatomical dissociation in bvAD based on alternative neuroimaging markers. Methods: We retrospectively included 150 participants, including 29 bvAD, 28 “typical” amnestic-predominant

Internationella fredsbyrån och Nobels fredspris : Debatter i fredsfrågan på kongresser och i Nobeltal före 1914

In the 19th century, an extensive liberal and Christian international peace movement developed. In 1891, an umbrella organization, the International Peace Bureau (IPB), based in Bern, was formed to coordinate the international peace work that had previously been divided into a number of different national and international federations. This would prove successful. The establishment of a Nobel Priz

Genome-wide association analysis of type 2 diabetes in the EPIC-InterAct study

Type 2 diabetes (T2D) is a global public health challenge. Whilst the advent of genome-wide association studies has identified >400 genetic variants associated with T2D, our understanding of its biological mechanisms and translational insights is still limited. The EPIC-InterAct project, centred in 8 countries in the European Prospective Investigations into Cancer and Nutrition study, is one of th

Association is not prediction : A landscape of confused reporting in diabetes – A systematic review

Aims: Appropriate analysis of big data is fundamental to precision medicine. While statistical analyses often uncover numerous associations, associations themselves do not convey predictive value. Confusion between association and prediction harms clinicians, scientists, and ultimately, the patients. We analyzed published papers in the field of diabetes that refer to “prediction” in their titles.

Dependence of phase transitions on halide ratio in inorganic CsPb(Br: X I1- x )3perovskite thin films obtained from high-throughput experimentation

In this communication, we present the phase diagram of CsPb(BrxI1-x)3 (0 ≤ x ≤ 1, 300-585 K) obtained by high-throughput in situ GIWAXS measurements of a combinatorial thin film library. We find that all compositions convert to the cubic perovskite phase at high temperature and that the presence of bromide in the films stabilizes the metastable perovskite phases upon cool down. In accordance with

Dense sampling of bird diversity increases power of comparative genomics

Whole-genome sequencing projects are increasingly populating the tree of life and characterizing biodiversity1–4. Sparse taxon sampling has previously been proposed to confound phylogenetic inference5, and captures only a fraction of the genomic diversity. Here we report a substantial step towards the dense representation of avian phylogenetic and molecular diversity, by analysing 363 genomes from

Grain and dietary fiber intake and bladder cancer risk : a pooled analysis of prospective cohort studies

BACKGROUND: Higher intakes of whole grains and dietary fiber have been associated with lower risk of insulin resistance, hyperinsulinemia, and inflammation, which are known predisposing factors for cancer. OBJECTIVES: Because the evidence of association with bladder cancer (BC) is limited, we aimed to assess associations with BC risk for intakes of whole grains, refined grains, and dietary fiber.

Transport, destruction, and growth of pebbles in the gas envelope of a protoplanet

We analyze the size evolution of pebbles accreted into the gaseous envelope of a protoplanet growing in a protoplanetary disk, taking into account collisions driven by the relative sedimentation speed as well as the convective gas motion. Using a simple estimate of the convective gas speed based on the pebble accretion luminosity, we find that the speed of the convective gas is higher than the sed

Oumuamuas Passing through Molecular Clouds

The detections of 1I/‘Oumuamua and 2I/Borisov within just two years of each other impressively demonstrate that interstellar objects (ISOs) must be common in the Milky Way. Once released from their parent system, these ISOs travel for billions of years through interstellar space. While often imagined as empty, interstellar space contains gas and dust most prominent in the form of molecular clouds.

Association of amyloid-β CSF/PET discordance and tau load 5 years later

OBJECTIVE: To investigate the association between discordant β-amyloid (Aβ) PET and CSF biomarkers at baseline and the emergence of tau pathology 5 years later. METHODS: We included 730 Alzheimer's Disease Neuroimaging Initiative (ADNI) participants without dementia (282 cognitively normal, 448 mild cognitive impairment) with baseline [18F]florbetapir PET and CSF Aβ42 available. Aβ CSF/PET status

Production of b b ¯ at forward rapidity in p+p collisions at s =510 GeV PRODUCTION of b b ¯ at FORWARD RAPIDITY ... ACHARYA U et al..

The cross section of bottom quark-antiquark (bb¯) production in p+p collisions at s=510 GeV is measured with the PHENIX detector at the Relativistic Heavy Ion Collider. The results are based on the yield of high mass, like-sign muon pairs measured within the PHENIX muon arm acceptance (1.21 GeV/c, and dimuon mass of 5-10 GeV/c2. The extrapolated total cross section at this energy for bb¯ productio

Spontaneous Self-Assembly of Thermoresponsive Vesicles Using a Zwitterionic and an Anionic Surfactant

Spontaneous formation of vesicles from the self-assembly of two specific surfactants, one zwitterionic (oleyl amidopropyl betaine, OAPB) and the other anionic (Aerosol-OT, AOT), is explored in water using small-angle scattering techniques. Two factors were found to be critical in the formation of vesicles: surfactant ratio, as AOT concentrations less than equimolar with OAPB result in cylindrical

Direct Three-Dimensional Imaging of an X-ray Nanofocus Using a Single 60 nm Diameter Nanowire Device

Nanoscale X-ray detectors could allow higher resolution in imaging and diffraction experiments than established systems but are difficult to design due to the long absorption length of X-rays. Here, we demonstrate X-ray detection in a single nanowire in which the nanowire axis is parallel to the optical axis. In this geometry, X-ray absorption can occur along the nanowire length, while the spatial

Description and prediction of reading decoding skills in Swedish children with Developmental Language Disorder

Aim: Research is lacking in terms of reading decoding skills among clinical samples of Swedish-speaking children with Developmental Language Disorder (DLD). Method: The present cross-sectional study included a sample of 61 children (8-12 years) with DLD attending school language units, years 1 to 5. Our purpose was to study reading decoding skills and predictors for decoding, such as a phonologica