Abstract: Proteomics has the potential to deliver disease-associated biomarkers that could provide diagnostic, prognostic and predictive information to enable precision medicine. Affinity proteomics, most commonly based on antibodies and their ability to specifically capture target proteins, has emerged has a valuable tool in biomarker discovery. Our group has developed a recombinant antibody micr

Aims: To quantify the association of self-reported walking pace and handgrip strength with all-cause, cardiovascular, and cancer mortality. Methods and results: A total of 230 670 women and 190 057 men free from prevalent cancer and cardiovascular disease were included from UK Biobank. Usual walking pace was self-defined as slow, steady/average or brisk. Handgrip strength was assessed by dynamomet

and international research projects have attempted to measure andquantify the importance of ecosystem goods and services for people.Nowadays, it is safe to claim that ecosystems, through their naturalprocesses and functions, provide services that are essential for humanwell-being. However, in industrialized societies people often forgethow intricately our daily lives depend on natural ecosystems a

We investigate how the stereotype of the poor (vs. middle class) influences behavioral predictions. In Study 1 participants made predictions regarding another person’s economic behavior in scenarios pertaining to rate of time preferences (loss, gain of smaller and larger amount). We find that participants, across scenarios, expect individuals with low SES to show more short-sightedness, i.e., steeWe investigate how the stereotype of the poor (vs. middle class) influences behavioral predictions. In Study 1, participants made predictions regarding another person’s economic behavior in scenarios pertaining to rate of time preferences (loss, gain of smaller and larger amount). We find that participants, across scenarios, expect individuals with low SES to show more short-sightedness—i.e., stee

Light emission induced by inner-shell excitation of [Formula Presented] molecules has been investigated in the wavelength region [Formula Presented] Synchrotron radiation from the SuperACO storage ring in Orsay (France) has been used for the photoexcitation and a high-resolution secondary monochromator [Formula Presented] for the spectral analysis of the fluorescence light. Vibrationally resolved

Induced pluripotent stem cells (iPSCs) or their progeny, derived from human somatic cells, can give rise to functional improvements after intracerebral transplantation in animal models of stroke. Previous studies have indicated that reactive gliosis, which is associated with stroke, inhibits neurogenesis from both endogenous and grafted neural stem/progenitor cells (NSPCs) of rodent origin. Here w

Semiconductor Bi2O2Se nanolayers of high crystal quality have been realized via epitaxial growth. These two-dimensional (2D) materials possess excellent electron transport properties with potential application in nanoelectronics. It is also strongly expected that the 2D Bi2O2Se nanolayers can be an excellent material platform for developing spintronic and topological quantum devices if the presenc

The poster briefly presents some main traits on how medical practice and understanding changed during the middle ages and renaissance, and how it is mirrored in material culture. A development well on its way during the first half of the middle ages seems to have been interrupted by the Great Death and after that new ideas from abroad were allowed to have a greater influence. A major explanation t

Background Strength training has shown effects in reducing neck pain. As neck pain is highly prevalent in tension-type headache (TTH), it is relevant to examine the effect of strength training of the shoulder muscles on TTH patients. Aim To examine the effect of strength training of the shoulder/neck muscles on TTH frequency and duration. Methods Sixty patients with TTH were randomised into streng

Polycrystalline Cubic Boron Nitride (PCBN) has been considered as the main cutting tool material for hard turning, which has the comparable surface finish quality as grinding, and high efficiency, economical technology in production. It is well known that the abrasiveness of the workpiece have the very important role of the machinability of the materials. Therefore, the tool wear of the PCBN inser

AIM: The aim of this article is to investigate if children (7-17 years) with frequent episodic tension-type headache (FETTH) or chronic TTH (CTTH) have an altered pain perception compared to healthy controls.METHODS: We applied a pressure of five increasing intensities to m. trapezius and m. temporalis with a Somedic Algometer II. Visual analogue scale-score was rated and area under the curve (AUC

This paper presents a robust phase-based positioningframework using a massive multiple-input multiple-output(MIMO) system. The phase-based distance estimates of MPCstogether with other parameters are tracked with an ExtendedKalman Filter (EKF), the state dimension of which varies withthe birth-death processes of paths. The iterative maximumlikelihoodestimation algorithm (RIMAX) and the modeling of

Progress with respect to enrichment and separation of native membrane components in complex lipid environments, such as native cell membranes, has so far been very limited. The reason for the slow progress can be related to the lack of efficient means to generate continuous and laterally fluid supported lipid bilayers (SLBs) made from real cell membranes. We show in this work how the edge of a hyd