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S100B Profiles and Cognitive Function at High Altitude
Bjursten, Henrik, Per Ederoth, Engilbert Sigurdsson, Magnus Gottfredsson, Ingvar Syk, Orri Einarsson, and Tomas Gudbjartsson. S100B profiles and cognitive function at high altitude. High Alt. Med. Biol. 11:31-38, 2010.-Exposure to high altitude can lead to acute mountain sickness (AMS) and high altitude cerebral edema (HACE). In this study we investigated the effect of high altitude on neurocognit
Optical Characterization of Micro-porous Ceramics Using Tunable Diode Laser
The properties of micro-porous ceramics are studied in the present work using a tunable diode-laser-based setup. The relative optical porosity is retrieved by using gas in scattering media absorption spectroscopy (GASMAS) - which yields the path length travelled by photons through the gas-filled pores - and frequency domain photon migration (FDPM) - which evaluates the mean optical path length (MO
Building type production and everyday life: rethinking building types through actor-network theory and object-oriented philosophy
The aim of this paper is to reconceptualise ‘building type’ in order to better account for its general role in society and everyday life. The paper merges the concept of building type with actor-network theory and object-oriented philosophy in order to develop the concept of ‘territorial sorts’ as a way of widening building-type research and making it more useful for investigating how building typ
Radiological and clinical outcomes of using Chartis (TM) to plan endobronchial valve treatment
One-way endobronchial valves (EBVs) have been shown to relieve symptoms of emphysema, particularly in patients without collateral ventilation (CV) between the target and adjacent lobes. In this study, we investigated the ability of the bronchoscopic Chartis (TM) Pulmonary Assessment System to predict treatment response by determining the presence of CV. 80 EBV patients underwent a pre-treatment Ch
Large-Scale Gene-Centric Meta-analysis across 32 Studies Identifies Multiple Lipid Loci
Genome-wide association studies (GWASs) have identified many SNPs underlying variations in plasma-lipid levels. We explore whether additional loci associated with plasma-lipid phenotypes, such as high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), and triglycerides (TGs), can be identified by a dense gene-centric approach. Our meta-ana
Intramyocardial Hemorrhage in Acute Myocardial Infarction: Prognostic Biomarker and Treatment Target?
How to Develop Patient-Centered Research: Some Perspectives Based on Surveys Among People With Rheumatic Diseases in Scandinavia
Patient-centered research addresses the research agenda of patients and captures aspects of health and functioning that they consider important. Yet, those who live with a disease or condition have limited influence when it comes to setting the research agenda, and we know little about how they experience being participants in research studies. Furthermore, knowledge is limited concerning factors
Survivorship after childhood cancer: PanCare: A European Network to promote optimal long-term care.
Survival after childhood cancer has improved substantially over recent decades. Although cancer in childhood is rare increasingly effective treatments have led to a growing number of long-term survivors. It is estimated that there are between 300,000 and 500,000 childhood cancer survivors in Europe. Such good survival prospects raise important questions relating to late effects of treatment for ca
A survey-based choice experiment on coca cultivation
From 1997 to 2005, an astonishing 5200 million USD was invested to reduce cocaine production in Colombia, the world's main cocaine producer. However, little is known about the effectiveness of policies targeting coca cultivation. This paper uses a survey-based experiment to evaluate the effects of the two main policies: eradication and alternative development programs. Our results support Becker's
Med Vila-Matas i Gutenberggalaxen
Review essay of Vila-Matas novel Dublinesk
Outcome measures for primary Sjögren's syndrome: A comprehensive review.
Lymphocytic infiltration of different exocrine and non-exocrine epithelia is the pathological hallmark of primary Sjögren's syndrome, whereas involvement of salivary and lachrymal glands with the clinical counterpart of dry eye and dry mouth are the predominant features of the disease, together with fatigue and musculoskeletal pain. In addition, systemic manifestations, like arthritis, skin vascul
A Missense Mutation in the Aggrecan C-type Lectin Domain Disrupts Extracellular Matrix Interactions and Causes Dominant Familial Osteochondritis Dissecans
Osteochondritis dissecans is a disorder in which fragments of articular cartilage and subchondral bone dislodge from the joint surface. We analyzed a five-generation family in which affected members had autosomal-dominant familial osteochondritis dissecans. A genome-wide linkage analysis identified aggrecan (ACAN) as a prime candidate gene for the disorder. Sequence analysis of ACAN revealed heter
Water, energy and food interactions-Challenges and opportunities
Water and energy are inextricably linked, and as a consequence both have to be addressed together. This is called the water-energy nexus. When access to either is limited, it becomes obvious that it is necessary to consider their interdependence. Population growth, climate change, urbanization, increasing living standards and food consumption will require an integrated approach where food, water a
Horse heart cytochrome c entrapped into the hydrated liquid-crystalline phases of phytantriol: X-ray diffraction and Raman spectroscopic characterization
Small angle X-ray diffraction (SAXD), resonance Raman (RR) spectroscopy with 413 nm excitation, and non-resonance Raman technique with 785 nm excitation were used to probe the influence of entrapped cytochrome c (Cyt c) on the structure of hydrated phytantriol (Phyt) liquid-crystalline phases as well as conformational changes of heme group and secondary structure of the protein. SAXD measurements
Proteolysis Of Human Aggrecan With Mmp-3
Targeting the Mechanisms of Progression in Castration-resistant Prostate Cancer.
End-of-life care in oxygen-dependent COPD and cancer: a national population-based study.
A massive input of coarse-grained siliciclastics in the Pyrenean Basin during the PETM: the missing ingredient in a coeval abrupt change in hydrological regime
The Paleocene-Eocene thermal maximum (PETM) is represented in numerous shallow and deep marine sections of the south-central and western Pyrenees by a 2-4 m thick unit (locally up to 20 m) of clays or marly clays intercalated within a carbonate-dominated succession. This unit records a massive input into the Pyrenean Gulf of fine-grained terrestrial siliciclastics, attributed to an abrupt hydrolog
Hyaluronan in Non-Surgical and Surgical Periodontal Therapy. A Systematic Review.
AIM: To evaluate the effect of hyaluronan (HY) application as monotherapy or as adjunct to non-surgical and/or surgical periodontal therapy. METHODS: Literature search was performed according to PRISMA guidelines with the following main eligibility criteria: (a) English or German language; (b) preclinical in-vivo or human controlled trials; (c) effect size of HY evaluated histologically or clinic