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Biochemical serum markers for brain damage: A short review with emphasis on clinical utility in mild head injury

Purpose. To provide an overview of clinical research on the use of biochemical serum markers for traumatic brain injury (TRI) in the evaluation of patients with mild head injuries (MHI). Methods. The MEDLINE database was searched for publications on biochemical serum markers of TBI until August 2002. Clinical studies addressing their use in MHI were reviewed. Results. Desirable characteristics for

Surface states on GaN(000(1)over-bar)(1x1) - an angle-resolved photoemission study

We present the results of angle-resolved photoemission studies on the (0 0 0 (1) over bar) (N-polar) surface of bulk gallium nitride crystals. The bulk and surface band Structure was investigated along Gamma-A and Gamma-K-M directions on the surface with (1 x 1) symmetry. The sets of spectra were obtained in normal and off-normal emission for the surface prepared by Ar+ ion sputtering and annealin

Fallet Raoul Wallenberg, Vilmos Böhm och Stalin

Wilhelm Agrell har på grundval av sin analys av Venonas material i sin bok Venona dragit slutsatserna att Orestes var Böhm och att de sovjetiska underrättelseorganen hade kunskap om Wallenbergs relation med War Refugee Board. På grundval av SOU:18 2003 vet vi att Wallenberg rapporterade till Böhm om tyska planer på separatfred med västmakterna. Det är ett välbekant faktum, att Josef Stalin dels ka

Direct benefits and the evolution of female-biased cooperative breeding in Seychelles warblers

Inclusive fitness benefits have been suggested to be a major selective force behind the evolution of cooperative breeding. We investigated the fitness benefits selecting for cooperative breeding in the Seychelles warbler, Acroccphalus sechellensis. A microsatellite-based genotyping method was used to determine the relatedness of subordinates to group offspring in an isolated population of Seychell

Trisomies in Hematologic Malignancies

Acquired clonal chromosome aberrations, closely associated with leukemogenesis, are found in many hematologic malignancies. Although the balanced rearrangements, such as translocations and inversions, are the ones most commonly thought of in the context of leukemias, gains of chromosomes ? e.g.., trisomies ? are also frequent. Little is known about the biologic outcome, the pathogenetic significan

Hereditary prostate cancer: clinical aspects

PURPOSE: We review the current epidemiological and genetic knowledge regarding hereditary prostate cancer, and outline its clinical implications. MATERIALS AND METHODS: Published articles on hereditary prostate cancer were identified using the MEDLINE data base. RESULTS: A risk of prostate cancer, particularly early onset disease, is strongly affected by family history (number of relatives with pr

Missense mutations affecting a conserved cysteine pair in the TH domain of Btk

Tec family protein tyrosine kinases have in their N-terminus two domains, The PH domain is followed by Tec homology (TH) domain, which consists of two motifs, The first pattern, Btk motif, is also present in some Pas GAP molecules, C-terminal half of the TH domain, a proline-rich region, has been shown to bind to SH3 domains, Mutations in Bruton's tyrosine kinase (Btk) belonging to the Tec family

Does Ego meet Alter — in the Global Village? A View from Cultural Semiotics

Starting out from the rather different views on Ego and Alter formulated by Peirce and Bakhtin, and, more indirectly, by Foucault, the present contribution attempts to characterise the position of these familiar philosophical personages within the framework of cultural semiotics, as it has been adapted in Lund from the models of the Prague and Tartu schools. The resulting model is tried out in a c

Recognition molecules of the complement system: C1q and mannan-binding lectin in autoimmunity and immune defence

Popular Abstract in Swedish C1q, en delkomponent av C1 molekylen, och mannan-bindande protein (MBL) är igenkänningsmolekyler i komplementsystemet. De har likartad struktur. C1q binder till IgG och IgM och aktiverar den klassiska vägen. MBL binder till kolhydratstrukturer och aktiverar lektinvägen. Autoantikroppar mot C1q förekommer ofta vid svår systemisk lupus erythematosus (SLE) och förekommer oThe C1 subcomponent C1q and the mannan-binding lectin (MBL) are recognition proteins of the complement system, and have similar structure. C1q binds to IgG and IgM and activates the classical pathway. MBL binds to carbohydrate structures and activates the lectin pathway. Autoantibodies to C1q are frequently found in severe systemic lupus erythematosus (SLE) and are present in virtually all patient

The Vulnerable Power of Worship A Study of a Power Approach to Contextualization in Christian Mission

This dissertation deals with the process of contextualizing the Christian discourse with a specific focus on worship and power negotiation. The study is based on literature, interviews and approximately six months of fieldwork in the U.S. in the years 1996,1998, and 2004. I focus on negotiation of power in the light of increasing Christian encounter with different cultural contexts and changing pe

Molecular cytogenetic characterization of t(14;19)(q32;p13), a new recurrent translocation in B cell malignancies

Translocations involving an immunoglobulin (IG) locus are a recurring theme in B cell neoplasia. The rearrangements lead to the joining of an IG gene with a (proto)oncogene, whereby the latter comes under the influence of transcription-stimulating sequences in the constitutively active IG locus resulting in deregulation of the oncogene and neoplastic growth. We present here three cases of B cell n

Efficient production of native, biologically active human cystatin C by Escherichia coli

A cDNA encoding the mature human cysteine proteinase inhibitor cystatin C was fused to the coding sequence for the Escherichia coli outer membrane protein A signal peptide, and the recombinant gene was expressed in E. coli under the control of the λ PR promoter, an optimized Shine-Dalgarno sequence and the λ cI 857 repressor. When induced at 42°C, such cells expressed large amounts of recombinant