Sökresultat

Filtyp

Din sökning på "*" gav 529251 sökträffar

Towards systematic and objective evaluation of police officer performance in stressful situations

To ensure a continuous high standard of police units, it is critical to recruit people who perform well in stressful situations. Today, this selection process includes performing a large series of tests, which still may not objectively reveal a person’s capacity to handle a life-threatening situation when subjected to high levels of stress. To obtain more systematic and objective data, 12 police o

Searches for scalar leptoquarks and differential cross-section measurements in dilepton–dijet events in proton–proton collisions at a centre-of-mass energy of √s = 13 TeV with the ATLAS experiment

Searches for scalar leptoquarks pair-produced in proton–proton collisions at s=13 TeV at the Large Hadron Collider are performed by the ATLAS experiment. A data set corresponding to an integrated luminosity of 36.1 fb- 1 is used. Final states containing two electrons or two muons and two or more jets are studied, as are states with one electron or muon, missing transverse momentum and two or more

Patient-reported quality of life and hand disability in elderly patients after a traumatic hand injury - A retrospective study

Background: Hand injuries occur at any age and cause disability in hand and arm function as well as impaired quality of life, but no study has focused on hand disability and quality of life in the elderly after a hand injury. Globally, the population over 60 years of age is expected to double by 2050 and more hand injuries are estimated among the elderly population. Our goal is to obtain more info

Climatic Conditions : Conventional and Nanotechnology-Based Methods for the Control of Mosquito Vectors Causing Human Health Issues

Climate variability is highly impacting on mosquito-borne diseases causing malaria and dengue fever across the globe. Seasonal variability change in temperature and rainfall patterns are impacting on human health. Mosquitoes cause diseases like dengue fever, yellow fever, malaria, Chikungunya, West Nile and Japanese encephalitis. According to estimations by health organizations, annually one milli

The influence of the major histocompatibility complex (H-2) on experimental diabetes in mice

Mice with different histocompatibility loci on an identical background genome (congenic resistant lines of mice) were used to study the possible influence of the histocompatibility complex on experimental diabetes. The major histocompatibility complex (H-2) was not found to influence the diabetogenic effect of encephalomyocarditis (EMC) virus. In contrast the glucose intolerance following heterolo

5′-AMP hydrolysis by suspensions and homogenates of pancreatic islet cells from normal and cortisone-treated rats

Suspensions of endocrine pancreas cells were prepared by shaking collagenase-isolated rat islets of Langerhans in calcium-free buffer. When incubated with 1.0 mM substrate at pH 7.4, the cells split, Pi from 5′-AMP at a rate of 87 nmol/h per μg DNA, and from β-glycerophosphate at a rate of 25 nmol/h per μg DNA Km for 5′ AMP was about 54 μM. Adenosine or theophylline inhibited the 5′-AMP hydrolysis

Detection and possible functional influence of antibodies directed againt the pancreatic islet cell surface.

Antibodies directed towards determinants on the surface of rat islet cells can be detected qualitatively by the indirect immunofluorescence or quantitatively by a specific radioassay for IgG. Antibodies are found in insulin-dependent diabetics or in rabbits immunized with islet cells. Such antibodies may affect the B-cell function as indicated by the inhibition of incorporation of radioactive leuc

Islet-Cell-Surface Antibodies in Juvenile Diabetes Mellitus

Using an indirect immunofluorescence test on suspensions of viable, insulin-producing islet cells from rats, we found that 32 per cent (28/88) of insulin-treated patients with juvenile diabetes have isletcell-surface antibodies in their circulation. These antibodies also occurred in four of nine children with glucose intolerance, in one of 24 healthy children and in nondiabetic children with thyro

Possible toxic effects of normal and diabetic patient serum on pancreatic B-cells

Serum from normal blood-donors and juvenile diabetic patients inhibited Rb+ accumulation and stimulated release of 51Cr and insulin in suspensions of dispersed pancreatic islet cells prepared from ob/ob mouse islets, which are rich in B-cells. The effects indicate the presence of a B-cytotoxic factor in human serum. Serum from mouse and fetal calf also inhibited the islet cell accumulation of Rb+.

Scanning electron microscopy of surface changes on dispersed pancreatic β-cells following stimulation of insulin release

The surface structure of isolated viable β-cells was studied by scanning electron microscopy. Suspensions of islet cells were prepared from the β-cell-rich islets of the ob/ob mouse. Cells incubated with and without D-glucose were fixed while in suspensions, filtered onto Nucleopore filters and prepared for scanning electron microscopy by the critical point drying procedure. After incubation in gl

Potassium ion-activated hydrolysis of p-nitrophenyl phosphate in pancreatic islet-cell membranes

Hydrolysis of p nitrophenyl phosphate was measured in a fraction enriched in plasma membranes from pancreatic islets of non inbred ob/ob mice. Hydrolysis was stimulated by K+ (10mM) in the pH range 5-10; a small peak of K+ induced activation was observed between pH 7.5 and 8. Both the K+ induced activation and the hydrolysis in the absence of K+ were Mg2+ dependent; maximum activation was obtained

Alloxan cytotoxicity in vitro : Inhibition of rubidium ion pumping in pancreatic β cells

Exposing micro-dissected pancreatic islets of non-inbred ob/ob mice to 2-5 mM-alloxan for 10 min decreased the ability of the islets to accumulate Rb+. Rb+ accumulation in pieces of exocrine pancreas was unaffected by alloxan. When islets were treated with alloxan in the presence of 2-20 mM-D-glucose, the Rb+-accumulating ability was protected in a dose-dependent manner. The protective action of D

Tracing charge transfer in argon dimers by XUV-pump IR-probe experiments at FLASH

Charge transfer (CT) at avoided crossings of excited ionized states of argon dimers is observed using a two-color pump-probe experiment at the free-electron laser in Hamburg (FLASH). The process is initiated by the absorption of three 27-eV-photons from the pump pulse, which leads to the population of Ar2+*-Ar states. Due to nonadiabatic coupling between these one-site doubly ionized states and tw