PURPOSE: Circular smooth muscle of the urethra generates spontaneous myogenic tone of relevance for the maintenance of continence. We tested if Rho guanosine triphosphatases (GTPases) and Rho-associated kinase (ROK) are involved in the generation of urethral tone. MATERIALS AND METHODS: Small circular strips of female pig urethra were dissected out and mounted for recording isometric force. The ef

BACKGROUND: Recent reports have shown that, although rare, findings of mucosal ulcers and perforations of the nasal septum in some cases may be associated with the use of topical nasal glucocorticosteroids (GCS). It can been speculated that, a reduction in septal mucosal blood flow causing ischemia may eventually induce septal perforations. AIM: To evaluate whether a single dose of a potent nasal

The limitations of water mist in acting as a total flooding agent are discussed in this paper. The paper focuses on water mist consisting of droplets 1-100 µm in diameter. Water mists are very efficient as an extinguishing media if they are present in the flame. There are, however, several problems associated with introducing the water mist into the flame: the spray reaches only a short distance;

Popular Abstract in Swedish Villkoren för utbildning och undervisning förändras i väsentliga avseenden i takt med samhällets tilltagande komplexitet. Det är många gånger svårt för både lärare och elever att veta hur man på bästa sätt ska orientera sitt pedagogiska handlande. Med utgångspunkt från tre pedagogiska kontexter - grundskolan, de särskilda ungdomshemmen och grundskollärarutbildningen - pPedagogical practice is, in several important considerations, contradictory in character. In this dissertation attenention is drawn towards the field of tension that prevails between pedagogical action, which can be descibed in terms of strategic processes and communicative pedagogical action. While the former places the preconditions for effective knowledge development of the individual at the ce

Popular Abstract in Swedish Priset på en produkt sägs vara icke-lineärt om styckpriset på produkten inte är konstant utan beror på den kvantitet (eller kvalitet) som konsumenten köper. Denna typ av prissättning är vanligt förekommande när man exempelvis prissätter vatten eller elektricitet och har många önskvärda egenskaper. Till exempel är det ofta nödvändigt med icke-lineära priser för att uppnåThe price of a good is said to be nonlinear if the unit price not is constant but depends on some aspect of the quantity (or quality) purchased. This form of pricing is commonly used in many industries, e.g. the electricity and water industries, and has many desirable properties. For example, nonlinear pricing is often necessary for (Pareto) efficiency and nonlinear pricing can be used as an instr

The psychometric properties of a Swedish version of Haidt, McCauley and Rozin's (1994) Disgust Scale were studied. Confirmatory factor analysis of the original model with eight factors (food, animals, body products, sex, body envelope violations, death, hygiene, and magic) provided satisfactory fit to the data (N= 280), significantly better than to the alternative one-factor and five-factor models

We have examined a family with a germline BRCA2 mutation in three cases of invasive breast cancer and one case of ductal carcinoma in situ ( DCIS). Loss of heterozygosity (LOH) has been demonstrated at the BRCA2 locus in all cases. This result may suggest that the germline mutation in BRCA2 is the initiating step of DCIS and support the theory that DCIS is a precursor of invasive breast carcinoma

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A 9000-year carbonate-rich sediment sequence from a small hard-water lake in northernmost Sweden was studied by means of multi-component stable carbon isotope analysis. Radiocarbon dating of different sediment fractions provides chronologic control and reveals a rather constant hard-water effect through time, suggesting lake has remained hydrologically open throughout the Holocene. Successive depl

1 In the present study, the inhibitory effects of the selective beta 2-adrenoceptor agonists, salmeterol, formoterol and salbutamol, have been investigated on contractions of ferret trachea induced both by endogenous and exogenous acetylcholine. The aim of the study was to evaluate quantitative and/or qualitative differences in response which may indicate both pre-and post-junctional sites of acti

Histomorphologic differences of the periarticular bone in rheumatoid arthritis (RA) and osteoarthrosis (OA) may be of importance for long-term prosthetic fixation. We have evaluated bone specimens, obtained during total hip replacement from an acetabular and a femoral biopsy site, in 42 RA-hips and 61 OA-hips. In both groups the bone turnover was increased in the acetabulum compared to that in the

Bikunin is a chondroitin sulfate-containing plasma protein synthesized in the liver. In vitro, it has been shown to inhibit proteases and to have additional activities, but its biological function is still unclear. Here we have studied the dynamics of plasma bikunin in rats and mice. A half-life of 7 +/- 2 min was obtained from the time course of the decrease of the plasma level of bikunin followi